pyridine

acetylcholinesterase (Cartwright blood group) ; Homo sapiens







27 Article(s)
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1 35221376 Synthesis, kinetic evaluation and molecular docking studies of donepezil-based acetylcholinesterase inhibitors. 2022 Jan 5 1
2 33638151 Ligand design for human acetylcholinesterase and nicotinic acetylcholine receptors, extending beyond the conventional and canonical. 2021 Sep 2
3 33991570 In-vitro evaluation of antioxidant and anticholinesterase activities of novel pyridine, quinoxaline and s-triazine derivatives. 2021 Aug 1
4 30978400 Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase. 2019 Jun 1 1
5 31139552 Experimental and Theoretical Approaches in the Study of Phenanthroline-Tetrahydroquinolines for Alzheimer's Disease. 2019 May 2
6 31585263 Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments. 2019 Dec 1
7 29131470 Synthesis of some novel pyridine compounds containing bis-1,2,4-triazole/thiosemicarbazide moiety and investigation of their antioxidant properties, carbonic anhydrase, and acetylcholinesterase enzymes inhibition profiles. 2018 Jan 1
8 29735900 Synthesis, Biological Evaluation, and Docking Studies of Novel Bisquaternary Aldoxime Reactivators on Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon. 2018 May 7 1
9 29031067 New pyridine derivatives as inhibitors of acetylcholinesterase and amyloid aggregation. 2017 Dec 1 1
10 27581632 Synthesis, Biological Evaluation and Molecular Docking Study of Hydrazone-Containing Pyridinium Salts as Cholinesterase Inhibitors. 2016 2
11 25218671 Quantum chemical and steered molecular dynamics studies for one pot solution to reactivate aged acetylcholinesterase with alkylator oxime. 2014 Nov 5 1
12 25453812 New efficient imidazolium aldoxime reactivators for nerve agent-inhibited acetylcholinesterase. 2014 Dec 15 1
13 23445881 5,6-Dimethoxybenzofuran-3-one derivatives: a novel series of dual Acetylcholinesterase/Butyrylcholinesterase inhibitors bearing benzyl pyridinium moiety. 2013 Feb 27 1
14 23073222 The 3D-QSAR study of 110 diverse, dual binding, acetylcholinesterase inhibitors based on alignment independent descriptors (GRIND-2). The effects of conformation on predictive power and interpretability of the models. 2012 Sep 2
15 23148598 Phenyltetrahydroisoquinoline-pyridinaldoxime conjugates as efficient uncharged reactivators for the dephosphylation of inhibited human acetylcholinesterase. 2012 Dec 13 2
16 20546883 Passive diffusion of acetylcholinesterase oxime reactivators through the blood-brain barrier: influence of molecular structure. 2010 Sep 1
17 21787634 Reactivation of VX-inhibited AChE by novel oximes having two oxygen atoms in the linker. 2010 Jul 1
18 18617161 Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro. 2008 Sep 25 1
19 17960099 Targeted synthesis of 1-(4-hydroxyiminomethylpyridinium)-3-pyridiniumpropane dibromide--a new nerve agent reactivator. 2007 Aug 20 2
20 16198581 Search for dual function inhibitors for Alzheimer's disease: synthesis and biological activity of acetylcholinesterase inhibitors of pyridinium-type and their Abeta fibril formation inhibition capacity. 2006 Jan 15 3
21 16828550 Bis-pyridiumaldoxime reactivators connected with CH2O(CH2)n OCH2 linkers between pyridinium rings and their reactivity against VX. 2006 Sep 15 1
22 11831902 Pyridophens: binary pyridostigmine-aprophen prodrugs with differential inhibition of acetylcholinesterase, butyrylcholinesterase, and muscarinic receptors. 2002 Feb 14 1
23 10488245 Inhibition of acetylcholinesterase by three new pyridinium compounds and their effect on phosphonylation of the enzyme. 1999 1
24 8343989 Interaction of imidazolium and pyridinium dioximes with human erythrocyte acetylcholinesterase. 1993 Jun 2
25 435080 1,3-Bispyridinium-dimethylether mono- and dioximes: synthesis, reactivating potency and therapeutic effect in experimental poisoning by organophosphorus compounds. 1979 Feb 23 1
26 674296 Protective effects of a series of new pyridinium derivatives against inhibition of acetylcholinesterase by fluostigmine. 1978 Feb-Mar 3
27 1036947 [Reactivation of phosphorylated acetylcholinesterase (AChE): quaternary salts of vinylogous pyridinaldoxims (author's transl)]. 1976 2