20 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 35462163 | Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease. | 2022 Jul 5 | 1 |
2 | 34327619 | Machine learning models for predicting the activity of AChE and BACE1 dual inhibitors for the treatment of Alzheimer's disease. | 2021 Jul 29 | 2 |
3 | 31901380 | Selective acetylcholinesterase inhibitors derived from muscle relaxant dantrolene. | 2020 Feb 15 | 1 |
4 | 30784883 | Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease. | 2019 Apr 1 | 2 |
5 | 31585263 | Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments. | 2019 Dec | 1 |
6 | 29421570 | Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates. | 2018 Mar 10 | 2 |
7 | 27914796 | Design and synthesis of new piperidone grafted acetylcholinesterase inhibitors. | 2017 Jan 15 | 2 |
8 | 28610432 | QSAR model for prediction of the therapeutic potency of N-benzylpiperidine derivatives as AChE inhibitors. | 2017 Jun | 4 |
9 | 28841514 | A novel class of thiosemicarbazones show multi-functional activity for the treatment of Alzheimer's disease. | 2017 Oct 20 | 1 |
10 | 27402296 | New neurogenic lipoic-based hybrids as innovative Alzheimer's drugs with σ-1 agonism and β-secretase inhibition. | 2016 Jul | 2 |
11 | 24211638 | Novel coumarin-3-carboxamides bearing N-benzylpiperidine moiety as potent acetylcholinesterase inhibitors. | 2013 | 3 |
12 | 21074294 | Receptor-dependent (RD) 3D-QSAR approach of a series of benzylpiperidine inhibitors of human acetylcholinesterase (HuAChE). | 2011 Jan | 2 |
13 | 15892689 | Human acetylcholinesterase inhibitors: electronic-topological and neural network approaches to the structure-activity relationships study. | 2005 May | 2 |
14 | 10733609 | Validation of protein-based alignment in 3D quantitative structure-activity relationships with CoMFA models. | 2000 Jan | 2 |
15 | 11256231 | Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. | 2000 Oct | 1 |
16 | 10067428 | [Discovery and development of donepezil hydrochloride for the treatment of Alzheimer's disease]. | 1999 Feb | 1 |
17 | 8558505 | A comparative molecular field analysis study of N-benzylpiperidines as acetylcholinesterase inhibitors. | 1996 Jan 19 | 1 |
18 | 8894101 | The rationale for E2020 as a potent acetylcholinesterase inhibitor. | 1996 Sep | 1 |
19 | 1738151 | QSAR analyses of the substituted indanone and benzylpiperidine rings of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase. | 1992 Feb 7 | 3 |
20 | 1738152 | Conformational analyses and molecular-shape comparisons of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase. | 1992 Feb 7 | 1 |