Acetyl Coenzyme A

ATP citrate lyase ; Homo sapiens







84 Article(s)
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1 34716958 Nuclear FABP7 regulates cell proliferation of wild-type IDH1 glioma through caveolae formation. 2022 Jan 1
2 35177584 Nanog mediated by FAO/ACLY signaling induces cellular dormancy in colorectal cancer cells. 2022 Feb 17 1
3 35316657 The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming. 2022 Apr 5 1
4 35385700 Sugar addiction: An Achilles' heel of auto-immune diseases? 2022 Apr 5 1
5 35402505 A Nutrient-Based Cellular Model to Characterize Acetylation-Dependent Protein-Protein Interactions. 2022 2
6 35436171 ATP-citrate lyase (ACLY) inhibitors as therapeutic agents: a patenting perspective. 2022 Jul 2
7 32448086 Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study. 2021 Jul 3
8 33679780 Exploring the Role of ATP-Citrate Lyase in the Immune System. 2021 3
9 34155695 Inhibition of ACLY Leads to Suppression of Osteoclast Differentiation and Function Via Regulation of Histone Acetylation. 2021 Oct 4
10 34179312 ITGA2 promotes expression of ACLY and CCND1 in enhancing breast cancer stemness and metastasis. 2021 Jul 2
11 34205266 Myeloid-Specific Acly Deletion Alters Macrophage Phenotype In Vitro and In Vivo without Affecting Tumor Growth. 2021 Jun 19 3
12 34205414 Understanding the Central Role of Citrate in the Metabolism of Cancer Cells and Tumors: An Update. 2021 Jun 19 1
13 34294920 Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. 2021 Aug 1
14 34294921 Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. 2021 Aug 1
15 34323067 Regulation on Citrate Influx and Metabolism through Inhibiting SLC13A5 and ACLY: A Novel Mechanism Mediating the Therapeutic Effects of Curcumin on NAFLD. 2021 Aug 11 2
16 34375734 Disturbed mitochondrial acetylation in accordance with the availability of acetyl groups in hepatocellular carcinoma. 2021 Sep 2
17 34573442 Mammalian SIRT6 Represses Invasive Cancer Cell Phenotypes through ATP Citrate Lyase (ACLY)-Dependent Histone Acetylation. 2021 Sep 21 6
18 34620845 ATP-citrate lyase promotes axonal transport across species. 2021 Oct 7 4
19 34635427 The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis. 2021 Dec 1
20 34831186 ACLY Nuclear Translocation in Human Macrophages Drives Proinflammatory Gene Expression by NF-κB Acetylation. 2021 Oct 30 4
21 31499095 ATP-citrate lyase (ACLY) in lipid metabolism and atherosclerosis: An updated review. 2020 Jan 2
22 31830561 ATP citrate lyase: A central metabolic enzyme in cancer. 2020 Feb 28 1
23 31873304 Molecular basis for acetyl-CoA production by ATP-citrate lyase. 2020 Jan 7
24 31947614 The Drosophila Citrate Lyase Is Required for Cell Division during Spermatogenesis. 2020 Jan 14 2
25 32164290 Comparative Metabolites and Citrate-Degrading Enzymes Activities in Citrus Fruits Reveal the Role of Balance between ACL and Cyt-ACO in Metabolite Conversions. 2020 Mar 10 1
26 32242119 Author Correction: Molecular basis for acetyl-CoA production by ATP-citrate lyase. 2020 May 1
27 32420483 ACLY is the novel signaling target of PIP2/PIP3 and Lyn in acute myeloid leukemia. 2020 May 4
28 32525551 A Positive Feedback Loop Between c-Myc Upregulation, Glycolytic Shift, and Histone Acetylation Enhances Cancer Stem Cell-like Property and Tumorigenicity of Cr(VI)-transformed Cells. 2020 Sep 1 2
29 32808657 Acetyl-CoA Regulation, OXPHOS Integrity and Leptin Levels Are Different in Females With Childhood vs Adulthood Onset of Obesity. 2020 Nov 1 1
30 32849657 Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells. 2020 1
31 29883801 Glucose-derived acetate and ACSS2 as key players in cisplatin resistance in bladder cancer. 2019 Mar 1
32 30586346 Bempedoic acid: effects on lipoprotein metabolism and atherosclerosis. 2019 Feb 1
33 30626590 Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis. 2019 Mar 3
34 30853332 A role for ATP Citrate Lyase in cell cycle regulation during myeloid differentiation. 2019 May 2
35 30877197 ATP-citrate lyase multimerization is required for coenzyme-A substrate binding and catalysis. 2019 May 3 7
36 31141698 Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females. 2019 May 28 4
37 31150280 ATP-citrate lyase is an epigenetic regulator to promote obesity-related kidney injury. 2019 Aug 4
38 31411782 Identification of the active site residues in ATP-citrate lyase's carboxy-terminal portion. 2019 Oct 1
39 29395431 ATP Citrate Lyase: A New Player Linking Skeletal Muscle Metabolism and Epigenetics. 2018 Apr 1
40 29674394 Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+-NFAT signaling. 2018 Apr 1 4
41 29929979 Modulation of matrix metabolism by ATP-citrate lyase in articular chondrocytes. 2018 Aug 3 3
42 30195238 ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism. 2018 Sep 5 3
43 27997879 Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase. 2017 Jan 27 2
44 28059952 ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia. 2017 Apr 1
45 28129980 Discovery of furan carboxylate derivatives as novel inhibitors of ATP-citrate lyase via virtual high-throughput screening. 2017 Feb 15 2
46 28167750 ACSS2-mediated acetyl-CoA synthesis from acetate is necessary for human cytomegalovirus infection. 2017 Feb 21 5
47 28490526 ATP-citrate lyase is essential for high glucose-induced histone hyperacetylation and fibrogenic gene upregulation in mesangial cells. 2017 Aug 1 1
48 28689661 Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination. 2017 Jul 20 1
49 28732204 Put Your Mark Where Your Damage Is: Acetyl-CoA Production by ACLY Promotes DNA Repair. 2017 Jul 20 2
50 28993031 Targeting ATP-Citrate Lyase in Hyperlipidemia and Metabolic Disorders. 2017 Nov 2