gambogic acid

AKT serine/threonine kinase 1 ; Homo sapiens







20 Article(s)
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1 33971977 Gambogic acid protects LPS-induced apoptosis and inflammation in a cell model of neonatal pneumonia through the regulation of TrkA/Akt signaling pathway. 2021 May 11 6
2 31748028 Gambogic Acid Affects Ribosomal Occurrence in Glioma Cells by Downregulating the Phosphoinositide Kinase-3/Protein Kinase B/Mammalian Target of Rapamycin Signaling Pathway. 2020 Jun 1 3
3 32913452 Gambogic acid affects ESCC progression through regulation of PI3K/AKT/mTOR signal pathway. 2020 3
4 31555380 Gambogic acid suppresses colon cancer cell activity in vitro. 2019 Oct 3
5 30186399 Gambogic acid regulates the migration and invasion of colorectal cancer via microRNA-21-mediated activation of phosphatase and tensin homolog. 2018 Sep 1
6 30269846 Gambogic acid induces cell apoptosis through endoplasmic reticulum stress triggered inhibition of Akt signaling pathways in extranodal NK/T-cell lymphoma cells. 2018 Sep 2
7 28901512 Gambogic acid suppresses inflammation in rheumatoid arthritis rats via PI3K/Akt/mTOR signaling pathway. 2017 Nov 2
8 29050671 Gambogic acid improves non-small cell lung cancer progression by inhibition of mTOR signaling pathway. 2017 Nov 1
9 26318432 Gambogic acid enhances the radiosensitivity of human esophageal cancer cells by inducing reactive oxygen species via targeting Akt/mTOR pathway. 2016 Feb 1
10 27284372 Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF-κB pathway. 2016 Jun 1
11 26205493 Gambogic acid inhibits osteoclast formation and ovariectomy-induced osteoporosis by suppressing the JNK, p38 and Akt signalling pathways. 2015 Aug 1 1
12 24810758 ROS-mediated autophagy induced by dysregulation of lipid metabolism plays a protective role in colorectal cancer cells treated with gambogic acid. 2014 1
13 24890366 Gambogic acid suppresses hypoxia-induced hypoxia-inducible factor-1α/vascular endothelial growth factor expression via inhibiting phosphatidylinositol 3-kinase/Akt/mammalian target protein of rapamycin pathway in multiple myeloma cells. 2014 Aug 3
14 23665322 Gambogic acid induces EGFR degradation and Akt/mTORC1 inhibition through AMPK dependent-LRIG1 upregulation in cultured U87 glioma cells. 2013 Jun 7 6
15 22426696 Gambogic acid inhibits TNF-α-induced invasion of human prostate cancer PC3 cells in vitro through PI3K/Akt and NF-κB signaling pathways. 2012 Apr 3
16 22888247 Synergistic effect of a combination of nanoparticulate Fe3O4 and gambogic acid on phosphatidylinositol 3-kinase/Akt/Bad pathway of LOVO cells. 2012 4
17 23194187 Gambogic acid promotes apoptosis and resistance to metastatic potential in MDA-MB-231 human breast carcinoma cells. 2012 Dec 1
18 19433130 Gambogic acid induces G0/G1 arrest and apoptosis involving inhibition of SRC-3 and inactivation of Akt pathway in K562 leukemia cells. 2009 Aug 3 2
19 18226852 Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cells. 2008 Apr 18 3
20 18339865 Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling. 2008 Mar 15 1