OSI 027

AKT serine/threonine kinase 1 ; Homo sapiens







6 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 33222668 OSI-027 Alleviates Oxaliplatin Chemoresistance in Gastric Cancer Cells by Suppressing P-gp Induction. 2021 1
2 35096817 Dual Inhibition of mTORC1/2 Reduces Migration of Cholangiocarcinoma Cells by Regulation of Matrixmetalloproteinases. 2021 1
3 30650200 Targeting mTORC1/2 with OSI-027 inhibits proliferation and migration of keloid keratinocytes. 2019 Mar 1
4 22476852 Targeting of mTORC2 prevents cell migration and promotes apoptosis in breast cancer. 2012 Aug 1
5 23226094 Targeting TORC1/2 enhances sensitivity to EGFR inhibitors in head and neck cancer preclinical models. 2012 Nov 1
6 21673091 Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin. 2011 Aug 2