Sarin

acetylcholinesterase (Cartwright blood group) ; Homo sapiens







14 Article(s)
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1 35164361 Discovery of Novel Non-Oxime Reactivators Showing In Vivo Antidotal Efficiency for Sarin Poisoned Mice. 2022 Feb 7 1
2 35526478 Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents. 2022 Aug 5 1
3 33538594 Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Nerve Agents and Subsequent Reactivation by HI-6. 2021 Mar 15 1
4 32388435 Design, synthesis and evaluation of novel nonquaternary and 3 non-oxime reactivators for acetylcholinesterase inhibited by organophosphates. 2020 Jul 1
5 32454005 Synthesis and in vitro evaluation of novel non-oximes for the reactivation of nerve agent inhibited human acetylcholinesterase. 2020 Aug 1 1
6 32583098 Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers. 2020 Sep 1
7 27705071 Sarin (GB, O-isopropyl methylphosphonofluoridate) neurotoxicity: critical review. 2016 Nov 4
8 22975155 Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates. 2013 Mar 25 1
9 22768972 Acetylcholinesterase inhibitors: a patent review (2008 - present). 2012 Aug 1
10 19536291 Structure of HI-6*sarin-acetylcholinesterase determined by X-ray crystallography and molecular dynamics simulation: reactivator mechanism and design. 2009 Jun 18 2
11 17096183 New safe method for preparation of sarin-exposed human erythrocytes acetylcholinesterase using non-toxic and stable sarin analogue isopropyl p-nitrophenyl methylphosphonate and its application to evaluation of nerve agent antidotes. 2006 Dec 2
12 15095579 [In vitro reactivation of acetylcholinesterase inhibition by O-isopropylmethylfluorophosphonate using the bisquarternary oxime, HS-6]. 2004 Mar 1
13 3699334 Kinetic studies and structure-activity relationships of bispyridinium oximes as reactivators of acetylcholinesterase inhibited by organophosphorus compounds. 1986 Apr 1
14 5507658 Dephosphorylation in vivo of brain acetylcholinesterase inhibited by isopropyl methylphosphonofluoridate (Sarin). 1970 Feb 1