Paraoxon

acetylcholinesterase (Cartwright blood group) ; Homo sapiens







92 Article(s)
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1 33563155 Synthesis, Molecular Docking, BSA, and In Vitro Reactivation Study of Imidazopyridine Oximes Against Paraoxon Inhibited Acetylcholinesterase. 2022 1
2 34506764 α-tocopherol, a slow-binding inhibitor of acetylcholinesterase. 2021 Oct 1 1
3 31675511 6-Methyluracil derivatives as peripheral site ligand-hydroxamic acid conjugates: Reactivation for paraoxon-inhibited acetylcholinesterase. 2020 Jan 1 4
4 32397331 Patterned Superhydrophobic SERS Substrates for Sample Pre-Concentration and Demonstration of Its Utility through Monitoring of Inhibitory Effects of Paraoxon and Carbaryl on AChE. 2020 May 8 2
5 32454005 Synthesis and in vitro evaluation of novel non-oximes for the reactivation of nerve agent inhibited human acetylcholinesterase. 2020 Aug 1 1
6 32583098 Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers. 2020 Sep 1
7 31170561 Rational in silico design of aptamers for organophosphates based on the example of paraoxon. 2019 Jun 3
8 31276662 Reactivation potency of two novel oximes (K456 and K733) against paraoxon-inhibited acetyl and butyrylcholinesterase: In silico and in vitro models. 2019 Sep 1 2
9 31360962 Molecular recognition of organophosphorus compounds in water and inhibition of their toxicity to acetylcholinesterase. 2019 Aug 13 1
10 28722512 In silico and in vitro evaluation of two novel oximes (K378 and K727) in comparison to K-27 and pralidoxime against paraoxon-ethyl intoxication. 2018 Jan 1
11 29451128 Signal-amplifying nanoparticle/hydrogel hybrid microarray biosensor for metal-enhanced fluorescence detection of organophosphorus compounds. 2018 Mar 16 1
12 29652477 Targeted Nanoparticles for Selective Marking of Neuromuscular Junctions and ex Vivo Monitoring of Endogenous Acetylcholine Hydrolysis. 2018 May 2 1
13 29735900 Synthesis, Biological Evaluation, and Docking Studies of Novel Bisquaternary Aldoxime Reactivators on Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon. 2018 May 7 1
14 29773682 Water structure changes in oxime-mediated reactivation process of phosphorylated human acetylcholinesterase. 2018 Jun 29 2
15 30096649 Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase. 2018 Sep 5 2
16 30205495 Novel Group of AChE Reactivators-Synthesis, In Vitro Reactivation and Molecular Docking Study. 2018 Sep 7 1
17 30312685 Interactions between acetylcholinesterase, toxic organophosphorus compounds and a short series of structurally related non-oxime reactivators: Analysis of reactivation and inhibition kinetics in vitro. 2018 Dec 15 1
18 30424582 Molecular Modeling and In Vitro Studies of a Neutral Oxime as a Potential Reactivator for Acetylcholinesterase Inhibited by Paraoxon. 2018 Nov 12 1
19 29201079 Docking Studies, Synthesis, and In-vitro Evaluation of Novel Oximes Based on Nitrones as Reactivators of Inhibited Acetylcholinesterase. 2017 Summer 2
20 26427931 Monooxime Bispyridinium Reactivators Bearing Xylene Linker Synthesis and In Vitro Evaluation on Model of Organophosphate-Inhibited Acetylcholinesterase. 2016 2
21 26751814 Intranasal delivery of obidoxime to the brain prevents mortality and CNS damage from organophosphate poisoning. 2016 Mar 1
22 26965078 Comparison of inhibition kinetics of several organophosphates, including some nerve agent surrogates, using human erythrocyte and rat and mouse brain acetylcholinesterase. 2016 Apr 25 1
23 27191504 Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. 2016 Sep 3
24 27251198 Screen-printed electrode modified with carbon black and chitosan: a novel platform for acetylcholinesterase biosensor development. 2016 Oct 1
25 27260432 A sensitive acetylcholinesterase biosensor based on gold nanorods modified electrode for detection of organophosphate pesticide. 2016 Aug 15 1
26 27494215 Biological Testing of Organophosphorus-Inactivated Acetylcholinesterase Oxime Reactivators Identified via Virtual Screening. 2016 Sep 19 1
27 27682399 Fluorescence Resonance Energy Transfer-based Biosensor Composed of Nitrogen-doped Carbon Dots and Gold Nanoparticles for the Highly Sensitive Detection of Organophosphorus Pesticides. 2016 1
28 24225492 Thiocholine mediated stabilization of in situ produced CdS quantum dots: application for the detection of acetylcholinesterase activity and inhibitors. 2014 Jan 7 1
29 24599312 Tryptoline-3-hydroxypyridinaldoxime conjugates as efficient reactivators of phosphylated human acetyl and butyrylcholinesterases. 2014 Apr 18 1
30 24704618 Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase. 2014 May 6 1
31 24832999 Functionalized graphene oxide for the fabrication of paraoxon biosensors. 2014 May 27 1
32 25190468 Assessment of antidotal efficacy of cholinesterase reactivators against paraoxon: In vitro reactivation kinetics and physicochemical properties. 2014 Oct 1 2
33 22975155 Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates. 2013 Mar 25 1
34 23631528 Designed amphiphilic β-sheet peptides as templates for paraoxon adsorption and detection. 2013 Jun 11 2
35 21761139 Effects of acetylcholinesterase inhibitor paraoxon denote the possibility of non-quantal acetylcholine release in myocardium of different vertebrates. 2012 Jan 1
36 22343626 Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases. 2012 Apr 6 1
37 20888407 Fullerene antioxidants decrease organophosphate-induced acetylcholinesterase inhibition in vitro. 2011 Feb 1
38 21215642 Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage-Preparation, in vitro screening and molecular docking. 2011 Jan 15 2
39 21376964 A sensitive enzymatic method for paraoxon detection based on enzyme inhibition and fluorescence quenching. 2011 Apr 15 1
40 21600321 An acetylcholinesterase biosensor for determination of low concentrations of Paraoxon and Dichlorvos. 2011 Dec 15 4
41 21673941 In vitro ability of currently available oximes to reactivate organophosphate pesticide-inhibited human acetylcholinesterase and butyrylcholinesterase. 2011 2
42 21787676 Effects of paraoxon on neuronal and lymphocytic cholinergic systems. 2011 Jan 3
43 21889639 Surface-enhanced Raman scattering detection of cholinesterase inhibitors. 2011 Oct 10 1
44 21930118 Reactivation of organophosphate-inhibited human acetylcholinesterase by isonitrosoacetone (MINA): a kinetic analysis. 2011 Nov 15 1
45 20113735 AChE biosensor based on zinc oxide sol-gel for the detection of pesticides. 2010 Feb 28 1
46 20144593 Synthesis and evaluation of novel analogues of vitamin B6 as reactivators of tabun and paraoxon inhibited acetylcholinesterase. 2010 Sep 6 1
47 20510904 Disposable electrochemical printed gold chips for the analysis of acetylcholinesterase inhibition. 2010 Jun 11 1
48 19492815 Development of a bioactive paper sensor for detection of neurotoxins using piezoelectric inkjet printing of sol-gel-derived bioinks. 2009 Jul 1 2
49 19586353 In vitro oxime-assisted reactivation of paraoxon-inhibited human acetylcholinesterase and butyrylcholinesterase. 2009 Jul 2
50 19640713 New series of monoquaternary pyridinium oximes: Synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase. 2009 Sep 1 1