| 1 |
34769439 | IL-4 and IL-13 Promote Proliferation of Mammary Epithelial Cells through STAT6 and IRS-1. | 2021 Nov 5 |
3 |
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27330190 | The adaptor protein insulin receptor substrate 2 inhibits alternative macrophage activation and allergic lung inflammation. | 2016 Jun 21 |
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25151041 | Novel HIV IL-4R antagonist vaccine strategy can induce both high avidity CD8 T and B cell immunity with greater protective efficacy. | 2014 Sep 29 |
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| 4 |
22761864 | IL-4 engagement of the type I IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro. | 2012 |
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| 5 |
22798672 | Tyrosine phosphorylation of c-Maf enhances the expression of IL-4 gene. | 2012 Aug 15 |
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| 6 |
20371618 | CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic mice. | 2010 Aug |
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19592641 | An atopy-associated polymorphism in the ectodomain of the IL-4R(alpha) chain (V50) regulates the persistence of STAT6 phosphorylation. | 2009 Aug 1 |
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| 8 |
19799897 | Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: regulation of the type-II IL-4 receptor chains IL-4Ralpha and IL-13Ralpha1. | 2009 Dec 10 |
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| 9 |
17513737 | Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3. | 2007 Jun 1 |
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| 10 |
17827176 | Dok-1 is a positive regulator of IL-4 signalling and IgE response. | 2007 Aug |
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| 11 |
15128777 | IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules. | 2004 May 15 |
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| 12 |
15526032 | Crosstalk between PKCzeta and the IL4/Stat6 pathway during T-cell-mediated hepatitis. | 2004 Nov 24 |
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| 13 |
12426308 | Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling. | 2003 Jan 31 |
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| 14 |
12637316 | IL-4 synergistically enhances both IL-2- and IL-12-induced IFN-gamma expression in murine NK cells. | 2003 Jul 1 |
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11788580 | Specificity of interleukin-2 receptor gamma chain superfamily cytokines is mediated by insulin receptor substrate-dependent pathway. | 2002 Mar 8 |
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| 16 |
11815609 | Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain. | 2002 Apr 5 |
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| 17 |
12370375 | Role of STAT6 and mast cells in IL-4- and IL-13-induced alterations in murine intestinal epithelial cell function. | 2002 Oct 15 |
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| 18 |
12429573 | Inhibition of cytokine-induced JAK-STAT signalling pathways by an endonuclease inhibitor aurintricarboxylic acid. | 2002 Dec |
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| 19 |
11305324 | Costimulation of resting B lymphocytes alters the IL-4-activated IRS2 signaling pathway in a STAT6 independent manner: implications for cell survival and proliferation. | 2001 Mar |
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| 20 |
10731717 | Suppression of prostaglandin E(2)-mediated c-fos mRNA induction by interleukin-4 in murine macrophages. | 2000 Mar |
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| 21 |
11164892 | IL-4 induces serine phosphorylation of the STAT6 transactivation domain in B lymphocytes. | 2000 Aug |
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| 22 |
9916733 | IgE hyperproduction through enhanced tyrosine phosphorylation of Janus kinase 3 in NC/Nga mice, a model for human atopic dermatitis. | 1999 Jan 15 |
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| 23 |
10202031 | IL-3 and IL-4 activate cyclic nucleotide phosphodiesterases 3 (PDE3) and 4 (PDE4) by different mechanisms in FDCP2 myeloid cells. | 1999 Apr 15 |
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| 24 |
10207105 | Insulin-like growth factor I synergizes with interleukin 4 for hematopoietic cell proliferation independent of insulin receptor substrate expression. | 1999 May |
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| 25 |
10421786 | Activation of STAT5 by IL-4 relies on Janus kinase function but not on receptor tyrosine phosphorylation, and can contribute to both cell proliferation and gene regulation. | 1999 Aug |
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| 26 |
9670964 | Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis. | 1998 Jul 15 |
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| 27 |
8995447 | Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells. | 1997 Jan 10 |
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| 28 |
8999817 | A murine interleukin-4 antagonistic mutant protein completely inhibits interleukin-4-induced cell proliferation, differentiation, and signal transduction. | 1997 Jan 17 |
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| 29 |
9013772 | The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action. | 1997 Feb |
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| 30 |
9045682 | Jak1 expression is required for mediating interleukin-4-induced tyrosine phosphorylation of insulin receptor substrate and Stat6 signaling molecules. | 1997 Mar 7 |
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| 31 |
8602263 | Essential role of Stat6 in IL-4 signalling. | 1996 Apr 18 |
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| 32 |
8703030 | Stat6 and Jak1 are common elements in platelet-derived growth factor and interleukin-4 signal transduction pathways in NIH 3T3 fibroblasts. | 1996 Sep 6 |
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| 33 |
8916957 | Interleukin-4 induces association of the c-fes proto-oncogene product with phosphatidylinositol-3 kinase. | 1996 Nov 15 |
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| 34 |
8954948 | Interleukin-4 activates two distinct pathways of phosphatidylinositol-3 kinase in the same cells. | 1996 Dec 13 |
2 |
| 35 |
7492780 | The insulin receptor substrate-1-related 4PS substrate but not the interleukin-2R gamma chain is involved in interleukin-13-mediated signal transduction. | 1995 Dec 1 |
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| 36 |
7544011 | Interleukin 4 signals through two related pathways. | 1995 Aug 15 |
4 |
| 37 |
7544789 | Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases. | 1995 Sep 1 |
2 |
| 38 |
7544888 | A novel IL-4 responsive element of the E alpha MHC class II promoter that binds to an inducible factor. | 1995 Aug 11 |
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| 39 |
7744881 | Interleukin-13 signal transduction in lymphohemopoietic cells. Similarities and differences in signal transduction with interleukin-4 and insulin. | 1995 May 19 |
4 |
| 40 |
7961833 | Insulin receptor substrate-1 mediates phosphatidylinositol 3'-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation. | 1994 Nov 18 |
2 |
| 41 |
8124718 | An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth. | 1994 Mar 11 |
3 |
| 42 |
7683417 | Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells. | 1993 May 1 |
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| 43 |
8390454 | Interleukin-4 (IL-4) induces protein tyrosine phosphorylation of the IL-4 receptor and association of phosphatidylinositol 3-kinase to the IL-4 receptor in a mouse T cell line, HT2. | 1993 Jun 25 |
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| 44 |
1334461 | IL-4 activates a distinct signal transduction cascade from IL-3 in factor-dependent myeloid cells. | 1992 Dec |
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| 45 |
1692720 | Multiple hematopoietic growth factors signal through tyrosine phosphorylation. | 1990 |
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| 46 |
2334739 | Differential effects of interleukin-2 and interleukin-4 on protein tyrosine phosphorylation in factor-dependent murine T cells. | 1990 May 2 |
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