Quinones

NAD(P)H quinone dehydrogenase 1 ; Homo sapiens







173 Article(s)
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151 7620214 Enzyme-directed bioreductive drug development revisited: a commentary on recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes, particularly DT-diaphorase. 1994 1
152 7620217 Bioactivation of quinones by DT-diaphorase, molecular, biochemical, and chemical studies. 1994 1
153 7620221 NAD(P)H:quinone oxidoreductase1 (DT-diaphorase): expression, regulation, and role in cancer. 1994 3
154 8004128 Jun and Fos regulation of NAD(P)H: quinone oxidoreductase gene expression. 1994 Feb 2
155 8033096 Increased activity and expression of NAD(P)H:quinone acceptor oxidoreductase in confluent cell cultures and within multicellular spheroids. 1994 Jul 15 1
156 8375015 NAD(P)H:quinone oxidoreductase1 (DT-diaphorase) expression in normal and tumor tissues. 1993 Jun 3
157 8375023 DT-diaphorase in activation and detoxification of quinones. Bioreductive activation of mitomycin C. 1993 Jun 1
158 1324793 Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: relationship to the response of lung tumor xenografts to mitomycin Cł. 1992 Sep 1 1
159 1510692 The sensitivity of human tumour cells to quinone bioreductive drugs: what role for DT-diaphorase? 1992 Aug 4 1
160 1737339 NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity. 1992 Feb 15 1
161 1651729 High levels of expression of the NAD(P)H:quinone oxidoreductase (NQO1) gene in tumor cells compared to normal cells of the same origin. 1991 Aug 8 1
162 1714284 The role of NAD(P)H: quinone reductase (EC 1.6.99.2, DT-diaphorase) in the reductive bioactivation of the novel indoloquinone antitumor agent EO9. 1991 Jul 1
163 1777518 [Interaction of menadione and duroquinone with Q-cycle during DT-diaphorase function]. 1991 Oct 1
164 1899380 The human dioxin-inducible NAD(P)H: quinone oxidoreductase cDNA-encoded protein expressed in COS-1 cells is identical to diaphorase 4. 1991 Jan 1 2
165 2113030 Activation and deactivation of quinones catalyzed by DT-diaphorase. Evidence for bioreductive activation of diaziquone (AZQ) in human tumor cells and detoxification of benzene metabolites in bone marrow stroma. 1990 1
166 2307529 Cytosolic NAD(P)H:(quinone-acceptor)oxidoreductase in human normal and tumor tissue: effects of cigarette smoking and alcohol. 1990 Mar 15 1
167 2539822 The toxicity of menadione and mitozantrone in human liver-derived Hep G2 hepatoma cells. 1989 Apr 15 1
168 2843525 Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16. 1988 Sep 25 1
169 2425252 Somatic mutation, DNA damage and cytotoxicity induced by benzo[a]pyrenedione/benzo[a]pyrenediol redox couples in cultured mammalian cells. 1986 Jul 1
170 4060194 Induction of cell damage by menadione and benzo(a)pyrene-3,6-quinone in cultures of adult rat hepatocytes and human fibroblasts. 1985 Oct 1
171 6584903 Mutagenicity of quinones: pathways of metabolic activation and detoxification. 1984 Mar 1
172 6313461 Futile redox cycling: implications for oxygen radical toxicity. 1983 Jul-Aug 2
173 6181068 The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells. 1982 Oct 25 1