Oximes

acetylcholinesterase (Cartwright blood group) ; Homo sapiens







304 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
151 21730071 Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging. 2011 Aug 26 2
152 21799476 New experimental Oximes in the management of organophosphorus pesticides poisoning. 2011 Dec 1
153 21803135 Restoration of nerve agent inhibited muscle force production in human intercostal muscle strips with HI 6. 2011 Sep 25 2
154 21930118 Reactivation of organophosphate-inhibited human acetylcholinesterase by isonitrosoacetone (MINA): a kinetic analysis. 2011 Nov 15 2
155 21983245 Potential of two new oximes in reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by organophosphate compounds: an in vitro study. 2011 Dec 5
156 19883634 Paradox findings may challenge orthodox reasoning in acute organophosphate poisoning. 2010 Sep 6 3
157 19917271 Evaluation of medical countermeasures against organophosphorus compounds: the value of experimental data and computer simulations. 2010 Sep 6 7
158 20004171 Butyrylcholinesterase for protection from organophosphorus poisons: catalytic complexities and hysteretic behavior. 2010 Feb 15 1
159 20005727 Bisquaternary pyridinium oximes: Comparison of in vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase. 2010 Jan 15 3
160 20028185 In silico pharmacophore model for tabun-inhibited acetylcholinesterase reactivators: a study of their stereoelectronic properties. 2010 Jan 9
161 20105433 Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship? 2010 Sep 6 1
162 20156534 Comparative study of oxime-induced reactivation of erythrocyte and muscle AChE from different animal species following inhibition by sarin or paraoxon. 2010 May 4 4
163 20192902 Oxime K027: novel low-toxic candidate for the universal reactivator of nerve agent- and pesticide-inhibited acetylcholinesterase. 2010 Aug 1
164 20202777 Hydrophobicity/hydrophilicity descriptors obtained from extrapolated chromatographic retention data as modeling tools for biological distribution: application to some oxime-type acetylcholinesterase reactivators. 2010 Aug 1 2
165 20345348 Interaction of nerve agent antidotes with cholinergic systems. 2010 1
166 20347021 Chromatographic preparation and kinetic analysis of interactions between tabun enantiomers and acetylcholinesterase. 2010 Jun 2 1
167 20402654 Novel acetylcholinesterase reactivator--oxime K048--reactivation activity in vitro. 2010 Jan 2
168 20406208 In vitro reactivating effects of standard and newly developed oximes on malaoxon-inhibited mouse brain acetylcholinesterase. 2010 Sep 1
169 20412789 Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase. 2010 Sep 6 6
170 20417629 Interactions of pyridinium oximes with acetylcholinesterase. 2010 Sep 6 4
171 20433814 Comparison of human and guinea pig acetylcholinesterase sequences and rates of oxime-assisted reactivation. 2010 Sep 6 1
172 20510679 Kinetic analysis of interactions between alkylene-linked bis-pyridiniumaldoximes and human acetylcholinesterases inhibited by various organophosphorus compounds. 2010 Sep 15 1
173 20542100 Pharmacokinetics of obidoxime in patients poisoned with organophosphorus compounds. 2010 Sep 1 2
174 20546883 Passive diffusion of acetylcholinesterase oxime reactivators through the blood-brain barrier: influence of molecular structure. 2010 Sep 1
175 20600799 In vitro evaluation of bis-pyridinium oximes bearing methoxy alkane linker as reactivators of sarin inhibited human acetylcholinesterase. 2010 Sep 1
176 20635332 Pharmacokinetics and pharmacodynamics of some oximes and associated therapeutic consequences: a critical review. 2010 Nov 1
177 20888357 Reactivation of organophosphate-inhibited human, Cynomolgus monkey, swine and guinea pig acetylcholinesterase by MMB-4: a modified kinetic approach. 2010 Dec 15 1
178 20929049 Pharmacological agents in the prophylaxis/treatment of organophosphorous pesticide intoxication. 2010 Jul 1
179 21151975 Nanoparticulate transport of oximes over an in vitro blood-brain barrier model. 2010 Dec 3 3
180 21152278 Reactivation of human acetylcholinesterase and butyrylcholinesterase inhibited by leptophos-oxon with different oxime reactivators in vitro. 2010 Aug 3 4
181 21787634 Reactivation of VX-inhibited AChE by novel oximes having two oxygen atoms in the linker. 2010 Jul 2
182 19150463 The possible use of oximes as antidotal therapy in organophosphate-induced brain damage. 2009 Mar 3
183 19428926 Comparison of the oxime-induced reactivation of rhesus monkey, swine and guinea pig erythrocyte acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity. 2009 Apr 28 2
184 19428953 Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: a kinetic analysis. 2009 May 17 1
185 19429253 Interaction of pentylsarin analogues with human acetylcholinesterase: a kinetic study. 2009 Jun 1 3
186 19449818 Nucleophilic reactivation of sarin-inhibited acetylcholinesterase: a molecular modeling study. 2009 Jun 18 3
187 19465093 Effects of oximes on mitochondrial oxidase activity. 2009 Sep 10 2
188 19526299 Efficacy of eight experimental bispyridinium oximes against paraoxon-induced mortality: comparison with the conventional oximes pralidoxime and obidoxime. 2009 Jul 2
189 19586353 In vitro oxime-assisted reactivation of paraoxon-inhibited human acetylcholinesterase and butyrylcholinesterase. 2009 Jul 2
190 19642642 Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime. 2009 Dec 10 1
191 19737786 Poisoning with the S-Alkyl organophosphorus insecticides profenofos and prothiofos. 2009 Nov 1
192 19761810 Reactivation of tabun-hAChE investigated by structurally analogous oximes and mutagenesis. 2009 Nov 30 2
193 20032868 Novel bisquaternary oximes--reactivation of acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon. 2009 Dec 1 1
194 17977518 Comparison of the oxime-induced reactivation of erythrocyte and muscle acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity. 2008 Feb 1 2
195 18281016 Effects of oximes on rate of decarbamylation of human red blood cell AChE measured with two different methods. 2008 Apr 1 4
196 18304715 Identical kinetics of human erythrocyte and muscle acetylcholinesterase with respect to carbamate pre-treatment, residual activity upon soman challenge and spontaneous reactivation after withdrawal of the inhibitors. 2008 Apr 18 2
197 18344198 In vitro oxime protection of human red blood cell acetylcholinesterase inhibited by diisopropyl-fluorophosphate. 2008 May 2
198 18393843 Entry of oximes into the brain: a review. 2008 1
199 18501341 Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning. 2008 Sep 25 5
200 18547553 New bispyridinium oximes: in vitro and in vivo evaluation of their biological efficiency in soman and tabun poisoning. 2008 Sep 25 2