| 1 |
34854518 | The unique Akt inhibitor SC66 suppressed AMPK activity and abolished autophagy through the EGFR-p62 pathway. | 2022 Feb |
1 |
| 2 |
34949154 | 24-Dehydrocholesterol Reductase alleviates oxidative damage-induced apoptosis in alveolar epithelial cells via regulating Phosphatidylinositol-3-Kinase/Protein Kinase B activation. | 2022 Jan |
1 |
| 3 |
35085541 | Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo. | 2022 Mar |
1 |
| 4 |
35198094 | Luteolin Alleviates Epithelial-Mesenchymal Transformation Induced by Oxidative Injury in ARPE-19 Cell via Nrf2 and AKT/GSK-3β Pathway. | 2022 |
2 |
| 5 |
35204748 | Inflammation Promotes Oxidative and Nitrosative Stress in Chronic Myelogenous Leukemia. | 2022 Feb 3 |
1 |
| 6 |
35222803 | Protection of Human Lens Epithelial Cells from Oxidative Stress Damage and Cell Apoptosis by KGF-2 through the Akt/Nrf2/HO-1 Pathway. | 2022 |
1 |
| 7 |
35387349 | Metformin Promotes Differentiation and Attenuates H2O2-Induced Oxidative Damage of Osteoblasts via the PI3K/AKT/Nrf2/HO-1 Pathway. | 2022 |
2 |
| 8 |
35400456 | Combined RNA-seq and molecular biology technology revealed the protective effect of Cyclocarya paliurus polysaccharide on H2O2-induced oxidative damage in L02 cells thought regulating mitochondrial function, oxidative stress and PI3K/Akt and MAPK signaling pathways. | 2022 May |
1 |
| 9 |
35499687 | Interplay between PI3K/AKT pathway and heart disorders. | 2022 May 2 |
1 |
| 10 |
35543385 | Recombinant human klotho protects against hydrogen peroxide-mediated injury in human retinal pigment epithelial cells via the PI3K/Akt-Nrf2/HO-1 signaling pathway. | 2022 May |
1 |
| 11 |
32794021 | Homocysteine-induced decrease in HUVEC cells' resistance to oxidative stress is mediated by Akt-dependent changes in iron metabolism. | 2021 Apr |
1 |
| 12 |
33111210 | 6,4'-dihydroxy-7-methoxyflavanone protects against H2O2-induced cellular senescence by inducing SIRT1 and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation. | 2021 Feb |
3 |
| 13 |
33226571 | Melatonin upregulates DNA-PKcs to suppress apoptosis of human umbilical vein endothelial cells via inhibiting miR-101 under H2O2-induced oxidative stress. | 2021 Feb |
4 |
| 14 |
33385639 | Tectorigenin protect HUVECs from H2O2-induced oxidative stress injury by regulating PI3K/Akt pathway. | 2021 Feb |
4 |
| 15 |
33393627 | Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway. | 2021 Jan 29 |
2 |
| 16 |
33521822 | Exploring the mechanism of (-)-Epicatechin on premature ovarian insufficiency based on network pharmacology and experimental evaluation. | 2021 Feb 26 |
1 |
| 17 |
33545736 | Protocatechuic Acid Protects Platelets from Apoptosis via Inhibiting Oxidative Stress-Mediated PI3K/Akt/GSK3β Signaling. | 2021 Jul |
1 |
| 18 |
33775716 | The signaling pathway PI3K/Akt/Nrf2/HO-1 plays a role in the mitochondrial protection promoted by astaxanthin in the SH-SY5Y cells exposed to hydrogen peroxide. | 2021 Jun |
3 |
| 19 |
33793833 | Fluvastatin protects neuronal cells from hydrogen peroxide-induced toxicity with decreasing oxidative damage and increasing PI3K/Akt/mTOR signalling. | 2021 Mar 8 |
1 |
| 20 |
33915898 | MicroRNA-100 Mediates Hydrogen Peroxide-Induced Apoptosis of Human Retinal Pigment Epithelium ARPE-19 Cells. | 2021 Apr 1 |
1 |
| 21 |
34077701 | Formononetin attenuates H2O2-induced cell death through decreasing ROS level by PI3K/Akt-Nrf2-activated antioxidant gene expression and suppressing MAPK-regulated apoptosis in neuronal SH-SY5Y cells. | 2021 Jul |
1 |
| 22 |
34091997 | AQP3-mediated H2 O2 uptake inhibits LUAD autophagy by inactivating PTEN. | 2021 Aug |
1 |
| 23 |
34316226 | Hydrogen Peroxide Has Adverse Effects on Human Sperm Quality Parameters, Induces Apoptosis, and Reduces Survival. | 2021 Apr-Jun |
1 |
| 24 |
34394836 | Leonurine Ameliorates Oxidative Stress and Insufficient Angiogenesis by Regulating the PI3K/Akt-eNOS Signaling Pathway in H2O2-Induced HUVECs. | 2021 |
1 |
| 25 |
34558653 | Ginsenoside Rk1 protects human melanocytes from H2O2‑induced oxidative injury via regulation of the PI3K/AKT/Nrf2/HO‑1 pathway. | 2021 Nov |
2 |
| 26 |
34769014 | Isoform-Specific Effects of Apolipoprotein E on Hydrogen Peroxide-Induced Apoptosis in Human Induced Pluripotent Stem Cell (iPSC)-Derived Cortical Neurons. | 2021 Oct 27 |
1 |
| 27 |
34873406 | Quercetin Improves Mitochondrial Function and Inflammation in H2O2-Induced Oxidative Stress Damage in the Gastric Mucosal Epithelial Cell by Regulating the PI3K/AKT Signaling Pathway. | 2021 |
1 |
| 28 |
31698268 | Monotropein attenuates oxidative stress via Akt/mTOR-mediated autophagy in osteoblast cells. | 2020 Jan |
1 |
| 29 |
31940823 | Airborne Particulate Matter (PM10) Inhibits Apoptosis through PI3K/AKT/FoxO3a Pathway in Lung Epithelial Cells: The Role of a Second Oxidant Stimulus. | 2020 Jan 11 |
1 |
| 30 |
32043704 | Repression of Kisspeptin1 weakens hydrogen peroxide-caused injury in HTR8 cells via adjusting PI3K/AKT/mTOR pathway. | 2020 May |
2 |
| 31 |
32271398 | VO-OHpic attenuates intervertebral disc degeneration via PTEN/Akt pathway. | 2020 Mar |
1 |
| 32 |
32387419 | Antioxidant properties and neuroprotective effects of Esc-1GN through the regulation of MAPK and AKT signaling. | 2020 Aug 1 |
1 |
| 33 |
32471716 | MDM2 phosphorylation mediates H2O2-induced lens epithelial cells apoptosis and age-related cataract. | 2020 Jul 12 |
1 |
| 34 |
32556702 | A Novel Compound YS-5-23 Exhibits Neuroprotective Effect by Reducing β-Site Amyloid Precursor Protein Cleaving Enzyme 1's Expression and H2O2-Induced Cytotoxicity in SH-SY5Y Cells. | 2020 Sep |
1 |
| 35 |
32590330 | Differential endothelial signaling responses elicited by chemogenetic H2O2 synthesis. | 2020 Sep |
1 |
| 36 |
32598944 | Artemisinin protects motoneurons against axotomy-induced apoptosis through activation of the PKA-Akt signaling pathway and promotes neural stem/progenitor cells differentiation into NeuN+ neurons. | 2020 Sep |
2 |
| 37 |
32678390 | Amino acid modified gadofullerene protects against insulin resistance induced by oxidative stress in 3T3-L1 adipocytes. | 2020 Aug 26 |
1 |
| 38 |
32774685 | Tribulus terrestris Ameliorates Oxidative Stress-Induced ARPE-19 Cell Injury through the PI3K/Akt-Nrf2 Signaling Pathway. | 2020 |
1 |
| 39 |
32860809 | Puerarin attenuates the endothelial-mesenchymal transition induced by oxidative stress in human coronary artery endothelial cells through PI3K/AKT pathway. | 2020 Nov 5 |
1 |
| 40 |
32881386 | SHIP2 inhibition alters redox-induced PI3K/AKT and MAP kinase pathways via PTEN over-activation in cervical cancer cells. | 2020 Oct |
1 |
| 41 |
33002038 | Thermal cycling protects SH-SY5Y cells against hydrogen peroxide and β-amyloid-induced cell injury through stress response mechanisms involving Akt pathway. | 2020 |
1 |
| 42 |
33101583 | Reactive Oxygen Species Induce Endothelial Differentiation of Liver Cancer Stem-Like Sphere Cells through the Activation of Akt/IKK Signaling Pathway. | 2020 |
2 |
| 43 |
30456590 | Epigallocatechin gallate suppresses premature senescence of preadipocytes by inhibition of PI3K/Akt/mTOR pathway and induces senescent cell death by regulation of Bax/Bcl-2 pathway. | 2019 Apr |
1 |
| 44 |
30485137 | ROS-induced autophagy regulates porcine trophectoderm cell apoptosis, proliferation, and differentiation. | 2019 Feb 1 |
1 |
| 45 |
30576222 | Klotho protein inhibits H2O2-induced oxidative injury in endothelial cells via regulation of PI3K/AKT/Nrf2/HO-1 pathways. | 2019 May |
2 |
| 46 |
30594603 | Lycium barbarum polysaccharides alleviate hydrogen peroxide-induced injury by up-regulation of miR-4295 in human trabecular meshwork cells. | 2019 Feb |
1 |
| 47 |
30669455 | Transfection with GLS2 Glutaminase (GAB) Sensitizes Human Glioblastoma Cell Lines to Oxidative Stress by a Common Mechanism Involving Suppression of the PI3K/AKT Pathway. | 2019 Jan 19 |
3 |
| 48 |
30689624 | Sulforaphane Attenuates H₂O₂-induced Oxidant Stress in Human Trabecular Meshwork Cells (HTMCs) via the Phosphatidylinositol 3-Kinase (PI3K)/Serine/Threonine Kinase (Akt)-Mediated Factor-E2-Related Factor 2 (Nrf2) Signaling Activation. | 2019 Jan 28 |
2 |
| 49 |
30690126 | The protective effects of vernicilignan A, a new flavonolignan isolated from Toxicodendron vernicifluum on SH-SY5Y cells against oxidative stress-induced injury. | 2019 Apr |
1 |
| 50 |
30697266 | Renin-angiotensin system inhibitor attenuates oxidative stress induced human coronary artery endothelial cell dysfunction via the PI3K/AKT/mTOR pathway. | 2019 Jan |
4 |