desloratadine

cytochrome P450 family 2 subfamily C member 8 ; Homo sapiens







5 Article(s)
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Pub. Year
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1 32970826 Clopidogrel Dosing: Current Successes and Emerging Factors for Further Consideration. 2021 May 1
2 33109037 A Randomized Study on the Bioequivalence of Desloratadine in Healthy Chinese Subjects and the Association of Different Metabolic Phenotypes With UGT2B10 and CYP2C8 Genotypes. 2020 1
3 30630815 Clopidogrel and Gemfibrozil Strongly Inhibit the CYP2C8-Dependent Formation of 3-Hydroxydesloratadine and Increase Desloratadine Exposure In Humans. 2019 Apr 5
4 25595597 A long-standing mystery solved: the formation of 3-hydroxydesloratadine is catalyzed by CYP2C8 but prior glucuronidation of desloratadine by UDP-glucuronosyltransferase 2B10 is an obligatory requirement. 2015 Apr 2
5 26135009 Further Characterization of the Metabolism of Desloratadine and Its Cytochrome P450 and UDP-glucuronosyltransferase Inhibition Potential: Identification of Desloratadine as a Relatively Selective UGT2B10 Inhibitor. 2015 Sep 1