Simvastatin

AKT serine/threonine kinase 1 ; Homo sapiens







70 Article(s)
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51 20614159 Simvastatin overcomes the resistance to serum withdrawal-induced apoptosis of lymphocytes from Alzheimer's disease patients. 2010 Dec 1
52 20671065 High-density lipoprotein induces proliferation and migration of human prostate androgen-independent cancer cells by an ABCA1-dependent mechanism. 2010 Sep 1
53 19001041 Blunted Akt/FOXO signalling and activation of genes controlling atrophy and fuel use in statin myopathy. 2009 Jan 15 1
54 19513607 Simvastatin increases the activity of endothelial nitric oxide synthase via enhancing phosphorylation. 2009 Jun 3
55 19934968 Effect of simvastatin on glioma cell proliferation, migration, and apoptosis. 2009 Dec 4
56 18371146 Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. 2008 Apr 1
57 18489904 Simvastatin inhibits the proliferation of human prostate cancer PC-3 cells via down-regulation of the insulin-like growth factor 1 receptor. 2008 Jul 25 1
58 18612412 The pleiotropic effects of simvastatin on retinal microvascular endothelium has important implications for ischaemic retinopathies. 2008 Jul 9 1
59 18976673 Disparate effects of simvastatin on angiogenesis during hypoxia and inflammation. 2008 Dec 5 1
60 17172275 Phosphatidylinositol 3-kinase/protein kinase Akt negatively regulates plasminogen activator inhibitor type 1 expression in vascular endothelial cells. 2007 Apr 1
61 16825658 Endothelial cell barrier enhancement by ATP is mediated by the small GTPase Rac and cortactin. 2006 Aug 1
62 16968805 Direct demonstration of an antiinflammatory effect of simvastatin in subjects with the metabolic syndrome. 2006 Nov 1
63 15776112 Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts. 2005 Apr 2
64 15843472 Statins prevent oxidized LDL-induced injury of glomerular podocytes by activating the phosphatidylinositol 3-kinase/AKT-signaling pathway. 2005 Jul 1
65 14732356 Simvastatin suppresses LPS-induced Akt phosphorylation in the human monocyte cell line THP-1. 2004 Jan 3
66 14988829 Simvastatin enhances hepatic nitric oxide production and decreases the hepatic vascular tone in patients with cirrhosis. 2004 Mar 1
67 15337692 Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection. 2004 Sep 7 3
68 11863404 Can simvastatin promote tumor growth by inducing angiogenesis similar to VEGF? 2002 Jan 1
69 11956113 Statin prevents tissue factor expression in human endothelial cells: role of Rho/Rho-kinase and Akt pathways. 2002 Apr 16 2
70 12438947 Simvastatin induces activation of the serine-threonine protein kinase AKT and increases survival of isolated human pancreatic islets. 2002 Oct 27 3