quinone

cytochrome p450 oxidoreductase ; Homo sapiens







11 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 28214631 Discovery of quinone-directed antitumor agents selectively bioactivated by NQO1 over CPR with improved safety profile. 2017 Mar 31 1
2 23546588 [A pathophysiological role of cytochrome p450 involved in production of reactive oxygen species]. 2013 4
3 22205152 Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase: implications for increasing the activity against sensitive and multidrug-resistant leukaemia HL60 cells. 2012 Apr 1
4 15629867 9,10-Phenanthraquinone in diesel exhaust particles downregulates Cu,Zn-SOD and HO-1 in human pulmonary epithelial cells: intracellular iron scavenger 1,10-phenanthroline affords protection against apoptosis. 2005 Feb 1 1
5 8971136 Stable expression and coexpression of human cytochrome P450 oxidoreductase and cytochrome P450 1A2 in V79 Chinese hamster cells: sensitivity to quinones and biotransformation of 7-alkoxyresorufins and triazines. 1996 Dec 1
6 9101243 Enzymic- and thiol-mediated activation of halogen-substituted diaziridinylbenzoquinones: redox transitions of the semiquinone and semiquinone-thioether species. 1995 Mar 1
7 2536625 Hydroxyl radical generation and DNA strand scission mediated by natural anticancer and synthetic quinones. 1989 Jan 2 1
8 3023600 Interactions of anticancer quinone drugs, aclacinomycin A, adriamycin, carbazilquinone, and mitomycin C, with NADPH-cytochrome P-450 reductase, xanthine oxidase and oxygen. 1986 Aug 2
9 6295407 Generation of hydroxyl radical by anticancer quinone drugs, carbazilquinone, mitomycin C, aclacinomycin A and adriamycin, in the presence of NADPH-cytochrome P-450 reductase. 1982 Nov 15 2
10 6283813 Factors affecting the intracellular generation of free radicals from quinones. 1981 1
11 34156 NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals. 1979 Feb 1