Donepezil

acetylcholinesterase (Cartwright blood group) ; Homo sapiens







333 Article(s)
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151 24081314 Drugs for cognitive loss and dementia. 2013 Oct 1
152 24092978 Domperidone effective in preventing rivastigmine-related gastrointestinal disturbances in patients with Alzheimer's disease. 2013 1
153 24097403 Structural analysis of 2-arylidene-1-indanone derivatives by electrospray ionization tandem mass spectrometry. 2013 Nov 15 2
154 24145276 A case report on the use of an acetylcholinesterase inhibitor (donepezil) in traumatic brain injury. 2013 Aug 2
155 24211638 Novel coumarin-3-carboxamides bearing N-benzylpiperidine moiety as potent acetylcholinesterase inhibitors. 2013 1
156 24379961 Synthesis and Evaluation of Anti-acetylcholinesterase Activity of 2-(2-(4-(2-Oxo-2-phenylethyl)piperazin-1-yl) ethyl)Isoindoline-1,3-dione Derivatives with Potential Anti-Alzheimer Effects. 2013 Oct 1
157 21666432 Greater responsiveness to donepezil in Alzheimer patients with higher levels of acetylcholinesterase based on attention task scores and a donepezil PET study. 2012 Apr-Jun 2
158 21901320 The scopolamine model as a pharmacodynamic marker in early drug development. 2012 Mar 1
159 22238217 Toxicity and efficacy of the acetylcholinesterase (AChe) inhibitor donepezil in childhood brain tumor survivors: a pilot study. 2012 Sep 4
160 22245641 Changes in regional cerebral blood flow and functional connectivity in the cholinergic pathway associated with cognitive performance in subjects with mild Alzheimer's disease after 12-week donepezil treatment. 2012 Apr 2 1
161 22427467 [Achetylcholinesterase (AChE) inhibition and serum lipokines in Alzheimer's disease: friend or foe?]. 2012 Mar 1
162 22465999 Replication study to confirm the role of CYP2D6 polymorphism rs1080985 on donepezil efficacy in Alzheimer's disease patients. 2012 1
163 22534665 Synthesis of new indole derivatives structurally related to donepezil and their biological evaluation as acetylcholinesterase inhibitors. 2012 Apr 25 3
164 22561476 Successful treatment of musical hallucinations with the acetylcholinesterase inhibitor donepezil. 2012 Jun 1
165 22595038 Cognitive effects of the acetylcholinesterase inhibitor, donepezil, in healthy, non-treatment seeking smokers: a pilot feasibility study. 2012 Nov 1 1
166 22691879 Influences of donepezil on cardiovascular system--possible therapeutic benefits for heart failure--donepezil cardiac test registry (DOCTER) study. 2012 Sep 1
167 22692245 Synthesis and biological evaluation of thiophene derivatives as acetylcholinesterase inhibitors. 2012 Jun 12 1
168 22832236 Cholinergic deficit and response to donepezil therapy in Parkinson's disease with dementia. 2012 5
169 22915447 Donepezil in Parkinson's disease dementia: a randomized, double-blind efficacy and safety study. 2012 Sep 1 1
170 23035744 Structures of human acetylcholinesterase in complex with pharmacologically important ligands. 2012 Nov 26 3
171 23279148 Donepezil-induced sleep spindle in a patient with dementia with Lewy bodies: a case report. 2012 Dec 1
172 23372236 Safety and efficacy of donepezil hydrochloride in patients with mild to moderate Alzheimer's disease: Findings of an observational study. 2012 Oct 1
173 24052808 Synthesis and in silico evaluation of 1N-methyl-1S-methyl-2-nitroethylene (NMSM) derivatives against Alzheimer disease: to understand their interacting mechanism with acetylcholinesterase. 2012 3
174 20880294 Changes in CSF acetyl- and butyrylcholinesterase activity after long-term treatment with AChE inhibitors in Alzheimer's disease. 2011 Aug 3
175 21299848 Progressive cholinergic decline in Alzheimer's Disease: consideration for treatment with donepezil 23 mg in patients with moderate to severe symptomatology. 2011 Feb 7 1
176 21621811 Synthesis and biological activity of derivatives of tetrahydroacridine as acetylcholinesterase inhibitors. 2011 Aug 1
177 21699076 Design, synthesis and biological evaluation of new 2-benzoxazolinone derivatives as potential cholinesterase inhibitors for therapy of alzheimer's disease. 2011 Jun 1
178 21772691 Donepezil: A cause of inadequate muscle relaxation and delayed neuromuscular recovery. 2011 Apr 1
179 22161694 Effects of donepezil on cognitive performance after sleep deprivation. 2011 Dec 1
180 19836169 Donepezil treatment and the subjective effects of intravenous cocaine in dependent individuals. 2010 Feb 1 3
181 19935404 Estimation of plasma IC50 of donepezil for cerebral acetylcholinesterase inhibition in patients with Alzheimer disease using positron emission tomography. 2010 Mar-Apr 11
182 19962381 Donepezil, an acetylcholinesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic hindlimb model. 2010 Apr 2
183 20193764 Acetylcholinesterase inhibitors and memantine for neuroenhancement in healthy individuals: a systematic review. 2010 Jun 1
184 20196555 Virtual screening discovery of new acetylcholinesterase inhibitors issued from CERMN chemical library. 2010 Mar 22 1
185 20401964 Use of a novel radiometric method to assess the inhibitory effect of donepezil on acetylcholinesterase activity in minimally diluted tissue samples. 2010 Apr 2
186 20422942 Bioequivalence study of two different tablet formulations of donepezil using truncated areas under the curve. A single-center, single-dose, randomized, open-label, 2-way crossover study under fasting conditions. 2010 2
187 20522977 Donepezil, a potent acetylcholinesterase inhibitor, induces caspase-dependent apoptosis in human promyelocytic leukemia HL-60 cells. 2010 3
188 20664535 The effect of donepezil treatment on cardiovascular mortality. 2010 Sep 1
189 21116228 Synthesis of benzofuran derivatives via rearrangement and their inhibitory activity on acetylcholinesterase. 2010 Nov 29 1
190 18780301 Variability of AChE, BChE, and ChAT genes in the late-onset form of Alzheimer's disease and relationships with response to treatment with Donepezil and Rivastigmine. 2009 Jun 5 1
191 19199870 Different cholinesterase inhibitor effects on CSF cholinesterases in Alzheimer patients. 2009 Feb 3
192 19262966 Methodological improvements in quantifying cognitive change in clinical trials: an example with single-dose administration of donepezil. 2009 Mar 1
193 19286462 Quantitative analysis of donepezil binding to acetylcholinesterase using positron emission tomography and [5-(11)C-methoxy]donepezil. 2009 Jul 1 6
194 19363262 Acute but not chronic donepezil increases muscarinic receptor-mediated signaling via arachidonic acid in unanesthetized rats. 2009 2
195 19388874 Donepezil (aricept) as a treatment for anorexia nervosa: a very feasible therapeutic possibility. 2009 May 1
196 19494441 Effects of chronic donepezil treatment and cholinergic deafferentation on parietal pyramidal neuron morphology. 2009 1
197 19573265 High occupancy of sigma1 receptors in the human brain after single oral administration of donepezil: a positron emission tomography study using [11C]SA4503. 2009 Sep 2
198 19580698 Increase of SCF plasma concentration during donepezil treatment of patients with early Alzheimer's disease. 2009 Nov 1
199 17990049 Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer's disease. 2008 Mar 1
200 18070217 In vivo visualization of donepezil binding in the brain of patients with Alzheimer's disease. 2008 Apr 9