Celecoxib

AKT serine/threonine kinase 1 ; Homo sapiens







76 Article(s)
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1 35115900 Celecoxib-Induced Modulation of Colon Cancer CD133 Expression Occurs through AKT Inhibition and Is Monitored by 89Zr Immuno-PET. 2022 3
2 35176901 Celecoxib Synergistically Enhances MLN4924-Induced Cytotoxicity and EMT Inhibition Via AKT and ERK Pathways in Human Urothelial Carcinoma. 2022 Jan-Dec 2
3 33489855 Celecoxib induces apoptosis through Akt inhibition in 5-fluorouracil-resistant gastric cancer cells. 2021 Jan 2
4 32208383 Aberrant cell migration contributes to defective airway epithelial repair in childhood wheeze. 2020 Apr 9 1
5 32705218 Potentiation of TRAIL‑induced cell death by nonsteroidal anti‑inflammatory drug in human hepatocellular carcinoma cells through the ER stress‑dependent autophagy pathway. 2020 Sep 1
6 33019464 The molecular mechanisms of celecoxib in tumor development. 2020 Oct 2 1
7 31613929 Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression. 2019 3
8 29541415 Sensitization of multidrug-resistant cancer cells to Hsp90 inhibitors by NSAIDs-induced apoptotic and autophagic cell death. 2018 Feb 16 1
9 29593389 Liposome encapsulation of doxorubicin and celecoxib in combination inhibits progression of human skin cancer cells. 2018 1
10 30326204 The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy. 2018 Dec 1
11 27666139 Celecoxib enhances the inhibitory effect of 5-FU on human squamous cell carcinoma proliferation by ROS production. 2017 Apr 1
12 28053596 Celecoxib enhances anticancer effect of cisplatin and induces anoikis in osteosarcoma via PI3K/Akt pathway. 2017 3
13 28283800 Blocking COX-2 induces apoptosis and inhibits cell proliferation via the Akt/survivin- and Akt/ID3 pathway in low-grade-glioma. 2017 Apr 2
14 28804691 Combination of celecoxib (Celebrex®) and CD19 CAR-redirected CTL immunotherapy for the treatment of B-cell non-Hodgkin's lymphomas. 2017 1
15 29048666 Synergistic antitumor effects of the combined treatment with an HDAC6 inhibitor and a COX-2 inhibitor through activation of PTEN. 2017 Nov 3
16 29216640 Celecoxib Down-Regulates the Hypoxia-Induced Expression of HIF-1α and VEGF Through the PI3K/AKT Pathway in Retinal Pigment Epithelial Cells. 2017 3
17 26899878 Comparative Proteomic Study of Fatty Acid-treated Myoblasts Reveals Role of Cox-2 in Palmitate-induced Insulin Resistance. 2016 Feb 22 1
18 27835884 Combination of COX-2 expression and PIK3CA mutation as prognostic and predictive markers for celecoxib treatment in breast cancer. 2016 Dec 20 1
19 25701378 Celecoxib sensitizes gastric cancer to rapamycin via inhibition of the Cbl-b-regulated PI3K/Akt pathway. 2015 Jul 5
20 25770423 Activating PTEN by COX-2 inhibitors antagonizes radiation-induced AKT activation contributing to radiosensitization. 2015 May 1 2
21 25851346 Synergistic effect between celecoxib and luteolin is dependent on estrogen receptor in human breast cancer cells. 2015 Aug 2
22 25964548 Combining CAL-101 with Celecoxib Enhances Apoptosis of EBV-transformed B-Cells Through MAPK-induced ER Stress. 2015 May 1
23 26225471 The interplay between GRP78 expression and Akt activation in human colon cancer cells under celecoxib treatment. 2015 Oct 2
24 24520227 Synergistic Effect of COX-2 Inhibitor on Paclitaxel-Induced Apoptosis in the Human Ovarian Cancer Cell Line OVCAR-3. 2014 Jan 1
25 24676394 Celecoxib regulates apoptosis and autophagy via the PI3K/Akt signaling pathway in SGC-7901 gastric cancer cells. 2014 Jun 4
26 24855827 Anticancer effects of celecoxib through inhibiton of STAT3 phosphorylation and AKT phosphorylation in nasopharyngeal carcinoma cell lines. 2014 May 2
27 25107843 The PI3K/Akt pathway in colitis associated colon cancer and its chemoprevention with celecoxib, a Cox-2 selective inhibitor. 2014 Jul 1
28 23229294 Synergistic apoptotic effect of celecoxib and luteolin on breast cancer cells. 2013 Feb 1
29 23524145 Enhanced apoptotic effects by downregulating Mcl-1: evidence for the improvement of photodynamic therapy with Celecoxib. 2013 Jun 10 1
30 23564777 Combining celecoxib with sorafenib synergistically inhibits hepatocellular carcinoma cells in vitro. 2013 Apr 1
31 23679684 Effects of celecoxib treatment over the AKT pathway in head and neck squamous cell carcinoma. 2013 Nov 2
32 23833672 Celecoxib inhibits insulin-like growth factor 1 induced growth and invasion in non-small cell lung cancer. 2013 Jun 2
33 22546756 Cyclooxygenase-2 inhibitors induce anoikis in osteosarcoma via PI3K/Akt pathway. 2012 Jul 1
34 21430081 Celecoxib and 2,5-dimethyl-celecoxib prevent cardiac remodeling inhibiting Akt-mediated signal transduction in an inherited dilated cardiomyopathy mouse model. 2011 Jul 1
35 21807123 The acid sphingomyelinase inhibitors block interferon-α-induced serotonin uptake via a COX-2/Akt/ERK/STAT-dependent pathway in T cells. 2011 Nov 1
36 21868755 Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3. 2011 Oct 1 3
37 19954924 Synergistic anticancer effects of combined gamma-tocotrienol and celecoxib treatment are associated with suppression in Akt and NFkappaB signaling. 2010 May 2
38 20083195 Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium. 2010 Apr 15 3
39 20578837 Activated PI3K/Akt/COX-2 pathway induces resistance to radiation in human cervical cancer HeLa cells. 2010 Jun 1
40 20664740 Celecoxib does not attenuate the antiplatelet effects of aspirin and clopidogrel in healthy volunteers. 2010 Jul 1
41 20926014 Combined inhibitory effects of celecoxib and fluvastatin on the growth of human hepatocellular carcinoma xenografts in nude mice. 2010 Jul-Aug 2
42 18506760 Potent cell growth inhibitory effects in hepatitis B virus X protein positive hepatocellular carcinoma cells by the selective cyclooxygenase-2 inhibitor celecoxib. 2009 Jan 1
43 18823436 Anti-gastric cancer effects of celecoxib, a selective COX-2 inhibitor, through inhibition of Akt signaling. 2009 Mar 2
44 19558494 Inhibition of 12-LOX and COX-2 reduces the proliferation of human epidermoid carcinoma cells (A431) by modulating the ERK and PI3K-Akt signalling pathways. 2009 Nov 1
45 19787257 Synergistic effects of lovastatin and celecoxib on caveolin-1 and its down-stream signaling molecules: Implications for colon cancer prevention. 2009 Nov 1
46 21556247 Effects of celecoxib and ly117018 combination on human breast cancer cells in vitro. 2009 Apr 7 2
47 18078766 Celecoxib, a cyclooxygenase-2 inhibitor, induces apoptosis in human osteosarcoma cell line MG-63 via down-regulation of PI3K/Akt. 2008 May 3
48 18083230 Imatinib-resistant K562 cells are more sensitive to celecoxib, a selective COX-2 inhibitor: role of COX-2 and MDR-1. 2008 Jun 2
49 18172786 Selective COX-2 inhibitor celecoxib combined with EGFR-TKI ZD1839 on non-small cell lung cancer cell lines: in vitro toxicity and mechanism study. 2008 1
50 18201156 Celecoxib to prevent restenosis--results from the COREA-TAXUS trial. 2008 Feb 2