| 201 |
18548743 | Eight new bispyridinium oximes in comparison with the conventional oximes pralidoxime and obidoxime: in vivo efficacy to protect from diisopropylfluorophosphate toxicity. | 2008 Oct |
2 |
| 202 |
18555982 | Comparison of oxime reactivation and aging of nerve agent-inhibited monkey and human acetylcholinesterases. | 2008 Sep 25 |
3 |
| 203 |
18564794 | Adjuncts and alternatives to oxime therapy in organophosphate poisoning--is there evidence of benefit in human poisoning? A review. | 2008 May |
1 |
| 204 |
18565503 | Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes. | 2008 Sep 25 |
1 |
| 205 |
18617161 | Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro. | 2008 Sep 25 |
3 |
| 206 |
18855728 | The development of new oximes and the evaluation of their reactivating, therapeutic and neuroprotective efficacy against tabun. | 2008 Oct |
1 |
| 207 |
16904807 | Simulation of cholinesterase status at different scenarios of nerve agent exposure. | 2007 Apr 20 |
7 |
| 208 |
16904808 | Evaluation of HI 6 treatment after percutaneous VR exposure by use of a kinetic-based dynamic computer model. | 2007 Apr 20 |
4 |
| 209 |
16904809 | Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase. | 2007 Apr 20 |
5 |
| 210 |
16962227 | Evaluation of monoquaternary pyridinium oximes potency to reactivate tabun-inhibited human acetylcholinesterase. | 2007 Apr 20 |
3 |
| 211 |
17010492 | Testing of antidotes for organophosphorus compounds: experimental procedures and clinical reality. | 2007 Apr 20 |
1 |
| 212 |
17112559 | Recent advances in evaluation of oxime efficacy in nerve agent poisoning by in vitro analysis. | 2007 Mar |
3 |
| 213 |
17196318 | Acetylcholinesterase: converting a vulnerable target to a template for antidotes and detection of inhibitor exposure. | 2007 Apr 20 |
3 |
| 214 |
17265452 | In vitro oxime reactivation of red blood cell acetylcholinesterase inhibited by methyl-paraoxon. | 2007 Mar-Apr |
1 |
| 215 |
17298091 | Oxime-induced reactivation of sarin-inhibited AChE: a theoretical mechanisms study. | 2007 Mar 8 |
2 |
| 216 |
17370251 | Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro. | 2007 Nov-Dec |
5 |
| 217 |
17382909 | Kinetic analysis of reactivation and aging of human acetylcholinesterase inhibited by different phosphoramidates. | 2007 Jun 1 |
4 |
| 218 |
17383875 | Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase. | 2007 Jun 1 |
1 |
| 219 |
17443135 | Novel nerve-agent antidote design based on crystallographic and mass spectrometric analyses of tabun-conjugated acetylcholinesterase in complex with antidotes. | 2007 Sep |
3 |
| 220 |
17456837 | Unequal efficacy of pyridinium oximes in acute organophosphate poisoning. | 2007 Mar |
3 |
| 221 |
17504181 | Treatment of organophosphate intoxication using cholinesterase reactivators: facts and fiction. | 2007 May |
3 |
| 222 |
17900152 | An in vitro comparative study on the reactivation of nerve agent-inhibited guinea pig and human acetylcholinesterases by oximes. | 2007 Oct 23 |
4 |
| 223 |
17913691 | Red blood cell acetylcholinesterase and plasma butyrylcholinesterase status: important indicators for the treatment of patients poisoned by organophosphorus compounds. | 2007 Sep |
2 |
| 224 |
18220560 | Cholinesterase reactivators: the fate and effects in the organism poisoned with organophosphates/nerve agents. | 2007 Dec |
2 |
| 225 |
18254274 | Evaluation of potency of known oximes (pralidoxime, trimedoxime, HI-6, methoxime, obidoxime) to in vitro reactivate acetylcholinesterase inhibited by pesticides (chlorpyrifos and methylchlorpyrifos) and nerve agent (Russian VX). | 2007 |
1 |
| 226 |
16193529 | Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon. | 2006 Jan-Feb |
1 |
| 227 |
16515465 | Structural requirements of acetylcholinesterase reactivators. | 2006 Mar |
2 |
| 228 |
16623863 | Russian VX: inhibition and reactivation of acetylcholinesterase compared with VX agent. | 2006 Apr |
2 |
| 229 |
16720069 | Analysis of inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds with human and pig acetylcholinesterase. | 2006 Jul 5 |
1 |
| 230 |
16740352 | Application of kinetic-based computer modelling to evaluate the efficacy of HI 6 in percutaneous VX poisoning. | 2006 Jul 5 |
6 |
| 231 |
16971069 | Hydrolysis of an acetylthiocholine by pralidoxime iodide (2-PAM). | 2006 Oct 25 |
1 |
| 232 |
16982122 | Pretreatment with pyridinium oximes improves antidotal therapy against tabun poisoning. | 2006 Nov 10 |
4 |
| 233 |
17194020 | New group of xylene linker-containing acetylcholinesterase reactivators as antidotes against the nerve agent cyclosarin. | 2006 Oct |
2 |
| 234 |
17194021 | Synthesis, characterization and inhibitory potency of two oxono and thiono analogues of phosphoramidate compounds on acetylcholinesterase. | 2006 Oct |
1 |
| 235 |
17252938 | Potency of new structurally different oximes to reactivate cyclosarin-inhibited human brain acetylcholinesterases. | 2006 Dec |
2 |
| 236 |
17288495 | Development of the bisquaternary oxime HI-6 toward clinical use in the treatment of organophosphate nerve agent poisoning. | 2006 |
2 |
| 237 |
17288500 | The role of oximes in the treatment of nerve agent poisoning in civilian casualties. | 2006 |
1 |
| 238 |
17438836 | Reactivation potency of new group of acetylcholinesterase reactivators and their comparison with currently available oximes. | 2006 |
2 |
| 239 |
18072133 | Reactivation of sarin-inhibited pig brain acetylcholinesterase using oxime antidotes. | 2006 Dec |
1 |
| 240 |
15654704 | Oximes for acute organophosphate pesticide poisoning. | 2005 Jan 25 |
1 |
| 241 |
15904945 | Evaluation of oxime efficacy in nerve agent poisoning: development of a kinetic-based dynamic model. | 2005 Dec 15 |
4 |
| 242 |
16119192 | In vitro reactivation of sarin-inhibited brain acetylcholinesterase from different species by various oximes. | 2005 Jun |
1 |
| 243 |
16119193 | A new group of monoquaternary reactivators of acetylcholinesterase inhibited by nerve agents. | 2005 Jun |
1 |
| 244 |
16167316 | Effect of metoclopramide and ranitidine on the inhibition of human AChE by VX in vitro. | 2005 Nov-Dec |
4 |
| 245 |
16263103 | Correlation between red blood cell acetylcholinesterase activity and neuromuscular transmission in organophosphate poisoning. | 2005 Dec 15 |
1 |
| 246 |
16266695 | Estimation of oxime efficacy in nerve agent poisoning: a kinetic approach. | 2005 Dec 15 |
8 |
| 247 |
16293236 | Bioscavengers for the protection of humans against organophosphate toxicity. | 2005 Dec 15 |
1 |
| 248 |
16429518 | Comparison of ability of some oximes to reactivate sarin-inhibited brain acetylcholinesterase from different species. | 2005 Dec 15 |
2 |
| 249 |
16429526 | Acetylcholinesterase mutants: oxime-assisted catalytic scavengers of organophosphonates. | 2005 Dec 15 |
1 |
| 250 |
14647978 | Reactivation and aging kinetics of human acetylcholinesterase inhibited by organophosphonylcholines. | 2004 Apr |
2 |