| 1 |
31032735 | Aberrant Rac pathway signalling in glioblastoma. | 2021 Mar |
1 |
| 2 |
31802643 | Expression of OPN3 in lung adenocarcinoma promotes epithelial-mesenchymal transition and tumor metastasis. | 2020 Feb |
1 |
| 3 |
32322580 | Targeting Rac and Cdc42 GEFs in Metastatic Cancer. | 2020 |
1 |
| 4 |
29858187 | Targeting Rac and Cdc42 GTPases in Cancer. | 2018 Jun 15 |
1 |
| 5 |
28600358 | Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock. | 2017 Jul 21 |
1 |
| 6 |
28666462 | Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis. | 2017 Jun 30 |
1 |
| 7 |
28807941 | The Rac GTPase in Cancer: From Old Concepts to New Paradigms. | 2017 Oct 15 |
1 |
| 8 |
27597758 | Tiam-Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion. | 2016 Sep 12 |
1 |
| 9 |
28255536 | Central role of PI3K-SYK interaction in fibrinogen-induced lamellipodia and filopodia formation in platelets. | 2016 Dec |
2 |
| 10 |
24501217 | Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells. | 2014 Apr 3 |
2 |
| 11 |
24598074 | Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task. | 2014 |
2 |
| 12 |
23441967 | The scaffolding protein GRASP/Tamalin directly binds to Dock180 as well as to cytohesins facilitating GTPase crosstalk in epithelial cell migration. | 2013 Feb 26 |
1 |
| 13 |
24563715 | Dock protein family in brain development and neurological disease. | 2013 Nov 1 |
1 |
| 14 |
25033803 | Development of EHop-016: a small molecule inhibitor of Rac. | 2013 |
1 |
| 15 |
22520755 | Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2. | 2012 Apr 20 |
1 |
| 16 |
22647486 | A shortcut from GPCR signaling to Rac-mediated actin cytoskeleton through an ELMO/DOCK complex. | 2012 Jul-Sep |
1 |
| 17 |
23033540 | The rho exchange factors vav2 and vav3 control a lung metastasis-specific transcriptional program in breast cancer cells. | 2012 Oct 2 |
1 |
| 18 |
23050005 | Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration. | 2012 |
1 |
| 19 |
21111731 | p190RhoGAP mediates protective effects of oxidized phospholipids in the models of ventilator-induced lung injury. | 2011 Apr 1 |
1 |
| 20 |
21943825 | Inactivation of Rac1 reduces Trastuzumab resistance in PTEN deficient and insulin-like growth factor I receptor overexpressing human breast cancer SKBR3 cells. | 2011 Dec 26 |
1 |
| 21 |
20018810 | Phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 (P-Rex-1), a guanine nucleotide exchange factor for Rac, mediates angiogenic responses to stromal cell-derived factor-1/chemokine stromal cell derived factor-1 (SDF-1/CXCL-12) linked to Rac activation, endothelial cell migration, and in vitro angiogenesis. | 2010 Mar |
4 |
| 22 |
20634316 | The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling. | 2010 Jul 15 |
1 |
| 23 |
20958313 | ELMO1 signaling in apoptotic germ cell clearance and spermatogenesis. | 2010 Oct |
1 |
| 24 |
19392649 | Coordinated regulation of Ras-, Rac-, and Ca2+-dependent signaling pathways. | 2009 |
1 |
| 25 |
19956392 | The Guanine Nucleotide Exchange Factor SWAP-70 Modulates the Migration and Invasiveness of Human Malignant Glioma Cells. | 2009 Dec |
1 |
| 26 |
18299239 | The PIX-GIT complex: a G protein signaling cassette in control of cell shape. | 2008 Jun |
1 |
| 27 |
17060455 | The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity. | 2007 Jan |
1 |
| 28 |
17297440 | PIKE-A is a proto-oncogene promoting cell growth, transformation and invasion. | 2007 Jul 26 |
1 |
| 29 |
17339487 | The Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanine. | 2007 Mar 15 |
1 |
| 30 |
16301320 | Phosphorylation of P-Rex1 by the cyclic AMP-dependent protein kinase inhibits the phosphatidylinositiol (3,4,5)-trisphosphate and Gbetagamma-mediated regulation of its activity. | 2006 Jan 27 |
1 |
| 31 |
16597700 | In vivo dynamics of Rac-membrane interactions. | 2006 Jun |
1 |
| 32 |
16049005 | ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth. | 2005 Oct 14 |
1 |
| 33 |
16190977 | RhoGDIs revisited: novel roles in Rho regulation. | 2005 Nov |
2 |
| 34 |
14761976 | PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion. | 2004 Apr 16 |
1 |
| 35 |
15121857 | Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2. | 2004 May |
1 |
| 36 |
12471028 | Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam. | 2003 Feb 14 |
1 |
| 37 |
12475976 | The guanine nucleotide exchange factor trio activates the phagocyte NADPH oxidase in the absence of GDP to GTP exchange on Rac. "The emperor's nw clothes". | 2003 Feb 14 |
1 |
| 38 |
12777642 | Protein interaction for an interferon-inducible systemic lupus associated gene, IFIT1. | 2003 Oct |
1 |
| 39 |
12829242 | Phosphoinositide 3-kinase-dependent activation of Rac. | 2003 Jul 3 |
1 |
| 40 |
11961559 | SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling. | 2002 Apr 18 |
4 |
| 41 |
12134164 | Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism. | 2002 Aug |
1 |
| 42 |
12177507 | The two hats of SOS. | 2002 Aug 13 |
1 |
| 43 |
12192056 | Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. | 2002 Sep |
1 |
| 44 |
11158304 | Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1. | 2001 Feb |
1 |
| 45 |
11524436 | An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine. | 2001 Sep 3 |
3 |
| 46 |
10655614 | The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI. | 2000 Feb |
1 |
| 47 |
10499589 | EPS8 and E3B1 transduce signals from Ras to Rac. | 1999 Sep 16 |
1 |
| 48 |
10579721 | Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. | 1999 Nov 29 |
1 |
| 49 |
9422735 | The small GTP-binding protein Rac promotes the dissociation of gelsolin from actin filaments in neutrophils. | 1998 Jan 9 |
1 |
| 50 |
9796702 | p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes. | 1998 Oct 1 |
1 |