Adenosine

5'-nucleotidase ecto ; Homo sapiens







542 Article(s)
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101 32129745 [A new generation of immunotherapies targeting the CD39/CD73/adenosine pathway to promote the anti-tumor immune response]. 2020 Feb 1
102 32141895 Erythrocyte adaptive metabolic reprogramming under physiological and pathological hypoxia. 2020 May 2
103 32156055 Opposing Effects of Adenosine and Inosine in Human Subcutaneous Fibroblasts May Be Regulated by Third Party ADA Cell Providers. 2020 Mar 7 2
104 32160899 Frequency of circulating CD8+CD73+T cells is associated with survival in nivolumab-treated melanoma patients. 2020 Mar 11 1
105 32165041 Structural investigation on thiazolo[5,4-d]pyrimidines to obtain dual-acting blockers of CD73 and adenosine A2A receptor as potential antitumor agents. 2020 May 1 1
106 32205841 CD73 promotes tumor metastasis by modulating RICS/RhoA signaling and EMT in gastric cancer. 2020 Mar 23 3
107 32212732 Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73. 2020 Apr 23 1
108 32225110 Radiolabeled Human Monoclonal Antibody 067-213 has the Potential for Noninvasive Quantification of CD73 Expression. 2020 Mar 26 2
109 32259773 Adenosine augments the production of IL-10 in cervical cancer cells through interaction with the A2B adenosine receptor, resulting in protection against the activity of cytotoxic T cells. 2020 Apr 4 1
110 32266820 The expression of CD73 on pathological B-cells is associated with shorter overall survival of patients with CLL. 2020 Jul 1
111 32280302 The yin and yang functions of extracellular ATP and adenosine in tumor immunity. 2020 1
112 32289379 The TGF-β profibrotic cascade targets ecto-5'-nucleotidase gene in proximal tubule epithelial cells and is a traceable marker of progressive diabetic kidney disease. 2020 Jul 1 3
113 32312837 Myeloid Cell-Derived TGFβ Signaling Regulates ECM Deposition in Mammary Carcinoma via Adenosine-Dependent Mechanisms. 2020 Jun 15 1
114 32313990 Apoptotic and anti-proliferative effect of guanosine and guanosine derivatives in HuT-78 T lymphoma cells. 2020 Jul 1
115 32344922 Adenosinergic System Involvement in Ischemic Stroke Patients' Lymphocytes. 2020 Apr 25 2
116 32345959 Breast cancer-derived exosomes transmit lncRNA SNHG16 to induce CD73+γδ1 Treg cells. 2020 Apr 29 1
117 32351498 CD73's Potential as an Immunotherapy Target in Gastrointestinal Cancers. 2020 1
118 32363113 Prognostic value of CD73 expression in resected colorectal cancer liver metastasis. 2020 2
119 32409420 Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade. 2020 May 3
120 32417936 CD73 as a target to improve temozolomide chemotherapy effect in glioblastoma preclinical model. 2020 Jun 1
121 32489531 CD73+ extracellular vesicles inhibit angiogenesis through adenosine A2B receptor signalling. 2020 1
122 32548862 CD8+ CD73+ T cells in the tumor microenvironment of head and neck cancer patients are linked to diminished T cell infiltration and activation in tumor tissue. 2020 Dec 1
123 32585229 The therapeutic potential of targeting CD73 and CD73-derived adenosine in melanoma. 2020 Sep 8
124 32614585 Discovery of AB680: A Potent and Selective Inhibitor of CD73. 2020 Oct 22 4
125 32641760 Conversion of extracellular ATP into adenosine: a master switch in renal health and disease. 2020 Sep 1
126 32643277 CD73 acts as a prognostic biomarker and promotes progression and immune escape in pancreatic cancer. 2020 Aug 1
127 32721947 Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration. 2020 Sep 3 1
128 32739778 Preventing ATP Degradation by ASO-Mediated Knockdown of CD39 and CD73 Results in A2aR-Independent Rescue of T Cell Proliferation. 2020 Sep 4 4
129 32755765 Adenosine and adenosine receptors in colorectal cancer. 2020 Oct 1
130 32760402 Targeting Immunometabolism Mediated by CD73 Pathway in EGFR-Mutated Non-small Cell Lung Cancer: A New Hope for Overcoming Immune Resistance. 2020 1
131 32786396 Targeting Metabolism of Extracellular Nucleotides via Inhibition of Ectonucleotidases CD73 and CD39. 2020 Nov 25 1
132 32824670 Decreased Equilibrative Nucleoside Transporter 1 (ENT1) Activity Contributes to the High Extracellular Adenosine Levels in Mesenchymal Glioblastoma Stem-Like Cells. 2020 Aug 18 1
133 32847938 An IL6-Adenosine Positive Feedback Loop between CD73+ γδTregs and CAFs Promotes Tumor Progression in Human Breast Cancer. 2020 Oct 4
134 32865411 Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine Production. 2020 Sep 24 9
135 32943546 Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function. 2020 Nov 1
136 32985862 NMR-Based Assay for the Ex Vivo Determination of Soluble CD73 Activity in Serum. 2020 Nov 3 2
137 33013365 Nucleotide Analog ARL67156 as a Lead Structure for the Development of CD39 and Dual CD39/CD73 Ectonucleotidase Inhibitors. 2020 2
138 33045579 Implications of CD39 in immune-related diseases. 2020 Dec 2
139 33072107 Decreased Frequency of Intestinal CD39+ γδ+ T Cells With Tissue-Resident Memory Phenotype in Inflammatory Bowel Disease. 2020 2
140 33087577 Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling. 2020 Nov 3 1
141 33122192 A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms. 2020 Dec 25 1
142 33123122 CXCR4 Inhibition Counteracts Immunosuppressive Properties of Metastatic NSCLC Stem Cells. 2020 1
143 33146056 Fully human anti-CD39 antibody potently inhibits ATPase activity in cancer cells via uncompetitive allosteric mechanism. 2020 Jan-Dec 2
144 33177176 Prognostic significance and immune correlates of CD73 expression in renal cell carcinoma. 2020 Nov 2
145 33187081 Enzymatic Activity of CD73 Modulates Invasion of Gliomas via Epithelial-Mesenchymal Transition-Like Reprogramming. 2020 Nov 11 2
146 33198064 Methylation of the NT5E Gene Is Associated with Poor Prognostic Factors in Breast Cancer. 2020 Nov 12 2
147 33214837 Fluorescent Probes for Ecto-5'-nucleotidase (CD73). 2020 Nov 12 2
148 33322215 Role of Hypoxia and the Adenosine System in Immune Evasion and Prognosis of Patients with Brain Metastases of Melanoma: A Multiplex Whole Slide Immunofluorescence Study. 2020 Dec 13 1
149 33325366 [Progress on role of extracellular ATP and its metabolite adenosine in immunoregulation: Review]. 2020 Dec 2
150 33335662 Synthesis, Characterization, and In Silico Studies of Novel Spirooxindole Derivatives as Ecto-5'-Nucleotidase Inhibitors. 2020 Dec 10 1