ponatinib

fibroblast growth factor receptor 4 ; Homo sapiens







9 Article(s)
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1 31770593 The role of fibroblast growth factor receptor (FGFR) protein-tyrosine kinase inhibitors in the treatment of cancers including those of the urinary bladder. 2020 Jan 1
2 31128178 Insight into ponatinib resistance mechanisms in rhabdomyosarcoma caused by the mutations in FGFR4 tyrosine kinase using molecular modeling strategies. 2019 Aug 15 1
3 28069043 FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib. 2017 Jan 9 1
4 28094372 Theoretical studies on FGFR isoform selectivity of FGFR1/FGFR4 inhibitors by molecular dynamics simulations and free energy calculations. 2017 Feb 1 2
5 26574622 Antitumor effects and molecular mechanisms of ponatinib on endometrial cancer cells harboring activating FGFR2 mutations. 2016 1
6 25317566 DFG-out mode of inhibition by an irreversible type-1 inhibitor capable of overcoming gate-keeper mutations in FGF receptors. 2015 Jan 16 2
7 25219510 Structural analysis of the human fibroblast growth factor receptor 4 kinase. 2014 Nov 11 2
8 25465127 Structural insights into FGFR kinase isoform selectivity: diverse binding modes of AZD4547 and ponatinib in complex with FGFR1 and FGFR4. 2014 Dec 2 5
9 24124571 Targeting wild-type and mutationally activated FGFR4 in rhabdomyosarcoma with the inhibitor ponatinib (AP24534). 2013 6