| 1 |
35489467 | Theoretical assessment of the performances of commercial oximes on the reactivation of acetylcholinesterase inhibited by the nerve agent A-242 (novichok). | 2022 Jul |
2 |
| 2 |
34353435 | Acetylcholinesterase and human cancers. | 2021 |
2 |
| 3 |
34820662 | Poisoning by organophosphorus nerve agents and pesticides: An overview of the principle strategies and current progress of mass spectrometry-based procedures for verification. | 2021 Jan |
2 |
| 4 |
32305437 | Structural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A. | 2020 Jul |
1 |
| 5 |
32992925 | Solvent Deuterium Oxide Isotope Effects on the Reactions of Organophosphorylated Acetylcholinesterase. | 2020 Sep 25 |
1 |
| 6 |
31138650 | Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase. | 2019 Jul 5 |
2 |
| 7 |
31175846 | Rate-limiting step in the decarbamoylation of acetylcholinesterases with large carbamoyl groups. | 2019 Aug 1 |
2 |
| 8 |
31675671 | A new series of pyridazinone derivatives as cholinesterases inhibitors: Synthesis, in vitro activity and molecular modeling studies. | 2019 Dec |
1 |
| 9 |
29870665 | Demonstration of In Vitro Resurrection of Aged Acetylcholinesterase after Exposure to Organophosphorus Chemical Nerve Agents. | 2018 Aug 23 |
2 |
| 10 |
30096649 | Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase. | 2018 Sep 5 |
3 |
| 11 |
30098983 | Decarbamoylation of acetylcholinesterases is markedly slowed as carbamoyl groups increase in size. | 2018 Oct 1 |
2 |
| 12 |
30110162 | Resurrection Biology: Aged Acetylcholinesterase Brought Back to Life. | 2018 Aug 23 |
1 |
| 13 |
27311923 | New insights on molecular interactions of organophosphorus pesticides with esterases. | 2017 Feb 1 |
1 |
| 14 |
28061690 | Organophosphorus Xenobiotic Toxicology. | 2017 Jan 6 |
1 |
| 15 |
28892361 | Immunopurification of Acetylcholinesterase from Red Blood Cells for Detection of Nerve Agent Exposure. | 2017 Oct 16 |
4 |
| 16 |
29137457 | Monoclonal Antibody That Recognizes Diethoxyphosphotyrosine-Modified Proteins and Peptides Independent of Surrounding Amino Acids. | 2017 Dec 18 |
2 |
| 17 |
25743373 | Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches. | 2016 Mar |
4 |
| 18 |
27040140 | Butyrylcholinesterase as a Diagnostic and Therapeutic Target for Alzheimer's Disease. | 2016 |
2 |
| 19 |
27055524 | A mechanism-based 3D-QSAR approach for classification and prediction of acetylcholinesterase inhibitory potency of organophosphate and carbamate analogs. | 2016 Apr |
2 |
| 20 |
27101948 | Oxime-mediated in vitro reactivation kinetic analysis of organophosphates-inhibited human and electric eel acetylcholinesterase. | 2016 Jun |
2 |
| 21 |
27109753 | Relationships of human α/β hydrolase fold proteins and other organophosphate-interacting proteins. | 2016 Nov 25 |
1 |
| 22 |
27371941 | Limitations in current acetylcholinesterase structure-based design of oxime antidotes for organophosphate poisoning. | 2016 Aug |
3 |
| 23 |
24805972 | Oxime-dipeptides as anticholinesterase, reactivator of phosphonylated-serine of AChE catalytic triad: probing the mechanistic insight by MM-GBSA, dynamics simulations and DFT analysis. | 2015 |
1 |
| 24 |
25407587 | Molecular modeling and in vitro reactivation study between the oxime BI-6 and acetylcholinesterase inhibited by different nerve agents. | 2015 Sep |
2 |
| 25 |
25441834 | Development and Structural Modifications of Cholinesterase Reactivators against Chemical Warfare Agents in Last Decade: A Review. | 2015 |
2 |
| 26 |
25874456 | A wrench in the works of human acetylcholinesterase: soman induced conformational changes revealed by molecular dynamics simulations. | 2015 |
1 |
| 27 |
26520174 | Novel and selective acetylcholinesterase inhibitors for Tetranychus cinnabarinus (Acari: Tetranychidae). | 2015 Nov |
1 |
| 28 |
26563788 | Organophosphorus and carbamate insecticide poisoning. | 2015 |
1 |
| 29 |
24652148 | V-type nerve agents phosphonylate ubiquitin at biologically relevant lysine residues and induce intramolecular cyclization by an isopeptide bond. | 2014 Aug |
1 |
| 30 |
23111374 | Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents. | 2013 Mar 25 |
2 |
| 31 |
23376121 | Catalytic-site conformational equilibrium in nerve-agent adducts of acetylcholinesterase: possible implications for the HI-6 antidote substrate specificity. | 2013 May 1 |
2 |
| 32 |
23631528 | Designed amphiphilic β-sheet peptides as templates for paraoxon adsorption and detection. | 2013 Jun 11 |
2 |
| 33 |
23679855 | Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase. | 2013 Aug 1 |
1 |
| 34 |
23747845 | A first principles investigation of aging processes in soman conjugated AChE. | 2013 Aug 25 |
1 |
| 35 |
24040835 | The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity. | 2013 Oct 22 |
1 |
| 36 |
22280344 | Novel and viable acetylcholinesterase target site for developing effective and environmentally safe insecticides. | 2012 Apr |
1 |
| 37 |
22703537 | Effect of different oximes on rat and human cholinesterases inhibited by methamidophos: a comparative in vitro and in silico study. | 2012 Dec |
2 |
| 38 |
22984913 | Aging mechanism of soman inhibited acetylcholinesterase. | 2012 Oct 11 |
1 |
| 39 |
21605992 | Probing the reactivation process of sarin-inhibited acetylcholinesterase with α-nucleophiles: hydroxylamine anion is predicted to be a better antidote with DFT calculations. | 2011 Aug |
1 |
| 40 |
20408548 | Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation. | 2010 May 27 |
1 |
| 41 |
20882513 | Chromatographic analysis of toxic phosphylated oximes (POX): a brief overview. | 2010 Oct |
2 |
| 42 |
19194505 | Selective and irreversible inhibitors of aphid acetylcholinesterases: steps toward human-safe insecticides. | 2009 |
2 |
| 43 |
19536291 | Structure of HI-6*sarin-acetylcholinesterase determined by X-ray crystallography and molecular dynamics simulation: reactivator mechanism and design. | 2009 Jun 18 |
2 |
| 44 |
19761810 | Reactivation of tabun-hAChE investigated by structurally analogous oximes and mutagenesis. | 2009 Nov 30 |
2 |
| 45 |
18501885 | Interactions of butane, but-2-ene or xylene-like linked bispyridinium para-aldoximes with native and tabun-inhibited human cholinesterases. | 2008 Sep 25 |
1 |
| 46 |
18565503 | Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes. | 2008 Sep 25 |
2 |
| 47 |
18975951 | Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation. | 2008 Nov 26 |
2 |
| 48 |
17698511 | Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry. | 2007 Nov |
2 |
| 49 |
16341717 | Molecular docking study on the "back door" hypothesis for product clearance in acetylcholinesterase. | 2006 Feb |
1 |
| 50 |
16403852 | Concentration-dependent kinetics of acetylcholinesterase inhibition by the organophosphate paraoxon. | 2006 Apr |
2 |