Oximes

acetylcholinesterase (Cartwright blood group) ; Homo sapiens







304 Article(s)
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201 18548743 Eight new bispyridinium oximes in comparison with the conventional oximes pralidoxime and obidoxime: in vivo efficacy to protect from diisopropylfluorophosphate toxicity. 2008 Oct 2
202 18555982 Comparison of oxime reactivation and aging of nerve agent-inhibited monkey and human acetylcholinesterases. 2008 Sep 25 3
203 18564794 Adjuncts and alternatives to oxime therapy in organophosphate poisoning--is there evidence of benefit in human poisoning? A review. 2008 May 1
204 18565503 Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes. 2008 Sep 25 1
205 18617161 Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro. 2008 Sep 25 3
206 18855728 The development of new oximes and the evaluation of their reactivating, therapeutic and neuroprotective efficacy against tabun. 2008 Oct 1
207 16904807 Simulation of cholinesterase status at different scenarios of nerve agent exposure. 2007 Apr 20 7
208 16904808 Evaluation of HI 6 treatment after percutaneous VR exposure by use of a kinetic-based dynamic computer model. 2007 Apr 20 4
209 16904809 Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase. 2007 Apr 20 5
210 16962227 Evaluation of monoquaternary pyridinium oximes potency to reactivate tabun-inhibited human acetylcholinesterase. 2007 Apr 20 3
211 17010492 Testing of antidotes for organophosphorus compounds: experimental procedures and clinical reality. 2007 Apr 20 1
212 17112559 Recent advances in evaluation of oxime efficacy in nerve agent poisoning by in vitro analysis. 2007 Mar 3
213 17196318 Acetylcholinesterase: converting a vulnerable target to a template for antidotes and detection of inhibitor exposure. 2007 Apr 20 3
214 17265452 In vitro oxime reactivation of red blood cell acetylcholinesterase inhibited by methyl-paraoxon. 2007 Mar-Apr 1
215 17298091 Oxime-induced reactivation of sarin-inhibited AChE: a theoretical mechanisms study. 2007 Mar 8 2
216 17370251 Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro. 2007 Nov-Dec 5
217 17382909 Kinetic analysis of reactivation and aging of human acetylcholinesterase inhibited by different phosphoramidates. 2007 Jun 1 4
218 17383875 Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase. 2007 Jun 1 1
219 17443135 Novel nerve-agent antidote design based on crystallographic and mass spectrometric analyses of tabun-conjugated acetylcholinesterase in complex with antidotes. 2007 Sep 3
220 17456837 Unequal efficacy of pyridinium oximes in acute organophosphate poisoning. 2007 Mar 3
221 17504181 Treatment of organophosphate intoxication using cholinesterase reactivators: facts and fiction. 2007 May 3
222 17900152 An in vitro comparative study on the reactivation of nerve agent-inhibited guinea pig and human acetylcholinesterases by oximes. 2007 Oct 23 4
223 17913691 Red blood cell acetylcholinesterase and plasma butyrylcholinesterase status: important indicators for the treatment of patients poisoned by organophosphorus compounds. 2007 Sep 2
224 18220560 Cholinesterase reactivators: the fate and effects in the organism poisoned with organophosphates/nerve agents. 2007 Dec 2
225 18254274 Evaluation of potency of known oximes (pralidoxime, trimedoxime, HI-6, methoxime, obidoxime) to in vitro reactivate acetylcholinesterase inhibited by pesticides (chlorpyrifos and methylchlorpyrifos) and nerve agent (Russian VX). 2007 1
226 16193529 Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon. 2006 Jan-Feb 1
227 16515465 Structural requirements of acetylcholinesterase reactivators. 2006 Mar 2
228 16623863 Russian VX: inhibition and reactivation of acetylcholinesterase compared with VX agent. 2006 Apr 2
229 16720069 Analysis of inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds with human and pig acetylcholinesterase. 2006 Jul 5 1
230 16740352 Application of kinetic-based computer modelling to evaluate the efficacy of HI 6 in percutaneous VX poisoning. 2006 Jul 5 6
231 16971069 Hydrolysis of an acetylthiocholine by pralidoxime iodide (2-PAM). 2006 Oct 25 1
232 16982122 Pretreatment with pyridinium oximes improves antidotal therapy against tabun poisoning. 2006 Nov 10 4
233 17194020 New group of xylene linker-containing acetylcholinesterase reactivators as antidotes against the nerve agent cyclosarin. 2006 Oct 2
234 17194021 Synthesis, characterization and inhibitory potency of two oxono and thiono analogues of phosphoramidate compounds on acetylcholinesterase. 2006 Oct 1
235 17252938 Potency of new structurally different oximes to reactivate cyclosarin-inhibited human brain acetylcholinesterases. 2006 Dec 2
236 17288495 Development of the bisquaternary oxime HI-6 toward clinical use in the treatment of organophosphate nerve agent poisoning. 2006 2
237 17288500 The role of oximes in the treatment of nerve agent poisoning in civilian casualties. 2006 1
238 17438836 Reactivation potency of new group of acetylcholinesterase reactivators and their comparison with currently available oximes. 2006 2
239 18072133 Reactivation of sarin-inhibited pig brain acetylcholinesterase using oxime antidotes. 2006 Dec 1
240 15654704 Oximes for acute organophosphate pesticide poisoning. 2005 Jan 25 1
241 15904945 Evaluation of oxime efficacy in nerve agent poisoning: development of a kinetic-based dynamic model. 2005 Dec 15 4
242 16119192 In vitro reactivation of sarin-inhibited brain acetylcholinesterase from different species by various oximes. 2005 Jun 1
243 16119193 A new group of monoquaternary reactivators of acetylcholinesterase inhibited by nerve agents. 2005 Jun 1
244 16167316 Effect of metoclopramide and ranitidine on the inhibition of human AChE by VX in vitro. 2005 Nov-Dec 4
245 16263103 Correlation between red blood cell acetylcholinesterase activity and neuromuscular transmission in organophosphate poisoning. 2005 Dec 15 1
246 16266695 Estimation of oxime efficacy in nerve agent poisoning: a kinetic approach. 2005 Dec 15 8
247 16293236 Bioscavengers for the protection of humans against organophosphate toxicity. 2005 Dec 15 1
248 16429518 Comparison of ability of some oximes to reactivate sarin-inhibited brain acetylcholinesterase from different species. 2005 Dec 15 2
249 16429526 Acetylcholinesterase mutants: oxime-assisted catalytic scavengers of organophosphonates. 2005 Dec 15 1
250 14647978 Reactivation and aging kinetics of human acetylcholinesterase inhibited by organophosphonylcholines. 2004 Apr 2