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32857315 | Single-Dose Pharmacokinetics of Ozanimod and its Major Active Metabolites Alone and in Combination with Gemfibrozil, Itraconazole, or Rifampin in Healthy Subjects: A Randomized, Parallel-Group, Open-Label Study. | 2020 Oct |
1 |
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31420941 | Expanded Physiologically-Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion Transporting Polypeptide 1B Induction. | 2019 Nov |
1 |
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28715853 | Effect of gemfibrozil and rifampicin on the pharmacokinetics of selexipag and its active metabolite in healthy subjects. | 2017 Dec |
1 |
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24553381 | Evaluation of 23 lots of commercially available cryopreserved hepatocytes for induction assays of human cytochromes P450. | 2014 May |
1 |
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20086032 | Hepatocyte nuclear factor 4{alpha} regulates rifampicin-mediated induction of CYP2C genes in primary cultures of human hepatocytes. | 2010 Apr |
4 |
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16390353 | Effect of rifampicin on the pharmacokinetics of pioglitazone. | 2006 Jan |
1 |
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15676042 | Influence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes. | 2005 Feb |
2 |
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15771232 | Comparative effects of fibrates on drug metabolizing enzymes in human hepatocytes. | 2005 Jan |
1 |
| 9 |
15933212 | Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha. | 2005 Sep |
2 |
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16176562 | Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: effect of fibrates and rifampicin. | 2005 Oct |
2 |
| 11 |
15001966 | Effect of rifampin on the pharmacokinetics of rosiglitazone in healthy subjects. | 2004 Mar |
1 |
| 12 |
15371985 | Effects of trimethoprim and rifampin on the pharmacokinetics of the cytochrome P450 2C8 substrate rosiglitazone. | 2004 Sep |
5 |
| 13 |
12815172 | Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation. | 2003 Jul |
1 |
| 14 |
12040753 | Evaluation of gene induction of drug-metabolizing enzymes and transporters in primary culture of human hepatocytes using high-sensitivity real-time reverse transcription PCR. | 2002 May |
1 |
| 15 |
12130704 | Expression and induction of CYP2C P450 enzymes in primary cultures of human hepatocytes. | 2002 Aug |
1 |
| 16 |
11181490 | Induction of CYP2C genes in human hepatocytes in primary culture. | 2001 Mar |
4 |
| 17 |
11714868 | Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays. | 2001 Dec |
1 |
| 18 |
10924340 | Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes. | 2000 Aug 11 |
1 |