| 1 |
35526478 | Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents. | 2022 Aug 5 |
1 |
| 2 |
33538594 | Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Nerve Agents and Subsequent Reactivation by HI-6. | 2021 Mar 15 |
2 |
| 3 |
32454005 | Synthesis and in vitro evaluation of novel non-oximes for the reactivation of nerve agent inhibited human acetylcholinesterase. | 2020 Aug 1 |
1 |
| 4 |
30458057 | Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase. | 2019 Mar 15 |
2 |
| 5 |
30978400 | Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase. | 2019 Jun 1 |
2 |
| 6 |
28446076 | Behavior of uncharged oximes compared to HI6 and 2-PAM in the human AChE-tabun conjugate: a molecular modeling approach. | 2018 May |
2 |
| 7 |
29772260 | Oxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations. | 2018 Aug 1 |
1 |
| 8 |
30205495 | Novel Group of AChE Reactivators-Synthesis, In Vitro Reactivation and Molecular Docking Study. | 2018 Sep 7 |
1 |
| 9 |
26368669 | Application of a dynamic in vitro model with real-time determination of acetylcholinesterase activity for the investigation of tabun analogues and oximes. | 2015 Dec 25 |
2 |
| 10 |
23527625 | Reactivation steps by 2-PAM of tabun-inhibited human acetylcholinesterase: reducing the computational cost in hybrid QM/MM methods. | 2014 |
1 |
| 11 |
24443939 | Exploring the physicochemical properties of oxime-reactivation therapeutics for cyclosarin, sarin, tabun, and VX inactivated acetylcholinesterase. | 2014 Jan 21 |
1 |
| 12 |
22975155 | Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates. | 2013 Mar 25 |
1 |
| 13 |
23376121 | Catalytic-site conformational equilibrium in nerve-agent adducts of acetylcholinesterase: possible implications for the HI-6 antidote substrate specificity. | 2013 May 1 |
2 |
| 14 |
22343626 | Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases. | 2012 Apr 6 |
1 |
| 15 |
22808117 | Energetics of Ortho-7 (oxime drug) translocation through the active-site gorge of tabun conjugated acetylcholinesterase. | 2012 |
1 |
| 16 |
23148598 | Phenyltetrahydroisoquinoline-pyridinaldoxime conjugates as efficient uncharged reactivators for the dephosphylation of inhibited human acetylcholinesterase. | 2012 Dec 13 |
1 |
| 17 |
20408548 | Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation. | 2010 May 27 |
1 |
| 18 |
18501341 | Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning. | 2008 Sep 25 |
1 |
| 19 |
17370251 | Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro. | 2007 Nov-Dec |
1 |
| 20 |
17562604 | Structure-activity approach in the reactivation of tabun-phosphorylated human acetylcholinesterase with bispyridinium para-aldoximes. | 2007 Jun |
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| 21 |
17924614 | Design of a potent reactivator of tabun-inhibited acetylcholinesterase--synthesis and evaluation of (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide (K203). | 2007 Nov 1 |
1 |
| 22 |
17194020 | New group of xylene linker-containing acetylcholinesterase reactivators as antidotes against the nerve agent cyclosarin. | 2006 Oct |
2 |
| 23 |
15379785 | Specification of the structure of oximes able to reactivate tabun-inhibited acetylcholinesterase. | 2004 Aug |
1 |
| 24 |
5576158 | Diisopropylphosphorofluoridate and Tabun: enzymatic hydrolysis and nerve function. | 1971 Jun 18 |
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