ponatinib

AKT serine/threonine kinase 1 ; Homo sapiens







7 Article(s)
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1 35603651 [Ponatinib inhibits the proliferation of SNU-449 human hepatocellular cancer cells and blocks MAPK and PDK1/AKT/mTOR signaling pathways]. 2022 May 3
2 32470534 Cardiotoxicity of the BCR-ABL1 tyrosine kinase inhibitors: Emphasis on ponatinib. 2020 Oct 1 1
3 30959969 Ponatinib Inhibits Proliferation and Induces Apoptosis of Liver Cancer Cells, but Its Efficacy Is Compromised by Its Activation on PDK1/Akt/mTOR Signaling. 2019 Apr 7 1
4 28427224 Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells. 2017 May 9 1
5 28500237 Resistance to RET-Inhibition in RET-Rearranged NSCLC Is Mediated By Reactivation of RAS/MAPK Signaling. 2017 Aug 1
6 27783942 Dual Targeting of PDGFRα and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors. 2016 Oct 25 1
7 22409268 Ponatinib may overcome resistance of FLT3-ITD harbouring additional point mutations, notably the previously refractory F691I mutation. 2012 May 1