Guanine Nucleotides

Rac family small GTPase 1 ; Mus musculus







30 Article(s)
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Pub. Year
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1 35083941 P-Rex2 mediation of synaptic plasticity contributes to bone cancer pain. 2022 Jan-Dec 1
2 34381782 ELMO1 Regulates RANKL-Stimulated Differentiation and Bone Resorption of Osteoclasts. 2021 1
3 32012800 Myoblast Migration and Directional Persistence Affected by Syndecan-4-Mediated Tiam-1 Expression and Distribution. 2020 Jan 27 2
4 32251425 βPix-d promotes tubulin acetylation and neurite outgrowth through a PAK/Stathmin1 signaling pathway. 2020 1
5 33247143 β-Pix-dependent cellular protrusions propel collective mesoderm migration in the mouse embryo. 2020 Nov 27 1
6 30066307 A Novel Synthetic Derivative of Phloroglucinol Inhibits Neuroinflammatory Responses Through Attenuating Kalirin Signaling Pathway in Murine BV2 Microglial Cells. 2019 Apr 1
7 30735546 Involvement of the protein kinase Akt2 in insulin-stimulated Rac1 activation leading to glucose uptake in mouse skeletal muscle. 2019 1
8 31402636 Loss of ϐPix Causes Defects in Early Embryonic Development, and Cell Spreading and PlateletDerived Growth Factor-Induced Chemotaxis in Mouse Embryonic Fibroblasts. 2019 Aug 31 1
9 30177526 Trio GEF mediates RhoA activation downstream of Slit2 and coordinates telencephalic wiring. 2018 Oct 2 1
10 30333726 Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice. 2018 1
11 27617576 Epithelial-mesenchymal transition of ovarian cancer cells is sustained by Rac1 through simultaneous activation of MEK1/2 and Src signaling pathways. 2017 Mar 3
12 29872253 Upregulation of multiple signaling pathways by Dock5 deletion in epithelial cells. 2017 1
13 25917196 Down-regulation of Rac GTPase-activating protein OCRL1 causes aberrant activation of Rac1 in osteoarthritis development. 2015 May 1
14 24628852 Expression and activity of Rac1 is negatively affected in the dehydroepiandrosterone induced polycystic ovary of mouse. 2014 Mar 14 1
15 25025572 Role of the guanine nucleotide exchange factor in Akt2-mediated plasma membrane translocation of GLUT4 in insulin-stimulated skeletal muscle. 2014 Nov 1
16 23852370 Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma. 2013 Sep 1
17 22219288 Dock3 stimulates axonal outgrowth via GSK-3β-mediated microtubule assembly. 2012 Jan 4 1
18 21209221 Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain. 2011 Jan 5 1
19 19995334 Characterization of an mDock5-specific antibody and tissue-specific expression and subcellular localization of mDock5. 2010 Apr 2
20 19458477 Regulation of focal adhesion and cell migration by ANKRD28-DOCK180 interaction. 2009 Jul-Sep 1
21 17196961 Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth. 2007 Feb 15 1
22 15579468 A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death. 2005 Feb 11 1
23 15751964 Tyrosine phosphorylation of adaptor protein 3BP2 induces T cell receptor-mediated activation of transcription factor. 2005 Mar 15 1
24 14988728 Tiam1 mediates neurite outgrowth induced by ephrin-B1 and EphA2. 2004 Mar 10 1
25 12799088 Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain. 2003 Jun 1
26 12935915 Developmental regulation of FERM domain including guanine nucleotide exchange factor gene expression in the mouse brain. 2003 Sep 10 1
27 14550769 Roles of STEF/Tiam1, guanine nucleotide exchange factors for Rac1, in regulation of growth cone morphology. 2003 Sep 2
28 11707441 Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth. 2002 Jan 25 1
29 10998360 Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components. 2000 Oct 1 1
30 10364228 Identification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1. 1999 Jun 18 1