Physostigmine

acetylcholinesterase (Cartwright blood group) ; Homo sapiens







84 Article(s)
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1 33478277 Discovery of new acetylcholinesterase inhibitors for Alzheimer's disease: virtual screening and in vitro characterisation. 2021 Dec 1
2 33357230 Indirect cholinergic activation slows down pancreatic cancer growth and tumor-associated inflammation. 2020 Dec 24 1
3 31398669 Continuous infusion of physostigmine in patients with perioperative septic shock: A pharmacokinetic/pharmacodynamic study with population pharmacokinetic modeling. 2019 Oct 1
4 31517530 Computational insight into the anticholinesterase activities and electronic properties of physostigmine analogs. 2019 Aug 1
5 28373858 Enhanced Cholinergic Activity Improves Cerebral Blood Flow during Orthostatic Stress. 2017 1
6 26902639 Human serum albumin reduces the potency of acetylcholinesterase inhibitor based drugs for Alzheimer's disease. 2016 Apr 5 2
7 25446352 The role of ventral midline thalamus in cholinergic-based recovery in the amnestic rat. 2015 Jan 29 1
8 26200465 A Randomized, Prospective, Double-Blinded Study of Physostigmine to Prevent Sedation-Induced Ventilatory Arrhythmias. 2015 Sep 1
9 23229229 In vitro inhibitory profile of NDGA against AChE and its in silico structural modifications based on ADME profile. 2013 Mar 2
10 23747570 Synaptic muscarinic response types in hippocampal CA1 interneurons depend on different levels of presynaptic activity and different muscarinic receptor subtypes. 2013 Oct 1
11 23975732 Cholinergic enhancement differentially modulates neural response to encoding during face identity and face location working memory tasks. 2013 Sep 1
12 22200647 Ibogaine and the inhibition of acetylcholinesterase. 2012 Feb 15 1
13 22461927 Massive atropine eye drop ingestion treated with high-dose physostigmine to avoid intubation. 2012 Feb 1
14 21402092 Pre- and post-treatment effect of physostigmine on soman-inhibited human erythrocyte and muscle acetylcholinesterase in vitro. 2011 May 15 4
15 21414391 In vitro kinetic interactions of pyridostigmine, physostigmine and soman with erythrocyte and muscle acetylcholinesterase from different species. 2011 Sep 25 1
16 20737911 Acetylcholinesterase inhibitory activity of uleine from Himatanthus lancifolius. 2010 Jul-Aug 1
17 18729824 Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions. 2009 Jan 1 2
18 19416629 M(1) and M(3) muscarinic receptors are involved in the release of urinary bladder-derived relaxant factor. 2009 May 1
19 19843075 Ligand-based 3D-QSAR studies of physostigmine analogues as acetylcholinesterase inhibitors. 2009 Dec 3
20 18281016 Effects of oximes on rate of decarbamylation of human red blood cell AChE measured with two different methods. 2008 Apr 1 1
21 18304715 Identical kinetics of human erythrocyte and muscle acetylcholinesterase with respect to carbamate pre-treatment, residual activity upon soman challenge and spontaneous reactivation after withdrawal of the inhibitors. 2008 Apr 18 6
22 18844288 Pharmacological and biological screening of ascorbigen: protection against glucose-induced endothelial cell toxicity. 2008 Dec 1
23 16971898 Scopolamine induces disruption of latent inhibition which is prevented by antipsychotic drugs and an acetylcholinesterase inhibitor. 2007 May 1
24 17134713 Characterization of reversible and pseudo-irreversible acetylcholinesterase inhibitors by means of an immobilized enzyme reactor. 2007 Mar 9 1
25 17979787 Cerebral acetylcholinesterase imaging: development of the radioprobes. 2007 1
26 16797163 Cognitive effects of adjunctive 24-weeks Rivastigmine treatment to antipsychotics in schizophrenia: a randomized, placebo-controlled, double-blind investigation. 2006 Jul 1
27 15611638 Novel assay utilizing fluorochrome-tagged physostigmine (Ph-F) to in situ detect active acetylcholinesterase (AChE) induced during apoptosis. 2005 Jan 3
28 15803498 Acute effects of physostigmine and galantamine on the binding of [18F]fluoro-A-85380: a PET study in monkeys. 2005 Jun 15 2
29 15892689 Human acetylcholinesterase inhibitors: electronic-topological and neural network approaches to the structure-activity relationships study. 2005 May 2
30 15038335 Treatment of opioid-induced delirium with acetylcholinesterase inhibitors: a case report. 2004 Mar 1
31 15134572 Acetylcholinesterase imaging: its use in therapy evaluation and drug design. 2004 1
32 15351315 An in vitro investigation of the effects of the nerve agent pretreatment pyridostigmine bromide on human peripheral blood T-cell function. 2004 Nov 2
33 12840078 Septal modulation of excitatory transmission in hippocampus. 2003 Oct 1
34 11956509 Cholinergic toxic syndrome by the anticancer drug irinotecan: acetylcholinesterase does not play a major role. 2002 Apr 1
35 11979423 Inhibition of acetylcholinesterase by physostigmine analogs: conformational mobility of cysteine loop due to the steric effect of the alkyl chain. 2002 2
36 11176277 Quantitative measurement of cerebral acetylcholinesterase using. 2001 Feb 1
37 11405996 Physostigmine for Alzheimer's disease. 2001 1
38 11893059 Donepezil hydrochloride: a treatment drug for Alzheimer's disease. 2001 1
39 10637365 Molecular modelling and QSAR of reversible acetylcholines-terase inhibitors. 2000 Mar 1
40 10637367 Donepezil hydrochloride (E2020) and other acetylcholinesterase inhibitors. 2000 Mar 1
41 10718513 Cholinergic enhancement improves performance on working memory by modulating the functional activity in distinct brain regions: a positron emission tomography regional cerebral blood flow study in healthy humans. 2000 Feb 1
42 10976649 Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex. 2000 Sep 1
43 11256231 Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. 2000 Oct 1
44 11139819 Rivastigmine, a brain-region selective acetylcholinesterase inhibitor for treating Alzheimer's disease: review and current status. 1999 Oct 1
45 9568379 Effects of hexamethonium, phenothiazines, propranolol and ephedrine on acetylcholinesterase carbamylation by physostigmine, aldicarb and carbaryl: interaction between the active site and the functionally distinct peripheral sites in acetylcholinesterase. 1998 Jan 12
46 9675107 Kinetics of human erythrocyte acetylcholinesterase inhibition by a novel derivative of physostigmine: phenserine. 1998 Jul 9 1
47 9742217 The 'aromatic patch' of three proximal residues in the human acetylcholinesterase active centre allows for versatile interaction modes with inhibitors. 1998 Oct 1 1
48 9030907 Tacrine inhibits nicotinic secretory and current responses in adrenal chromaffin cells. 1997 Jan 14 1
49 9062656 Abnormalities of acetylcholinesterase in Alzheimer's disease with special reference to effect of acetylcholinesterase inhibitor. 1997 Feb 1
50 9279214 Acetylcholine via muscarinic receptors inhibits histamine release from human isolated bronchi. 1997 Aug 1