Metals

superoxide dismutase 1 ; Homo sapiens







143 Article(s)
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51 25052939 Protein charge ladders reveal that the net charge of ALS-linked superoxide dismutase can be different in sign and magnitude from predicted values. 2014 Oct 1
52 25056685 Metal-substituted zeolitic imidazolate framework ZIF-108: gas-sorption and membrane-separation properties. 2014 Sep 1 2
53 25100994 The potential for transition metal-mediated neurodegeneration in amyotrophic lateral sclerosis. 2014 1
54 25410708 Effect of including torsional parameters for histidine-metal interactions in classical force fields for metalloproteins. 2014 Nov 20 1
55 25429517 In-cell NMR reveals potential precursor of toxic species from SOD1 fALS mutants. 2014 Nov 27 1
56 23291526 Mechanical probes of SOD1 predict systematic trends in metal and dimer affinity of ALS-associated mutants. 2013 Mar 11 1
57 23306896 Metal-based biologically active compounds: synthesis, characterization, DNA interaction, antibacterial, cytotoxic and SOD mimic activities. 2013 Feb 1
58 23431152 SOD1 exhibits allosteric frustration to facilitate metal binding affinity. 2013 Mar 5 2
59 23431167 Global structural motions from the strain of a single hydrogen bond. 2013 Mar 5 1
60 23801010 A 4 + 4 strategy for synthesis of zeolitic metal-organic frameworks: an indium-MOF with SOD topology as a light-harvesting antenna. 2013 Dec 11 2
61 23844996 Local unfolding and aggregation mechanisms of SOD1: a Monte Carlo exploration. 2013 Aug 8 2
62 23871896 Effect of metal loading and subcellular pH on net charge of superoxide dismutase-1. 2013 Nov 15 3
63 24026444 The role of solvent exclusion in the interaction between D124 and the metal site in SOD1: implications for ALS. 2013 Dec 4
64 24070210 Copper complexes of bioactive ligands with superoxide dismutase activity. 2013 Nov 1
65 24379756 An emerging role for misfolded wild-type SOD1 in sporadic ALS pathogenesis. 2013 Dec 16 2
66 22092237 Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer. 2012 Jan 11 1
67 22332887 A novel variant of human superoxide dismutase 1 harboring amyotrophic lateral sclerosis-associated and experimental mutations in metal-binding residues and free cysteines lacks toxicity in vivo. 2012 May 2
68 22542526 Early steps in oxidation-induced SOD1 misfolding: implications for non-amyloid protein aggregation in familial ALS. 2012 Aug 24 1
69 22899264 Separation and characterization of superoxide dismutase 1 (SOD-1) from human erythrocytes by capillary electrophoresis time-of-flight mass spectrometry. 2012 Aug 1
70 21196222 Mechanisms of oxidative DNA damage induced by carcinogenic arylamines. 2011 Jan 1 1
71 21549128 ALS-causing SOD1 mutations promote production of copper-deficient misfolded species. 2011 Jun 24 1
72 21722094 The structural plasticity of the human copper chaperone for SOD1: insights from combined size-exclusion chromatographic and solution X-ray scattering studies. 2011 Oct 1 1
73 19837190 Post-translational modifications of superoxide dismutase. 2010 Feb 1
74 20045652 Square pyramidal copper(II) complexes with forth generation fluoroquinolone and neutral bidentate ligand: structure, antibacterial, SOD mimic and DNA-interaction studies. 2010 Feb 1
75 20052996 Characterization of a covalent polysulfane bridge in copper-zinc superoxide dismutase . 2010 Feb 16 1
76 20184893 Disulfide-reduced ALS variants of Cu, Zn superoxide dismutase exhibit increased populations of unfolded species. 2010 Apr 30 2
77 20188129 Development of liposome-based mimics of superoxide dismutase and peroxidase based on the "LIPOzyme" concept. 2010 May 3 1
78 20404910 Metal-free ALS variants of dimeric human Cu,Zn-superoxide dismutase have enhanced populations of monomeric species. 2010 Apr 9 2
79 20485746 Unveiling the unfolding pathway of FALS associated G37R SOD1 mutant: a computational study. 2010 Jun 1
80 20709807 A novel SOD1 splice site mutation associated with familial ALS revealed by SOD activity analysis. 2010 Nov 1 1
81 18951903 Unfolding and folding kinetics of amyotrophic lateral sclerosis-associated mutant Cu,Zn superoxide dismutases. 2009 Jan 9 1
82 19063897 Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis. 2009 Feb 6 1
83 19196430 Mutant copper-zinc superoxide dismutase associated with amyotrophic lateral sclerosis binds to adenine/uridine-rich stability elements in the vascular endothelial growth factor 3'-untranslated region. 2009 Feb 1
84 19289127 The structure of human extracellular copper-zinc superoxide dismutase at 1.7 A resolution: insights into heparin and collagen binding. 2009 May 1 1
85 19369197 Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants. 2009 Apr 28 2
86 19635794 A common property of amyotrophic lateral sclerosis-associated variants: destabilization of the copper/zinc superoxide dismutase electrostatic loop. 2009 Nov 6 2
87 19639152 Structural characterization of a highly active superoxide-dismutase mimic. 2009 Aug 21 1
88 19651777 Metal deficiency increases aberrant hydrophobicity of mutant superoxide dismutases that cause amyotrophic lateral sclerosis. 2009 Oct 2 2
89 19805550 Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded beta-barrel at physiological temperature. 2009 Dec 4 2
90 19828437 Transient structural distortion of metal-free Cu/Zn superoxide dismutase triggers aberrant oligomerization. 2009 Oct 27 1
91 18301754 SOD1 and amyotrophic lateral sclerosis: mutations and oligomerization. 2008 Feb 27 2
92 18761352 Denaturational stress induces formation of zinc-deficient monomers of Cu,Zn superoxide dismutase: implications for pathogenesis in amyotrophic lateral sclerosis. 2008 Nov 7 1
93 18826240 Metalation states versus enzyme activities of Cu, Zn-superoxide dismutase probed by electrospray ionization mass spectrometry. 2008 Nov 1 1
94 19052230 Dynamical roles of metal ions and the disulfide bond in Cu, Zn superoxide dismutase folding and aggregation. 2008 Dec 16 4
95 17292965 Roles of exogenous divalent metals in the nucleolytic activity of Cu,Zn superoxide dismutase. 2007 Apr 2
96 17381088 Binding of a single zinc ion to one subunit of copper-zinc superoxide dismutase apoprotein substantially influences the structure and stability of the entire homodimeric protein. 2007 Apr 18 1
97 17548825 Molecular dynamics using atomic-resolution structure reveal structural fluctuations that may lead to polymerization of human Cu-Zn superoxide dismutase. 2007 Jun 12 3
98 17592131 Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. 2007 Jul 3 3
99 17683122 Metalation of the amyotrophic lateral sclerosis mutant glycine 37 to arginine superoxide dismutase (SOD1) apoprotein restores its structural and dynamical properties in solution to those of metalated wild-type SOD1. 2007 Sep 4 1
100 16291742 Human SOD1 before harboring the catalytic metal: solution structure of copper-depleted, disulfide-reduced form. 2006 Jan 27 1