8-Hydroxy-2-(di-n-propylamino)tetralin

5-hydroxytryptamine receptor 1A ; Homo sapiens







293 Article(s)
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1 32315693 Administration of low doses of the 5-HT1A receptor agonist 8-OH-DPAT attenuates the discriminative signal of amphetamine in the conditioned taste aversion procedure. 2020 Jun 4
2 32396921 Medial PFC AMPA receptor and BDNF signaling are required for the rapid and sustained antidepressant-like effects of 5-HT1A receptor stimulation. 2020 Sep 1
3 33384591 Cannabidiol Acts at 5-HT1A Receptors in the Human Brain: Relevance for Treating Temporal Lobe Epilepsy. 2020 1
4 30858018 Cannabinoid CB1 receptors mediate the anxiolytic effects induced by systemic alprazolam and intra-periaqueductal gray 5-HT1A receptor activation. 2019 Jun 11 1
5 31289857 Biphasic effects of 5-HT1A agonism on impulsive responding are dissociable from effects on anxiety in the variable consecutive number task. 2019 Nov 3
6 29057454 Cannabidiolic acid methyl ester, a stable synthetic analogue of cannabidiolic acid, can produce 5-HT1A receptor-mediated suppression of nausea and anxiety in rats. 2018 Jan 1
7 29339052 Neurophysiological effects in cortico-basal ganglia-thalamic circuits of antidyskinetic treatment with 5-HT1A receptor biased agonists. 2018 Apr 1
8 29660440 The long-term effect of maternal dietary protein restriction on 5-HT1A receptor function and behavioral responses to stress in adulthood. 2018 Sep 3 1
9 29730825 18F-F13640 preclinical evaluation in rodent, cat and primate as a 5-HT1A receptor agonist for PET neuroimaging. 2018 Jul 2
10 30347827 Oncotoxic Properties of Serotonin Transporter Inhibitors and 5-HT1A Receptor Ligands. 2018 Oct 20 2
11 28347824 Participation of dorsal periaqueductal gray 5-HT1A receptors in the panicolytic-like effect of the κ-opioid receptor antagonist Nor-BNI. 2017 Jun 1 1
12 26612522 5-hydroxytryptamine1A (5-HT1A) receptor agonists: A decade of empirical evidence supports their use as an efficacious therapeutic strategy for brain trauma. 2016 Jun 1 2
13 26749090 5-Hydroxytryptamine 1A receptors in the dorsomedial hypothalamus connected to dorsal raphe nucleus inputs modulate defensive behaviours and mediate innate fear-induced antinociception. 2016 Mar 1
14 26856853 Repeated administration of the 5-HT₁B/₁A agonist, RU 24969, facilitates the acquisition of MDMA self-administration: role of 5-HT₁A and 5-HT₁B receptor mechanisms. 2016 Apr 1
15 26876117 Dopamine D2 and serotonin 5-HT1A receptor interaction in the context of the effects of antipsychotics - in vitro studies. 2016 May 1
16 25288485 Expression of the 5-HT1A serotonin receptor in the hippocampus is required for social stress resilience and the antidepressant-like effects induced by the nicotinic partial agonist cytisine. 2015 Mar 1
17 25363799 The phytocannabinoid, Δ⁹-tetrahydrocannabivarin, can act through 5-HT₁A receptors to produce antipsychotic effects. 2015 Mar 1
18 25687330 Escitalopram Ameliorates Forskolin-Induced Tau Hyperphosphorylation in HEK239/tau441 Cells. 2015 Jun 1
19 26080602 [On the Functional Cross-Talk between Brain 5-HT1A and 5-HT2A Receptors]. 2015 Mar-Apr 2
20 24385311 (11)C-CUMI-101, a PET radioligand, behaves as a serotonin 1A receptor antagonist and also binds to α(1) adrenoceptors in brain. 2014 Jan 1
21 24429224 Clozapine effects on adenylyl cyclase activity and serotonin type 1A receptors in human brain post-mortem. 2014 Apr 1
22 24830553 The Drosophila Kctd-family homologue Kctd12-like modulates male aggression and mating behaviour. 2014 Aug 1
23 25304920 Alterations of 5-HT1A receptor-induced G-protein functional activation and relationship to memory deficits in patients with pharmacoresistant temporal lobe epilepsy. 2014 Dec 1
24 23299041 Serotonin 5-HT1A receptor in infancy-onset aggression: comparison with genetically defined aggression in adult rats. 2013 Apr 15 1
25 23354536 Effects of repeated exposure to MDMA on 5HT1a autoreceptor function: behavioral and neurochemical responses to 8-OHDPAT. 2013 May 1
26 24157794 Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2. 2013 Nov 15 2
27 22465320 Elucidating the role of 5-HT(1A) and 5-HT(7) receptors on 8-OH-DPAT-induced behavioral recovery after experimental traumatic brain injury. 2012 May 2 4
28 22735975 The role of central 5-HT(2C) and NMDA receptors on LPS-induced feeding behavior in chickens. 2012 Sep 1
29 22940695 Effect of chronic l-DOPA treatment on 5-HT(1A) receptors in parkinsonian monkey brain. 2012 Dec 1
30 20656461 Mapping of CBV changes in 5-HT(1A) terminal fields by functional MRI in the mouse brain. 2011 Apr 1
31 21899601 Computational modelling of 5-HT receptor-mediated reorganization of the brainstem respiratory network. 2011 Oct 2
32 19913081 Partial agonistic effect of yokukansan on human recombinant serotonin 1A receptors expressed in the membranes of Chinese hamster ovary cells. 2010 Feb 3 1
33 20223238 Role of 5-HT(1A) receptors in fluoxetine-induced lordosis inhibition. 2010 Jul 2
34 20450907 Actions of the prototypical 5-HT1A receptor agonist 8-OH-DPAT at human alpha2-adrenoceptors: (+)8-OH-DPAT, but not (-)8-OH-DPAT is an alpha2B subtype preferential agonist. 2010 Aug 25 5
35 20488186 The serotonin subtype 1A receptor regulates cortisol secretion in the Gulf toadfish, Opsanus beta. 2010 Sep 15 3
36 20520769 HDAC6 regulates mitochondrial transport in hippocampal neurons. 2010 May 26 1
37 20709144 5-HT(1A)-like receptor activation inhibits abstinence-induced methamphetamine withdrawal in planarians. 2010 Oct 29 1
38 20802053 Repinotan, a selective 5-HT1A-R-agonist, antagonizes morphine-induced ventilatory depression in anesthetized rats. 2010 Oct 1
39 19075042 Characterization of serotonin receptors in pregnant human myometrium. 2009 Mar 1
40 19447286 Memory time-course: mRNA 5-HT1A and 5-HT7 receptors. 2009 Aug 24 2
41 17675218 The platelet of the patients with ischemic cardiopathy and cardiac valve disease showed a reduction of 8OH-DPAT binding sites. 2008 1
42 18094064 Activation of 5-HT1A receptors in medullary raphé disrupts sleep and decreases shivering during cooling in the conscious piglet. 2008 Mar 3
43 18269931 Neuroprotective effects of serotonin 5-HT 1A receptor activation against ischemic cell damage in gerbil hippocampus: Involvement of NMDA receptor NR1 subunit and BDNF. 2008 Mar 14 1
44 18289523 Differential regulation of serotonin-1A receptor-stimulated [35S]GTP gamma S binding in the dorsal raphe nucleus by citalopram and escitalopram. 2008 Mar 31 2
45 18410179 Investigating the motivational mechanism of altered saline consumption following 5-HT(1A) manipulation. 2008 Apr 2
46 18455431 Modulation of neuronal excitability by serotonin-NMDA interactions in prefrontal cortex. 2008 Jun 1
47 18469535 Behavioral characterization of serotonergic activation in the flatworm Planaria. 2008 May 1
48 18513131 The role of 5-HT1A receptors in the behavioral responses associated with innate fear. 2008 Jun 1
49 18622186 Behavior selectively elicited by novel stimuli: modulation by the 5-HT1A agonist 8-OHDPAT and antagonist WAY-100635. 2008 Jul 1
50 18667366 Role of 5-HT(1A) receptors in the lower brainstem on the cardiovascular response to dorsomedial hypothalamus activation. 2008 Nov 3 3