Disulfides

superoxide dismutase 1 ; Homo sapiens







100 Article(s)
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51 24279864 Ligand noninnocence of thiolate/disulfide in dinuclear copper complexes: solvent-dependent redox isomerization and proton-coupled electron transfer. 2013 Dec 18 2
52 22219129 Oxidative modification of cysteine 111 promotes disulfide bond-independent aggregation of SOD1. 2012 Apr 2
53 22471402 Interaction of cisplatin with human superoxide dismutase. 2012 Apr 25 1
54 22595939 Identification of a novel Cys146X mutation of SOD1 in familial amyotrophic lateral sclerosis by whole-exome sequencing. 2012 Sep 1
55 22651090 Redox properties of the disulfide bond of human Cu,Zn superoxide dismutase and the effects of human glutaredoxin 1. 2012 Aug 15 12
56 22869735 Human superoxide dismutase 1 (hSOD1) maturation through interaction with human copper chaperone for SOD1 (hCCS). 2012 Aug 21 2
57 23118898 Role of disulfide cross-linking of mutant SOD1 in the formation of inclusion-body-like structures. 2012 4
58 23339308 SOD1 aggregation and ALS: role of metallation states and disulfide status. 2012 2
59 21257910 Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS. 2011 Feb 8 1
60 21865594 Mia40-dependent oxidation of cysteines in domain I of Ccs1 controls its distribution between mitochondria and the cytosol. 2011 Oct 1
61 21930926 Intermolecular transmission of superoxide dismutase 1 misfolding in living cells. 2011 Sep 27 3
62 20184893 Disulfide-reduced ALS variants of Cu, Zn superoxide dismutase exhibit increased populations of unfolded species. 2010 Apr 30 1
63 20367259 Import, maturation, and function of SOD1 and its copper chaperone CCS in the mitochondrial intermembrane space. 2010 Nov 1 3
64 20412382 Superoxide dismutase-1 and other proteins in inclusions from transgenic amyotrophic lateral sclerosis model mice. 2010 Jul 1
65 20499289 Expression, purification, bioactivity, and partial characterization of a recombinant human bone morphogenetic protein-7 produced in human 293T cells. 2010 Oct 1
66 20595380 Cu,Zn superoxide dismutase maturation and activity are regulated by COMMD1. 2010 Sep 10 1
67 20600836 A ditryptophan cross-link is responsible for the covalent dimerization of human superoxide dismutase 1 during its bicarbonate-dependent peroxidase activity. 2010 Sep 15 2
68 19227972 Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q. 2009 Apr 21 1
69 19325915 Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase. 2009 2
70 19586921 The right to choose: multiple pathways for activating copper,zinc superoxide dismutase. 2009 Sep 11 1
71 19651777 Metal deficiency increases aberrant hydrophobicity of mutant superoxide dismutases that cause amyotrophic lateral sclerosis. 2009 Oct 2 3
72 19788901 Expression of human Cu, Zn-superoxide dismutase in an insect cell-free system and its structural analysis by MALDI-TOF MS. 2009 Dec 2
73 18316367 A limited role for disulfide cross-linking in the aggregation of mutant SOD1 linked to familial amyotrophic lateral sclerosis. 2008 May 16 4
74 18385137 The folding of human active and inactive extracellular superoxide dismutases is an intracellular event. 2008 May 30 2
75 18552350 Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis. 2008 Aug 29 3
76 18703498 Different regulation of wild-type and mutant Cu,Zn superoxide dismutase localization in mammalian mitochondria. 2008 Nov 1 1
77 19052230 Dynamical roles of metal ions and the disulfide bond in Cu, Zn superoxide dismutase folding and aggregation. 2008 Dec 16 5
78 16291742 Human SOD1 before harboring the catalytic metal: solution structure of copper-depleted, disulfide-reduced form. 2006 Jan 27 1
79 16624935 Overloading of stable and exclusion of unstable human superoxide dismutase-1 variants in mitochondria of murine amyotrophic lateral sclerosis models. 2006 Apr 19 1
80 16644738 Local unfolding in a destabilized, pathogenic variant of superoxide dismutase 1 observed with H/D exchange and mass spectrometry. 2006 Jun 30 1
81 16771675 Posttranslational modifications in Cu,Zn-superoxide dismutase and mutations associated with amyotrophic lateral sclerosis. 2006 May-Jun 5
82 16828895 Activation of superoxide dismutases: putting the metal to the pedal. 2006 Jul 3
83 16880213 The effects of glutaredoxin and copper activation pathways on the disulfide and stability of Cu,Zn superoxide dismutase. 2006 Sep 29 4
84 15691826 Amyotrophic lateral sclerosis mutations have the greatest destabilizing effect on the apo- and reduced form of SOD1, leading to unfolding and oxidative aggregation. 2005 Apr 29 6
85 16081415 SIRPbeta1 is expressed as a disulfide-linked homodimer in leukocytes and positively regulates neutrophil transepithelial migration. 2005 Oct 28 2
86 16909016 Mutant SOD1 instability: implications for toxicity in amyotrophic lateral sclerosis. 2005 2
87 15109247 An intersubunit disulfide bond prevents in vitro aggregation of a superoxide dismutase-1 mutant linked to familial amytrophic lateral sclerosis. 2004 May 4 1
88 15326189 The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status. 2004 Nov 12 1
89 15485869 Dissociation of human copper-zinc superoxide dismutase dimers using chaotrope and reductant. Insights into the molecular basis for dimer stability. 2004 Dec 24 4
90 15518578 The structure of rabbit extracellular superoxide dismutase differs from the human protein. 2004 Nov 9 1
91 15522970 Folding of human superoxide dismutase: disulfide reduction prevents dimerization and produces marginally stable monomers. 2004 Nov 9 3
92 14623191 Folding of Cu, Zn superoxide dismutase and familial amyotrophic lateral sclerosis. 2003 Nov 28 2
93 11698397 Thiol oxidase activity of copper, zinc superoxide dismutase. 2002 Jan 18 1
94 12398152 Beneficial and harmful effects of thiols. 2002 May-Jun 2
95 10077638 Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1. 1999 Mar 16 1
96 7541042 Binding stoichiometry of the cytotoxic T lymphocyte-associated molecule-4 (CTLA-4). A disulfide-linked homodimer binds two CD86 molecules. 1995 Jun 23 1
97 7727388 The disulfide linkages and glycosylation sites of the human natriuretic peptide receptor-C homodimer. 1994 Sep 20 2
98 8493557 GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. 1993 May 21 1
99 1390878 The influence of medium components on Cu(2+)-dependent oxidation of low-density lipoproteins and its sensitivity to superoxide dismutase. 1992 Sep 22 1
100 2050696 Identification of the disulfide-linked homodimer of apolipoprotein E3 in plasma. Impact on receptor binding activity. 1991 Jun 25 3