| 1 |
33054569 | Molecular networking based dereplication of AChE inhibitory compounds from the medicinal plant Vincetoxicum funebre (Boiss. & Kotschy). | 2022 Mar |
2 |
| 2 |
34893996 | Design and synthesis of novel chalcone derivatives and evaluation of their inhibitory activities against acetylcholinesterase. | 2022 Mar |
1 |
| 3 |
34931332 | Design, synthesis, biological activity, molecular docking, and molecular dynamics of novel benzimidazole derivatives as potential AChE/MAO-B dual inhibitors. | 2022 Mar |
1 |
| 4 |
35098414 | Alzheimer's disease therapy based on acetylcholinesterase inhibitor/blocker effects on voltage-gated potassium channels. | 2022 Mar |
2 |
| 5 |
35221376 | Synthesis, kinetic evaluation and molecular docking studies of donepezil-based acetylcholinesterase inhibitors. | 2022 Jan 5 |
2 |
| 6 |
35408519 | Design, Synthesis, and Evaluation of Novel 2H-Benzo[b][1,4]thiazin-3(4H)-one Derivatives as New Acetylcholinesterase Inhibitors. | 2022 Mar 25 |
1 |
| 7 |
35462163 | Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease. | 2022 Jul 5 |
1 |
| 8 |
35462270 | A single-molecule with multiple investigations: Synthesis, characterization, computational methods, inhibitory activity against Alzheimer's disease, toxicity, and ADME studies. | 2022 Apr 18 |
2 |
| 9 |
35595404 | Pharmacogenetic studies in Alzheimer disease. | 2022 May |
1 |
| 10 |
32752941 | Exploring 3-Benzyloxyflavones as new lead cholinesterase inhibitors: synthesis, structure-activity relationship and molecular modelling simulations. | 2021 Oct |
1 |
| 11 |
33100197 | Enhancing Therapeutic Efficacy of Donepezil by Combined Therapy: A Comprehensive Review. | 2021 |
1 |
| 12 |
33230575 | Donepezil induces ventricular arrhythmias by delayed repolarisation. | 2021 Mar |
1 |
| 13 |
33416315 | Dual Effect of Prussian Blue Nanoparticles on Aβ40 Aggregation: β-Sheet Fibril Reduction and Copper Dyshomeostasis Regulation. | 2021 Feb 8 |
2 |
| 14 |
33478277 | Discovery of new acetylcholinesterase inhibitors for Alzheimer's disease: virtual screening and in vitro characterisation. | 2021 Dec |
1 |
| 15 |
33540879 | Anti-Cholinesterase Combination Drug Therapy as a Potential Treatment for Alzheimer's Disease. | 2021 Feb 2 |
2 |
| 16 |
33809771 | Novel Donepezil-Arylsulfonamide Hybrids as Multitarget-Directed Ligands for Potential Treatment of Alzheimer's Disease. | 2021 Mar 16 |
1 |
| 17 |
33844597 | Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition. | 2021 Apr |
1 |
| 18 |
33915501 | Potential therapeutic natural products against Alzheimer's disease with Reference of Acetylcholinesterase. | 2021 Jul |
1 |
| 19 |
34078793 | [Donepezil Reduces Amyloid Precursor Protein Endocytosis by Resulting from Increase in the Expression of Sorting Nexin Protein 33]. | 2021 |
2 |
| 20 |
34121977 | Novel 1,2,4-oxadiazole derivatives as selective butyrylcholinesterase inhibitors: Design, synthesis and biological evaluation. | 2021 |
3 |
| 21 |
34198150 | Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE/GSK3β inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine. | 2021 Nov 5 |
1 |
| 22 |
34337258 | Synthesis and Biological Evaluation of Thiazole-Based Derivatives as Potential Acetylcholinesterase Inhibitors. | 2021 Jul 27 |
2 |
| 23 |
34363318 | Structural Fractal Analysis of the Active Site of Acetylcholinesterase in Complexes with Huperzine A, Galantamine, and Donepezil. | 2021 Nov |
2 |
| 24 |
34522196 | Design, synthesis, and bio-evaluation of new isoindoline-1,3-dione derivatives as possible inhibitors of acetylcholinesterase. | 2021 Oct |
2 |
| 25 |
34549134 | Pd-Catalyzed Direct Modification of an Anti-Alzheimer's Disease Drug: Synthesis and Biological Evaluation of α-Aryl Donepezil Analogues. | 2021 Sep 14 |
2 |
| 26 |
34714861 | Association between human paraoxonase 2 protein and efficacy of acetylcholinesterase inhibiting drugs used against Alzheimer's disease. | 2021 |
1 |
| 27 |
34755546 | Synthesis, molecular modeling and cholinesterase inhibitory effects of 2-indolinone-based hydrazinecarbothioamides. | 2021 Dec |
1 |
| 28 |
34911424 | Anti-Neurodegenerative Benefits of Acetylcholinesterase Inhibitors in Alzheimer's Disease: Nexus of Cholinergic and Nerve Growth Factor Dysfunction. | 2021 |
2 |
| 29 |
32096991 | Donepezil Inhibits Acetylcholinesterase via Multiple Binding Modes at Room Temperature. | 2020 Jul 27 |
5 |
| 30 |
32098407 | Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease. | 2020 Feb 22 |
1 |
| 31 |
32174113 | Donepezil Prevents ox-LDL-Induced Attachment of THP-1 Monocytes to Human Aortic Endothelial Cells (HAECs). | 2020 Apr 20 |
1 |
| 32 |
32184102 | Inhibition of acetylcholinesterase attenuated retinal inflammation via suppressing NF-κB activation. | 2020 Jun |
1 |
| 33 |
32356584 | Design, Synthesis and Bioevaluation of Two Series of 3-[(1-Benzyl-1H-1,2,3-triazol-4-yl)methyl]quinazolin-4(3H)-ones and N-(1-Benzylpiperidin-4-yl)quinazolin-4-amines. | 2020 Jul |
2 |
| 34 |
32414155 | Improving Anti-Neurodegenerative Benefits of Acetylcholinesterase Inhibitors in Alzheimer's Disease: Are Irreversible Inhibitors the Future? | 2020 May 13 |
1 |
| 35 |
32443670 | MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer's Disease Therapy. | 2020 May 20 |
4 |
| 36 |
32454110 | The inefficacy of donepezil on glycated-AChE inhibition: Binding affinity, complex stability and mechanism. | 2020 Oct 1 |
11 |
| 37 |
32874532 | QT interval prolongation and Torsades de Pointes with donepezil, rivastigmine and galantamine. | 2020 |
1 |
| 38 |
32942070 | Discovery of methoxy-naphthyl linked N-(1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase. | 2020 Dec 1 |
1 |
| 39 |
32955256 | Discovery of a New Donepezil-like Acetylcholinesterase Inhibitor for Targeting Alzheimer's Disease: Computational Studies with Biological Validation. | 2020 Oct 26 |
2 |
| 40 |
32986667 | Novel Hybrid Acetylcholinesterase Inhibitors Induce Differentiation and Neuritogenesis in Neuronal Cells in vitro Through Activation of the AKT Pathway. | 2020 |
1 |
| 41 |
33042734 | A Novel Targeted and High-Efficiency Nanosystem for Combinational Therapy for Alzheimer's Disease. | 2020 Oct |
2 |
| 42 |
33058916 | Donepezil in the treatment of ischemic stroke: Review and future perspective. | 2020 Dec 15 |
1 |
| 43 |
33061904 | Association Between Peripheral Adiponectin and Lipids Levels and the Therapeutic Response to Donepezil Treatment in Han Chinese Patients With Alzheimer's Disease. | 2020 |
2 |
| 44 |
33327436 | The Cholinesterase Inhibitory Properties of Stephaniae Tetrandrae Radix. | 2020 Dec 14 |
1 |
| 45 |
33375412 | First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease. | 2020 Dec 27 |
2 |
| 46 |
33488178 | Combined ligand and structure-based virtual screening approaches for identification of novel AChE inhibitors. | 2020 |
1 |
| 47 |
29663860 | Novel coumarin derivatives as potent acetylcholinesterase inhibitors: insight into efficacy, mode and site of inhibition. | 2019 Apr |
2 |
| 48 |
29768996 | A Systematic Review on Donepezil-based Derivatives as Potential Cholinesterase Inhibitors for Alzheimer's Disease. | 2019 |
1 |
| 49 |
30372021 | Classics in Chemical Neuroscience: Donepezil. | 2019 Jan 16 |
1 |
| 50 |
30378536 | Donepezil decreases heart rate in elderly patients with Alzheimer's disease. | 2019 Feb |
1 |