8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid

ATP citrate lyase ; Homo sapiens







30 Article(s)
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1 34800002 Pharmacokinetics of bempedoic acid in patients with renal impairment. 2022 Mar 1
2 34981622 Bempedoic acid in patients with type 2 diabetes mellitus, prediabetes, and normoglycaemia: A post hoc analysis of efficacy and glycaemic control using pooled data from phase 3 clinical trials. 2022 May 2
3 35143133 [Bempedoïc acid, new cholesterol-lowering drug]. 2022 Feb 1
4 35619668 Bempedoic acid: a novel oral LDL-cholesterol lowering agent. 2022 2
5 33399194 Bempedoic acid: Review of a novel therapy in lipid management. 2021 Jan 5 2
6 33502687 Bempedoic Acid in the Treatment of Patients with Dyslipidemias and Statin Intolerance. 2021 Aug 2
7 33818688 Role of Bempedoic Acid in Clinical Practice. 2021 Aug 1
8 33847313 [Bempedoic acid: mechanism of action]. 2021 Apr 4
9 34075028 IGF1-mediated HOXA13 overexpression promotes colorectal cancer metastasis through upregulating ACLY and IGF1R. 2021 Jun 1 1
10 34172394 Lipid lowering with bempedoic acid added to a proprotein convertase subtilisin/kexin type 9 inhibitor therapy: A randomized, controlled trial. 2021 Jul-Aug 1
11 34435333 Bempedoic Acid: A New Non-statin Drug for the Treatment of Dyslipidemia. 2021 Oct 1
12 34448822 Pharmacodynamic effect of bempedoic acid and statin combinations: predictions from a dose-response model. 2021 Aug 27 1
13 34635427 The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis. 2021 Dec 4
14 34839358 ONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY. 2021 Nov 27 1
15 34909677 ATP citrate lyase inhibitor Bempedoic Acid alleviate long term HFD induced NASH through improvement in glycemic control, reduction of hepatic triglycerides & total cholesterol, modulation of inflammatory & fibrotic genes and improvement in NAS score. 2021 6
16 31499095 ATP-citrate lyase (ACLY) in lipid metabolism and atherosclerosis: An updated review. 2020 Jan 4
17 32564642 Bempedoic acid, an inhibitor of ATP citrate lyase for the treatment of hypercholesterolemia: early indications and potential. 2020 Aug 1
18 32763847 Measurement of bempedoic acid and its keto metabolite in human plasma and urine using solid phase extraction and electrospray LC-MS/MS. 2020 Oct 1 1
19 32980290 Bempedoic acid safety analysis: Pooled data from four phase 3 clinical trials. 2020 Sep - Oct 1
20 33025951 Bempedoic acid: effect of ATP-citrate lyase inhibition on low-density lipoprotein cholesterol and other lipids. 2020 Sep 4
21 33276805 Efficacy and safety of bempedoic acid alone or combining with other lipid-lowering therapies in hypercholesterolemic patients: a meta-analysis of randomized controlled trials. 2020 Dec 4 1
22 29939848 Bempedoic Acid (ETC-1002): ATP Citrate Lyase Inhibitor: Review of a First-in-Class Medication with Potential Benefit in Statin-Refractory Cases. 2019 Jan/Feb 2
23 30586346 Bempedoic acid: effects on lipoprotein metabolism and atherosclerosis. 2019 Feb 3
24 30865796 Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol. 2019 Mar 14 1
25 30922146 Efficacy and Safety of Bempedoic Acid in Patients With Hypercholesterolemia and Statin Intolerance. 2019 Apr 2 1
26 31906686 Current and future trends in the treatment of dyslipidemias. 2019 Winter 1
27 28059952 ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia. 2017 Apr 2
28 27663902 Bempedoic Acid (ETC-1002): an Investigational Inhibitor of ATP Citrate Lyase. 2016 Oct 6
29 27892461 Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis. 2016 Nov 28 5
30 26073398 Adenosine triphosphate citrate lyase: Emerging target in the treatment of dyslipidemia. 2015 May-Jun 1