Arachidonic Acid

phospholipase A2, group IVA (cytosolic, calcium-dependent) ; Mus musculus







116 Article(s)
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1 35281932 Dapagliflozin Reduces Apoptosis of Diabetic Retina and Human Retinal Microvascular Endothelial Cells Through ERK1/2/cPLA2/AA/ROS Pathway Independent of Hypoglycemic. 2022 2
2 35370678 Gypenoside L and Gypenoside LI Inhibit Proliferation in Renal Cell Carcinoma via Regulation of the MAPK and Arachidonic Acid Metabolism Pathways. 2022 1
3 35450754 Inhibiting the Cytosolic Phospholipase A2-Arachidonic Acid Pathway With Arachidonyl Trifluoromethyl Ketone Attenuates Radiation-Induced Lung Fibrosis. 2022 Apr 18 3
4 33569432 Renal tubular injury induced by glyphosate combined with hard water: the role of cytosolic phospholipase A2. 2021 Jan 1
5 34420370 6β-Hydroxytestosterone Promotes Angiotensin II-Induced Hypertension via Enhanced Cytosolic Phospholipase A2α Activity. 2021 Sep 1
6 34942197 Epidermal Fatty Acid‒Binding Protein Mediates Depilatory-Induced Acute Skin Inflammation. 2021 Dec 21 2
7 32152223 Two- and three-color STORM analysis reveals higher-order assembly of leukotriene synthetic complexes on the nuclear envelope of murine neutrophils. 2020 Apr 24 2
8 33022884 Integrative analysis of hepatic metabolomic and transcriptomic data reveals potential mechanism of nonalcoholic steatohepatitis in high-fat diet-fed mice. 2020 Oct 6 1
9 31080170 Synthesis of oxidized phospholipids by sn-1 acyltransferase using 2-15-HETE lysophospholipids. 2019 Jun 28 1
10 30557348 cPLA2α-/- sympathetic neurons exhibit increased membrane excitability and loss of N-Type Ca2+ current inhibition by M1 muscarinic receptor signaling. 2018 1
11 27771900 RhoA/Rho Kinase Mediates Neuronal Death Through Regulating cPLA2 Activation. 2017 Nov 1
12 28444900 Lactosylceramide-Induced Phosphorylation Signaling to Group IVA Phospholipase A2 via Reactive Oxygen Species in Tumor Necrosis Factor-α-Treated Cells. 2017 Dec 1
13 28851448 Dietary arachidonic acid increases deleterious effects of amyloid-β oligomers on learning abilities and expression of AMPA receptors: putative role of the ACSL4-cPLA2 balance. 2017 Aug 29 2
14 26045535 Cytosolic Phospholipase A2α Is Essential for Renal Dysfunction and End-Organ Damage Associated With Angiotensin II-Induced Hypertension. 2016 Feb 1
15 26653747 Potentiation of endothelin-1-induced prostaglandin E2 formation by Ni(2+) and Sr(2+) in murine osteoblastic MC3T3-E1 cells. 2016 Jan 1
16 27316329 Leptin suppresses adenosine triphosphate-induced impairment of spinal cord astrocytes. 2016 Oct 1
17 27335109 Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer. 2016 Aug 15 1
18 27501951 Cytosolic phospholipase A2 contributes to innate immune defense against Candida albicans lung infection. 2016 Aug 8 1
19 27769509 The Roles of the Secreted Phospholipase A2 Gene Family in Immunology. 2016 1
20 25460828 The role of PGE2 in intestinal inflammation and tumorigenesis. 2015 Jan-Mar 1
21 25497453 Comparative biochemical characterization of the monoacylglycerol lipase inhibitor KML29 in brain, spinal cord, liver, spleen, fat and muscle tissue. 2015 Apr 2
22 25504011 Molecular characterisation of group IVA (cytosolic) phospholipase A2 in murine osteoblastic MC3T3-E1 cells. 2015 Feb 1
23 25667212 Cytosolic phospholipase A2α is critical for angiotensin II-induced hypertension and associated cardiovascular pathophysiology. 2015 Apr 5
24 25969996 Study of the role of cytosolic phospholipase A2 alpha in eicosanoid generation and thymocyte maturation in the thymus. 2015 1
25 26143945 AKT and cytosolic phospholipase A2α form a positive loop in prostate cancer cells. 2015 2
26 26520095 Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway. 2015 Oct 31 2
27 24121057 Genetic ablation of 12/15-lipoxygenase but not 5-lipoxygenase protects against denervation-induced muscle atrophy. 2014 Feb 2
28 24297180 Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation. 2014 Jan 17 2
29 24337743 Cytosolic group IVA and calcium-independent group VIA phospholipase A2s act on distinct phospholipid pools in zymosan-stimulated mouse peritoneal macrophages. 2014 Jan 15 2
30 24501374 Long-term potentiation at cerebellar parallel fiber-Purkinje cell synapses requires presynaptic and postsynaptic signaling cascades. 2014 Feb 5 1
31 24529827 Transient postnatal fluoxetine leads to decreased brain arachidonic acid metabolism and cytochrome P450 4A in adult mice. 2014 May 4
32 24623140 Cytosolic phospholipase A2 protein as a novel therapeutic target for spinal cord injury. 2014 May 2
33 24673159 The fish oil ingredient, docosahexaenoic acid, activates cytosolic phospholipase A₂ via GPR120 receptor to produce prostaglandin E₂ and plays an anti-inflammatory role in macrophages. 2014 Sep 1
34 23160182 Metabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo. 2013 Feb 1
35 23307660 Retrograde cPLA2α/arachidonic acid/2-AG signaling is essential for cerebellar depolarization-induced suppression of excitation and long-term potentiation. 2013 Jun 5
36 23376443 Leptin attenuates lipopolysaccharide-induced apoptosis of thymocytes partially via down-regulation of cPLA2 and p38 MAPK activation. 2013 Mar 1
37 24244531 Eicosanoid profiling in an orthotopic model of lung cancer progression by mass spectrometry demonstrates selective production of leukotrienes by inflammatory cells of the microenvironment. 2013 2
38 24293010 (S)-tetrahydroisoquinoline alkaloid inhibits LPS-induced arachidonic acid release through downregulation of cPLA2 expression. 2013 Nov 1
39 22188721 Critical role of cPLA2 in Aβ oligomer-induced neurodegeneration and memory deficit. 2012 Jun 2
40 22427514 Disruption of group IVA cytosolic phospholipase A(2) attenuates myocardial ischemia-reperfusion injury partly through inhibition of TNF-α-mediated pathway. 2012 May 15 1
41 22727501 Glutamine suppresses dinitrophenol fluorobenzene-induced allergic contact dermatitis and itching: inhibition of contact dermatitis by glutamine. 2012 Aug 1
42 22766077 Anti-inflammatory mechanism of action of azithromycin in LPS-stimulated J774A.1 cells. 2012 Oct 1
43 22927908 Cytosolic phospholipase A2 alpha/arachidonic acid signaling mediates depolarization-induced suppression of excitation in the cerebellum. 2012 3
44 22965852 Chronic treatment with anti-bipolar drugs causes intracellular alkalinization in astrocytes, altering their functions. 2012 Nov 1
45 21350197 Cytosolic phospholipase A2alpha contributes to blood pressure increases and endothelial dysfunction under chronic NO inhibition. 2011 May 1
46 21454644 CD36 protein is involved in store-operated calcium flux, phospholipase A2 activation, and production of prostaglandin E2. 2011 May 20 1
47 21703211 Cytosolic phospholipase A(2)α protects against Fas- but not LPS-induced liver injury. 2011 Dec 1
48 21746963 Cytosolic phospholipase A2α blockade abrogates disease during the tissue-damage effector phase of experimental autoimmune encephalomyelitis by its action on APCs. 2011 Aug 15 1
49 20133605 Lipid signaling in cytosolic phospholipase A2alpha-cyclooxygenase-2 cascade mediates cerebellar long-term depression and motor learning. 2010 Feb 16 1
50 20226226 Localization and function of cytosolic phospholipase A2alpha at the Golgi. 2010 Jun 1