Organophosphonates

acetylcholinesterase (Cartwright blood group) ; Homo sapiens







16 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 32702607 No promising antidote 25 years after the Tokyo subway sarin attack: A review. 2020 Nov 2
2 32992925 Solvent Deuterium Oxide Isotope Effects on the Reactions of Organophosphorylated Acetylcholinesterase. 2020 Sep 25 1
3 22982773 A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds. 2013 Mar 25 1
4 20189400 Synthesis and kinetic analysis of some phosphonate analogs of cyclophostin as inhibitors of human acetylcholinesterase. 2010 Mar 15 1
5 19536291 Structure of HI-6*sarin-acetylcholinesterase determined by X-ray crystallography and molecular dynamics simulation: reactivator mechanism and design. 2009 Jun 18 3
6 18821801 Synthesis and biological evaluation of a phosphonate analog of the natural acetyl cholinesterase inhibitor cyclophostin. 2008 Nov 7 1
7 17382909 Kinetic analysis of reactivation and aging of human acetylcholinesterase inhibited by different phosphoramidates. 2007 Jun 1 1
8 16429526 Acetylcholinesterase mutants: oxime-assisted catalytic scavengers of organophosphonates. 2005 Dec 15 1
9 10653663 Evidence for P-N bond scission in phosphoroamidate nerve agent adducts of human acetylcholinesterase. 2000 Feb 8 1
10 8718893 Aspartate 74 as a primary determinant in acetylcholinesterase governing specificity to cationic organophosphonates. 1996 Aug 20 1
11 7619798 Origins and diversity of the aging reaction in phosphonate adducts of serine hydrolase enzymes: what characteristics of the active site do they probe? 1995 Jul 18 2
12 1890690 Phosphylation kinetic constants and oxime-induced reactivation in acetylcholinesterase from fetal bovine serum, bovine caudate nucleus, and electric eel. 1991 Sep 1
13 2037866 Competitive irreversible inhibition of enzymes in the presence of a substrate: scope and limitations. 1991 1
14 2362084 Oxime-induced reactivation of acetylcholinesterase inhibited by organophosphinates. 1990 Apr 2
15 3783578 Nonquaternary cholinesterase reactivators. 3. 3(5)-Substituted 1,2,4-oxadiazol-5(3)-aldoximes and 1,2,4-oxadiazole-5(3)-thiocarbohydroximates as reactivators of organophosphonate-inhibited eel and human acetylcholinesterase in vitro. 1986 Nov 1
16 566114 Fluorescent phosphonate label for serine hydrolases, pyrenebutyl methylphosphonofluoridate: reaction with acetylcholinesterase. 1978 May 2 1