| 1 |
34662731 | Steady-state kinetic analysis of human cholinesterases over wide concentration ranges of competing substrates. | 2022 Jan |
2 |
| 2 |
29663860 | Novel coumarin derivatives as potent acetylcholinesterase inhibitors: insight into efficacy, mode and site of inhibition. | 2019 Apr |
1 |
| 3 |
30411689 | Spirocyclohexadienones as an Uncommon Scaffold for Acetylcholinesterase Inhibitory Activity. | 2019 |
1 |
| 4 |
30890752 | Conjugates of methylene blue with γ-carboline derivatives as new multifunctional agents for the treatment of neurodegenerative diseases. | 2019 Mar 19 |
2 |
| 5 |
30928873 | New benzyl pyridinium derivatives bearing 2,4-dioxochroman moiety as potent agents for treatment of Alzheimer's disease: Design, synthesis, biological evaluation, and docking study. | 2019 Jun |
1 |
| 6 |
31271946 | Development of pyrazole and spiropyrazoline analogs as multifunctional agents for treatment of Alzheimer's disease. | 2019 Sep |
1 |
| 7 |
28617100 | Discovery of potent and selective acetylcholinesterase (AChE) inhibitors: acacetin 7-O-methyl ether Mannich base derivatives synthesised from easy access natural product naringin. | 2018 Mar |
1 |
| 8 |
29775949 | Design and synthesis of some new carboxamide and propanamide derivatives bearing phenylpyridazine as a core ring and the investigation of their inhibitory potential on in-vitro acetylcholinesterase and butyrylcholinesterase. | 2018 Sep |
1 |
| 9 |
29886321 | Rational design of carbamate-based dual binding site and central AChE inhibitors by a "biooxidisable" prodrug approach: Synthesis, in vitro evaluation and docking studies. | 2018 Jul 15 |
1 |
| 10 |
29980922 | Influence of gauche effect on uncharged oxime reactivators for the reactivation of tabun-inhibited AChE: quantum chemical and steered molecular dynamics studies. | 2018 Jul |
1 |
| 11 |
30257474 | Molecular Modeling Studies on the Interactions of Aflatoxin B1 and Its Metabolites with Human Acetylcholinesterase. Part II: Interactions with the Catalytic Anionic Site (CAS). | 2018 Sep 25 |
2 |
| 12 |
27766908 | Synthesis and molecular docking studies of some 4-phthalimidobenzenesulfonamide derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors. | 2017 Dec |
2 |
| 13 |
27801600 | Tertiary amine derivatives of chlorochalcone as acetylcholinesterase (AChE) and buthylcholinesterase (BuChE) inhibitors: the influence of chlorine, alkyl amine side chain and α,β-unsaturated ketone group. | 2017 Dec |
1 |
| 14 |
27863370 | Novel tacrine-1,2,3-triazole hybrids: In vitro, in vivo biological evaluation and docking study of cholinesterase inhibitors. | 2017 Jan 5 |
1 |
| 15 |
28374576 | Docking-based design and synthesis of galantamine-camphane hybrids as inhibitors of acetylcholinesterase. | 2017 Nov |
3 |
| 16 |
28492309 | Competitive Inhibition Mechanism of Acetylcholinesterase without Catalytic Active Site Interaction: Study on Functionalized C60 Nanoparticles via in Vitro and in Silico Assays. | 2017 Jun 7 |
1 |
| 17 |
28646405 | Revealing the importance of linkers in K-series oxime reactivators for tabun-inhibited AChE using quantum chemical, docking and SMD studies. | 2017 Aug |
1 |
| 18 |
28963904 | Design, synthesis and biological evaluation of 1,3-dihydroxyxanthone derivatives: Effective agents against acetylcholinesterase. | 2017 Dec |
2 |
| 19 |
26752094 | Design, synthesis and evaluation of novel 7-aminoalkyl-substituted flavonoid derivatives with improved cholinesterase inhibitory activities. | 2016 Feb 15 |
1 |
| 20 |
27214510 | Synthesis and anticholinesterase activity of coumarin-3-carboxamides bearing tryptamine moiety. | 2016 Oct 4 |
1 |
| 21 |
27392529 | Novel series of tacrine-tianeptine hybrids: Synthesis, cholinesterase inhibitory activity, S100B secretion and a molecular modeling approach. | 2016 Oct 4 |
1 |
| 22 |
27492242 | Docking-based Design of Galantamine Derivatives with Dual-site Binding to Acetylcholinesterase. | 2016 Jul |
1 |
| 23 |
27910192 | Novel Tacrine-Based Pyrano[3',4':5,6]pyrano[2,3-b]quinolinones: Synthesis and Cholinesterase Inhibitory Activity. | 2016 Dec |
1 |
| 24 |
26579427 | Design, synthesis and evaluation of genistein-polyamine conjugates as multi-functional anti-Alzheimer agents. | 2015 Jan |
1 |
| 25 |
26639720 | Macrocyclic derivatives of 6-methyluracil: New ligands of the peripheral anionic site of acetylcholinesterase. | 2015 |
6 |
| 26 |
26639721 | Molecular modeling of mechanism of action of anti-myasthenia gravis slow-binding inhibitor of acetylcholinesterase. | 2015 |
1 |
| 27 |
23981668 | A new motif in the N-terminal of acetylcholinesterase triggers amyloid-β aggregation and deposition. | 2014 Jan |
1 |
| 28 |
24628027 | Acetylcholinesterase inhibitors with photoswitchable inhibition of β-amyloid aggregation. | 2014 May 21 |
3 |
| 29 |
22975155 | Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates. | 2013 Mar 25 |
1 |
| 30 |
23353586 | Identification of potential bivalent inhibitors from natural compounds for acetylcholinesterase through in silico screening using multiple pharmacophores. | 2013 Mar |
5 |
| 31 |
23515568 | Research on the regulation of the spatial structure of acetylcholinesterase tetramer with high efficiency by AFM. | 2013 |
2 |
| 32 |
23984975 | Divergent structure-activity relationships of structurally similar acetylcholinesterase inhibitors. | 2013 Oct 10 |
1 |
| 33 |
24475704 | [Design, synthesis and evaluation of bis-nicotine derivatives as inhibitors of cholinesterases and beta-amyloid aggregation]. | 2013 Nov |
1 |
| 34 |
22467516 | Design, synthesis and evaluation of novel 2-(aminoalkyl)-isoindoline-1,3-dione derivatives as dual-binding site acetylcholinesterase inhibitors. | 2012 Jul |
1 |
| 35 |
23062825 | Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. | 2012 Nov 15 |
1 |
| 36 |
21211982 | Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation. | 2011 Jan 15 |
1 |
| 37 |
21397996 | Benzophenone-based derivatives: a novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. | 2011 May |
2 |
| 38 |
21570330 | Binding conformation prediction between human acetylcholinesterase and cytochrome c using molecular modeling methods. | 2011 Aug |
2 |
| 39 |
22229321 | Human platelet acetylcholinesterase inhibition by cyclophosphamide: a combined experimental and computational approach. | 2011 Dec |
1 |
| 40 |
20056426 | Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors. | 2010 Feb |
1 |
| 41 |
20823602 | Design, synthesis and evaluation of difunctionalized 4-hydroxybenzaldehyde derivatives as novel cholinesterase inhibitors. | 2010 Sep |
1 |
| 42 |
19051205 | Investigations into the development of catalytic activity in anti-acetylcholinesterase idiotypic and anti-idiotypic antibodies. | 2009 May-Jun |
1 |
| 43 |
17359933 | Acetylcholinesterase modulates neurite outgrowth on fibronectin. | 2007 May 4 |
3 |
| 44 |
17005406 | New multipotent tetracyclic tacrines with neuroprotective activity. | 2006 Dec 15 |
2 |
| 45 |
15974895 | Acetylcholinesterase-amyloid-beta-peptide interaction: effect of Congo Red and the role of the Wnt pathway. | 2005 Jul |
1 |
| 46 |
15034934 | Functional idiotypic mimicry of an adhesion- and differentiation-promoting site on acetylcholinesterase. | 2004 Apr 1 |
1 |
| 47 |
15483114 | Excessive expression of acetylcholinesterase impairs glutamatergic synaptogenesis in hippocampal neurons. | 2004 Oct 13 |
2 |
| 48 |
11904227 | Substrate activation in acetylcholinesterase induced by low pH or mutation in the pi-cation subsite. | 2002 Feb 11 |
2 |
| 49 |
11523986 | A structural motif of acetylcholinesterase that promotes amyloid beta-peptide fibril formation. | 2001 Sep 4 |
1 |
| 50 |
10619655 | Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase. | 1999 Nov 26 |
2 |