Hydrogen Peroxide

AKT serine/threonine kinase 1 ; Homo sapiens







271 Article(s)
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151 23528356 Mechanisms underlying protective effects of trimetazidine on endothelial progenitor cells biological functions against H2O2-induced injury: involvement of antioxidation and Akt/eNOS signaling pathways. 2013 May 5 1
152 23533502 Novel bioactivity of ellagic Acid in inhibiting human platelet activation. 2013 1
153 23535373 Exercise ameliorates cognition impairment due to restraint stress-induced oxidative insult and reduced BDNF level. 2013 May 3 4
154 23555559 Critical role of H2O2 generated by NOX4 during cellular response under glucose deprivation. 2013 2
155 23624332 Integrin-linked kinase mediates the hydrogen peroxide-dependent transforming growth factor-β1 up-regulation. 2013 Aug 1
156 23643711 Hydrogen peroxide production regulates the mitochondrial function in insulin resistant muscle cells: effect of catalase overexpression. 2013 Oct 1
157 23660824 Salidroside protects against hydrogen peroxide-induced injury in HUVECs via the regulation of REDD1 and mTOR activation. 2013 Jul 2
158 23685151 Hydrogen peroxide inhibits transforming growth factor-β1-induced cell cycle arrest by promoting Smad3 linker phosphorylation through activation of Akt-ERK1/2-linked signaling pathway. 2013 Jun 14 2
159 23685908 Role of LM23 in cell proliferation and apoptosis and its expression during the testis development. 2013 Jul 1
160 23726950 Macrophage-stimulating protein attenuates hydrogen peroxide-induced apoptosis in human renal HK-2 cells. 2013 Sep 5 2
161 23750203 Protective effects of andrographolide analogue AL-1 on ROS-induced RIN-mβ cell death by inducing ROS generation. 2013 1
162 23805040 Oxidative stress response signaling pathways in trabecular meshwork cells and their effects on cell viability. 2013 2
163 23837937 Sphingosine 1-phosphate attenuates peroxide-induced apoptosis in HaCaT cells cultured in vitro. 2013 Aug 3
164 23845990 Role of PTHrP in human intestinal Caco-2 cell response to oxidative stress. 2013 Dec 1
165 23849871 Effects of H2O2 on insulin signaling the glucose transport system in mammalian skeletal muscle. 2013 1
166 23954465 Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth. 2013 Nov 1 1
167 24042352 Oxidative stress induces proliferation of colorectal cancer cells by inhibiting RUNX3 and activating the Akt signaling pathway. 2013 Nov 3
168 24064382 Oxidative stress enhances Axl-mediated cell migration through an Akt1/Rac1-dependent mechanism. 2013 Dec 3
169 24151624 7,8-Dihydroxyflavone suppresses oxidative stress-induced base modification in DNA via induction of the repair enzyme 8-oxoguanine DNA glycosylase-1. 2013 1
170 24152913 Fenobam promoted the neuroprotective effect of PEP-1-FK506BP following oxidative stress by increasing its transduction efficiency. 2013 Nov 1
171 22020565 Diallyl trisulfide-induced prostate cancer cell death is associated with Akt/PKB dephosphorylation mediated by P-p66shc. 2012 Oct 1
172 22420665 Luteolin inhibited hydrogen peroxide-induced vascular smooth muscle cells proliferation and migration by suppressing the Src and Akt signalling pathways. 2012 Apr 3
173 22492997 DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway. 2012 Jul 1 1
174 22507555 Cytoprotective and anti-inflammatory effects of melatonin in hydrogen peroxide-stimulated CHON-001 human chondrocyte cell line and rabbit model of osteoarthritis via the SIRT1 pathway. 2012 Oct 1
175 22566145 Phytosphingosine-1-phosphate represses the hydrogen peroxide-induced activation of c-Jun N-terminal kinase in human dermal fibroblasts through the phosphatidylinositol 3-kinase/Akt pathway. 2012 Oct 2
176 22580126 Inhibition of hydrogen peroxide signaling by 4-hydroxynonenal due to differential regulation of Akt1 and Akt2 contributes to decreases in cell survival and proliferation in hepatocellular carcinoma cells. 2012 Jul 1 4
177 22749807 Maintenance of higher H₂O₂ levels, and its mechanism of action to induce growth in breast cancer cells: important roles of bioactive catalase and PP2A. 2012 Oct 15 2
178 22763095 Sphingosine-1-phosphate inhibits H2O2-induced granulosa cell apoptosis via the PI3K/Akt signaling pathway. 2012 Oct 1
179 22796327 Proline dehydrogenase is essential for proline protection against hydrogen peroxide-induced cell death. 2012 Sep 1 1
180 22797316 Hydrogen peroxide attenuates the prosurvival signaling of insulin-like growth factor-1 through two pathways. 2012 Sep 12 1
181 22886427 Neuregulin-1 suppresses cardiomyocyte apoptosis by activating PI3K/Akt and inhibiting mitochondrial permeability transition pore. 2012 Nov 1
182 20965163 Honokiol inhibits H(2)O(2)-induced apoptosis in human lens epithelial cells via inhibition of the mitogen-activated protein kinase and Akt pathways. 2011 Jan 10 3
183 21237235 The neuroprotective effects of Lonicera japonica THUNB. against hydrogen peroxide-induced apoptosis via phosphorylation of MAPKs and PI3K/Akt in SH-SY5Y cells. 2011 Apr 2
184 21239473 The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth. 2011 Mar 1 1
185 21300705 Nortriptyline reverses corticosteroid insensitivity by inhibition of phosphoinositide-3-kinase-δ. 2011 May 1
186 21315693 Preventing H₂O₂-induced apoptosis in cerebellar granule neurons by regulating the VEGFR-2/Akt signaling pathway using a novel dimeric antiacetylcholinesterase bis(12)-hupyridone. 2011 Jun 7 2
187 21397862 Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors. 2011 Mar 8 1
188 21418589 The scavenging of superoxide radicals promotes apoptosis induced by a novel cell-permeable fusion protein, sTRAIL:FeSOD, in tumor necrosis factor-related apoptosis-inducing ligand-resistant leukemia cells. 2011 Mar 19 1
189 21452000 Oxidative stress is closely associated with tumor angiogenesis of hepatocellular carcinoma. 2011 Jun 1
190 21467197 Ghrelin inhibits hydrogen peroxide-induced apoptotic cell death of oligodendrocytes via ERK and p38MAPK signaling. 2011 Jun 1
191 21643999 Expression of pancreatitis-associated protein after traumatic brain injury: a mechanism potentially contributing to neuroprotection in human brain. 2011 Nov 1
192 21742779 Chelation of lysosomal iron protects dopaminergic SH-SY5Y neuroblastoma cells from hydrogen peroxide toxicity by precluding autophagy and Akt dephosphorylation. 2011 Oct 1
193 21979951 Akt2 kinase suppresses glyceraldehyde-3-phosphate dehydrogenase (GAPDH)-mediated apoptosis in ovarian cancer cells via phosphorylating GAPDH at threonine 237 and decreasing its nuclear translocation. 2011 Dec 9 1
194 22102892 Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes. 2011 2
195 19962976 Catalpol inhibits apoptosis in hydrogen peroxide-induced endothelium by activating the PI3K/Akt signaling pathway and modulating expression of Bcl-2 and Bax. 2010 Feb 25 2
196 20133695 DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway. 2010 Feb 16 1
197 20142804 Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells. 2010 May 1
198 20145959 Gamma-glutamyl 16-diaminopropane derivative of vasoactive intestinal peptide: a potent anti-oxidative agent for human epidermoid cancer cells. 2010 Aug 1
199 20211239 Downregulation of mitochondrial telomerase reverse transcriptase induced by H2O2 is Src kinase dependent. 2010 Aug 1
200 21103079 Significance of p27 as potential biomarker for intracellular oxidative status. 2010 Oct 2