fisetin

AKT serine/threonine kinase 1 ; Homo sapiens







22 Article(s)
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1 33086879 Fisetin Inhibits Autophagy in HepG2 Cells via PI3K/Akt/mTOR and AMPK Pathway. 2021 3
2 34695518 Fisetin-induced PTEN expression reverses cellular senescence by inhibiting the mTORC2-Akt Ser473 phosphorylation pathway in vascular smooth muscle cells. 2021 Dec 1
3 34821587 Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer by targeting PI3K/AKT/mTOR signaling. 2021 Nov 25 1
4 32257052 RNA-seq data analysis of stimulated hepatocellular carcinoma cells treated with epigallocatechin gallate and fisetin reveals target genes and action mechanisms. 2020 2
5 30431692 Fisetin induces apoptosis in breast cancer MDA-MB-453 cells through degradation of HER2/neu and via the PI3K/Akt pathway. 2019 Apr 2
6 30468635 Fisetin protects against rotenone-induced neurotoxicity through signaling pathway. 2019 Jan 1 1
7 31540162 Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models. 2019 Sep 15 3
8 29204750 Protective Effects of Fisetin Against 6-OHDA-Induced Apoptosis by Activation of PI3K-Akt Signaling in Human Neuroblastoma SH-SY5Y Cells. 2018 Feb 5
9 29574877 Fisetin mediated apoptotic cell death in parental and Oxaliplatin/irinotecan resistant colorectal cancer cells in vitro and in vivo. 2018 Sep 1
10 30108501 Fisetin Inhibited Growth and Metastasis of Triple-Negative Breast Cancer by Reversing Epithelial-to-Mesenchymal Transition via PTEN/Akt/GSK3β Signal Pathway. 2018 4
11 28204814 Fisetin regulates astrocyte migration and proliferation in vitro. 2017 Apr 2
12 29296070 Fisetin inhibits epidermal growth factor-induced migration of ARPE-19 cells by suppression of AKT activation and Sp1-dependent MMP-9 expression. 2017 3
13 27158416 Promising tumor inhibiting potentials of Fisetin through PI3K/AKT/mTOR pathway. 2016 1
14 27551764 Fisetin inhibits laryngeal carcinoma through regulation of AKT/NF-κB/mTOR and ERK1/2 signaling pathways. 2016 Oct 2
15 27904686 Fisetin, a dietary phytochemical, overcomes Erlotinib-resistance of lung adenocarcinoma cells through inhibition of MAPK and AKT pathways. 2016 2
16 26590114 Fisetin inhibits TNF-α-induced inflammatory action and hydrogen peroxide-induced oxidative damage in human keratinocyte HaCaT cells through PI3K/AKT/Nrf-2-mediated heme oxygenase-1 expression. 2015 Dec 2
17 24675012 Fisetin inhibits human melanoma cell growth through direct binding to p70S6K and mTOR: findings from 3-D melanoma skin equivalents and computational modeling. 2014 Jun 1 2
18 23538677 Fisetin inhibits osteoclastogenesis through prevention of RANKL-induced ROS production by Nrf2-mediated up-regulation of phase II antioxidant enzymes. 2013 1
19 21618507 Dual inhibition of phosphatidylinositol 3-kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin. 2012 Apr 1 3
20 19633975 Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells. 2010 Jan 2
21 20530556 Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells. 2010 Aug 1
22 20637980 Enhancement of p53-mutant human colorectal cancer cells radiosensitivity by flavonoid fisetin. 2010 Aug 1 1