| 1 |
35063765 | Differential growth inhibition, cell cycle arrest and apoptosis of MCF-7 and MDA-MB-231 cells to holocarboxylase synthetase suppression. | 2022 Feb 19 |
4 |
| 2 |
32727382 | Clinical, biochemical, and genetic analysis of a Chinese Han pedigree with holocarboxylase synthetase deficiency: a case report. | 2020 Jul 29 |
1 |
| 3 |
32727786 | Overexpression of Holocarboxylase Synthetase Predicts Lymph Node Metastasis and Unfavorable Prognosis in Breast Cancer. | 2020 Aug |
4 |
| 4 |
28564555 | Holocarboxylase Synthetase: A Moonlighting Transcriptional Coregulator of Gene Expression and a Cytosolic Regulator of Biotin Utilization. | 2017 Aug 21 |
8 |
| 5 |
26601567 | Biotin-dependent functions in adiposity: a study of monozygotic twin pairs. | 2016 May |
1 |
| 6 |
24239178 | Holocarboxylase synthetase acts as a biotin-independent transcriptional repressor interacting with HDAC1, HDAC2 and HDAC7. | 2014 Mar |
5 |
| 7 |
24361214 | Holocarboxylase synthetase: a multitalented protein with roles in biotin transfer, gene regulation and chromatin dynamics. | 2014 Mar |
1 |
| 8 |
24684412 | Novel roles of holocarboxylase synthetase in gene regulation and intermediary metabolism. | 2014 Jun |
4 |
| 9 |
24840043 | Holocarboxylase synthetase interacts physically with nuclear receptor co-repressor, histone deacetylase 1 and a novel splicing variant of histone deacetylase 1 to repress repeats. | 2014 Aug 1 |
2 |
| 10 |
25466176 | β-Keto and β-hydroxyphosphonate analogs of biotin-5'-AMP are inhibitors of holocarboxylase synthetase. | 2014 Dec 15 |
2 |
| 11 |
23219734 | Biotinylation of lysine 16 in histone H4 contributes toward nucleosome condensation. | 2013 Jan 15 |
2 |
| 12 |
23337344 | Holocarboxylase synthetase interacts physically with euchromatic histone-lysine N-methyltransferase, linking histone biotinylation with methylation events. | 2013 Aug |
2 |
| 13 |
24007195 | Epigenetic synergies between biotin and folate in the regulation of pro-inflammatory cytokines and repeats. | 2013 Nov |
2 |
| 14 |
24278788 | Holocarboxylase synthetase 1 physically interacts with histone h3 in Arabidopsis. | 2013 |
1 |
| 15 |
21894551 | A novel molecular mechanism to explain biotin-unresponsive holocarboxylase synthetase deficiency. | 2012 Jan |
6 |
| 16 |
22027809 | Effects of single-nucleotide polymorphisms in the human holocarboxylase synthetase gene on enzyme catalysis. | 2012 Apr |
9 |
| 17 |
22123817 | Selectivity in post-translational biotin addition to five human carboxylases. | 2012 Jan 13 |
9 |
| 18 |
22192339 | K16-biotinylated histone H4 is overrepresented in repeat regions and participates in the repression of transcriptionally competent genes in human Jurkat lymphoid cells. | 2012 Dec |
2 |
| 19 |
20688500 | Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18. | 2011 May |
7 |
| 20 |
21195703 | A 96-well plate assay for high-throughput analysis of holocarboxylase synthetase activity. | 2011 Apr 11 |
2 |
| 21 |
21303649 | Identification of holocarboxylase synthetase chromatin binding sites in human mammary cell lines using the DNA adenine methyltransferase identification technology. | 2011 Jun 1 |
2 |
| 22 |
21555910 | The role of holocarboxylase synthetase in genome stability is mediated partly by epigenomic synergies between methylation and biotinylation events. | 2011 Jul |
2 |
| 23 |
21608095 | Site-specific labeling of proteins by using biotin protein ligase conjugated with fluorophores. | 2011 Jun 14 |
2 |
| 24 |
21802411 | Human holocarboxylase synthetase with a start site at methionine-58 is the predominant nuclear variant of this protein and has catalytic activity. | 2011 Aug 19 |
2 |
| 25 |
21930408 | Biotinylation is a natural, albeit rare, modification of human histones. | 2011 Dec |
4 |
| 26 |
19914215 | Substrate recognition characteristics of human holocarboxylase synthetase for biotin ligation. | 2010 Jan 1 |
5 |
| 27 |
20026029 | The polypeptide Syn67 interacts physically with human holocarboxylase synthetase, but is not a target for biotinylation. | 2010 Mar 1 |
2 |
| 28 |
20085763 | The N-terminal domain of human holocarboxylase synthetase facilitates biotinylation via direct interaction with the substrate protein. | 2010 Feb 19 |
2 |
| 29 |
20153287 | Holocarboxylase synthetase: correlation of protein localisation with biological function. | 2010 Apr 1 |
7 |
| 30 |
20357078 | Biotin requirements are lower in human Jurkat lymphoid cells but homeostatic mechanisms are similar to those of HepG2 liver cells. | 2010 Jun |
1 |
| 31 |
20443544 | Structural impact of human and Escherichia coli biotin carboxyl carrier proteins on biotin attachment. | 2010 Jun 8 |
6 |
| 32 |
20592104 | Biotin regulates the expression of holocarboxylase synthetase in the miR-539 pathway in HEK-293 cells. | 2010 Sep |
5 |
| 33 |
19056636 | Sodium-dependent multivitamin transporter gene is regulated at the chromatin level by histone biotinylation in human Jurkat lymphoblastoma cells. | 2009 Jan |
13 |
| 34 |
19056812 | Biotin sensing at the molecular level. | 2009 Jan |
3 |
| 35 |
19157941 | N- and C-terminal domains in human holocarboxylase synthetase participate in substrate recognition. | 2009 Apr |
3 |
| 36 |
19160459 | Nonenzymatic biotinylation of histone H2A. | 2009 Feb |
9 |
| 37 |
19740736 | Distinct amino termini of two human HCS isoforms influence biotin acceptor substrate recognition. | 2009 Nov 6 |
8 |
| 38 |
19812216 | Repression of transposable elements by histone biotinylation. | 2009 Dec |
2 |
| 39 |
17904341 | Holocarboxylase synthetase regulates expression of biotin transporters by chromatin remodeling events at the SMVT locus. | 2008 Jun |
11 |
| 40 |
18429047 | Reduced half-life of holocarboxylase synthetase from patients with severe multiple carboxylase deficiency. | 2008 Jun |
1 |
| 41 |
18442489 | Microbial biotin protein ligases aid in understanding holocarboxylase synthetase deficiency. | 2008 Jul-Aug |
4 |
| 42 |
18845537 | Impaired biotinidase activity disrupts holocarboxylase synthetase expression in late onset multiple carboxylase deficiency. | 2008 Dec 5 |
4 |
| 43 |
19019041 | A novel, enigmatic histone modification: biotinylation of histones by holocarboxylase synthetase. | 2008 Dec |
1 |
| 44 |
19022951 | Biotinylation of histones represses transposable elements in human and mouse cells and cell lines and in Drosophila melanogaster. | 2008 Dec |
2 |
| 45 |
17669049 | Biotin sensing: universal influence of biotin status on transcription. | 2007 |
3 |
| 46 |
16109483 | Lysine residues in N-terminal and C-terminal regions of human histone H2A are targets for biotinylation by biotinidase. | 2006 Apr |
1 |
| 47 |
16359899 | From an inborn error patient to a search for regulatory meaning: a biotin conducted voyage. | 2006 Mar |
3 |
| 48 |
17407983 | Holocarboxylase synthetase deficiency: report of one case. | 2006 Nov-Dec |
4 |
| 49 |
15905112 | Biotin availability regulates expression of the sodium-dependent multivitamin transporter and the rate of biotin uptake in HepG2 cells. | 2005 Aug |
8 |
| 50 |
16134170 | Mutations in the holocarboxylase synthetase gene HLCS. | 2005 Oct |
3 |