| 1 |
35171619 | Thermodynamic Driving Forces of Redox-Dependent CPR Insertion into Biomimetic Endoplasmic Reticulum Membranes. | 2022 Mar 3 |
2 |
| 2 |
32866986 | Dual role of the active site 'lid' regions of protochlorophyllide oxidoreductase in photocatalysis and plant development. | 2021 Jan |
1 |
| 3 |
33011882 | Microsomal reductase activity in patients with thyroid neoplasms. | 2021 Jun |
1 |
| 4 |
33420418 | An electron transfer competent structural ensemble of membrane-bound cytochrome P450 1A1 and cytochrome P450 oxidoreductase. | 2021 Jan 8 |
2 |
| 5 |
31669572 | Differential effects of variations in human P450 oxidoreductase on the aromatase activity of CYP19A1 polymorphisms R264C and R264H. | 2020 Feb |
1 |
| 6 |
32708163 | Sensing the Generation of Intracellular Free Electrons Using the Inactive Catalytic Subunit of Cytochrome P450s as a Sink. | 2020 Jul 21 |
1 |
| 7 |
32994263 | Combined homozygous 21 hydroxylase with heterozygous P450 oxidoreductase mutation in a Saudi boy presented with hypertension. | 2020 Sep 29 |
5 |
| 8 |
33043019 | Oxidative Damage and Antioxidant Defense in Ferroptosis. | 2020 |
2 |
| 9 |
30427570 | Accurate Determination of Human CPR Conformational Equilibrium by smFRET Using Dual Orthogonal Noncanonical Amino Acid Labeling. | 2019 Mar 1 |
2 |
| 10 |
30883732 | Crystal structure of a NADPH-cytochrome P450 oxidoreductase (CYPOR) and heme oxygenase 1 fusion protein implies a conformational change in CYPOR upon NADPH/NADP+ binding. | 2019 Apr |
8 |
| 11 |
31249341 | Coupling of Redox and Structural States in Cytochrome P450 Reductase Studied by Molecular Dynamics Simulation. | 2019 Jun 27 |
2 |
| 12 |
31276316 | Rational evolution of the cofactor-binding site of cytochrome P450 reductase yields variants with increased activity towards specific cytochrome P450 enzymes. | 2019 Nov |
3 |
| 13 |
31749697 | Variability in Loss of Multiple Enzyme Activities Due to the Human Genetic Variation P284T Located in the Flexible Hinge Region of NADPH Cytochrome P450 Oxidoreductase. | 2019 |
1 |
| 14 |
29308883 | Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer. | 2018 Feb 13 |
6 |
| 15 |
29363234 | Stepwise Hydride Transfer in a Biological System: Insights into the Reaction Mechanism of the Light-Dependent Protochlorophyllide Oxidoreductase. | 2018 Mar 1 |
2 |
| 16 |
27032764 | Impact on CYP19A1 activity by mutations in NADPH cytochrome P450 oxidoreductase. | 2017 Jan |
2 |
| 17 |
27863990 | Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH-dependent lucigenin chemiluminescence in membrane assays. | 2017 Jan |
1 |
| 18 |
28188256 | MGDG, PG and SQDG regulate the activity of light-dependent protochlorophyllide oxidoreductase. | 2017 Mar 23 |
3 |
| 19 |
28347139 | Single-Protein Tracking Reveals That NADPH Mediates the Insertion of Cytochrome P450 Reductase into a Biomimetic of the Endoplasmic Reticulum. | 2017 Apr 19 |
4 |
| 20 |
28480030 | Drug-enhanced carbon monoxide production from heme by cytochrome P450 reductase. | 2017 Jan-Mar |
1 |
| 21 |
28618157 | Liver microsomal lipid enhances the activity and redox coupling of colocalized cytochrome P450 reductase-cytochrome P450 3A4 in nanodiscs. | 2017 Jul |
1 |
| 22 |
29148818 | Dissociation Constants of Cytochrome P450 2C9/Cytochrome P450 Reductase Complexes in a Lipid Bilayer Membrane Depend on NADPH: A Single-Protein Tracking Study. | 2017 Dec 13 |
3 |
| 23 |
29163152 | The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength. | 2017 |
1 |
| 24 |
26850353 | Isolation of the monooxygenase complex from Rhipicephalus (Boophilus) microplus - clues to understanding acaricide resistance. | 2016 Jun |
1 |
| 25 |
27285815 | Multiple active site residues are important for photochemical efficiency in the light-activated enzyme protochlorophyllide oxidoreductase (POR). | 2016 Aug |
1 |
| 26 |
27404282 | NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene. | 2016 Aug 15 |
2 |
| 27 |
27461959 | Role of active site loop in coenzyme binding and flavin reduction in cytochrome P450 reductase. | 2016 Sep 15 |
3 |
| 28 |
27558805 | NAD(P)H-dependent quinone oxidoreductase 1 (NQO1) and cytochrome P450 oxidoreductase (CYP450OR) differentially regulate menadione-mediated alterations in redox status, survival and metabolism in pancreatic β-cells. | 2016 Nov 16 |
2 |
| 29 |
27737328 | Long-term follow-up of a female with congenital adrenal hyperplasia due to P450-oxidoreductase deficiency. | 2016 Oct |
2 |
| 30 |
25728647 | Electron transfer by human wild-type and A287P mutant P450 oxidoreductase assessed by transient kinetics: functional basis of P450 oxidoreductase deficiency. | 2015 May 15 |
3 |
| 31 |
26066995 | Anion-Dependent Stimulation of CYP3A4 Monooxygenase. | 2015 Jul 7 |
1 |
| 32 |
26172514 | Nanodisc Films for Membrane Protein Studies by Neutron Reflection: Effect of the Protein Scaffold Choice. | 2015 Aug 4 |
1 |
| 33 |
26293521 | Interactions between CYP3A5*3 and POR*28 polymorphisms and lipid lowering response with atorvastatin. | 2015 Sep |
4 |
| 34 |
26361974 | Kinetic analysis of electron flux in cytochrome P450 reductases reveals differences in rate-determining steps in plant and mammalian enzymes. | 2015 Oct 15 |
3 |
| 35 |
24322786 | High warfarin sensitivity in carriers of CYP2C9*35 is determined by the impaired interaction with P450 oxidoreductase. | 2014 Aug |
3 |
| 36 |
24430948 | Lack of association of the p450 oxidoreductase *28 single nucleotide polymorphism with the lipid-lowering effect of statins in hypercholesterolemic patients. | 2014 Jun |
4 |
| 37 |
24589657 | Proximal FAD histidine residue influences interflavin electron transfer in cytochrome P450 reductase and methionine synthase reductase. | 2014 Apr 1 |
2 |
| 38 |
25196843 | Protein/protein interactions in the mammalian heme degradation pathway: heme oxygenase-2, cytochrome P450 reductase, and biliverdin reductase. | 2014 Oct 24 |
2 |
| 39 |
25517035 | The study of NADPH-dependent flavoenzyme-catalyzed reduction of benzo[1,2-c]1,2,5-oxadiazole N-oxides (benzofuroxans). | 2014 Dec 15 |
3 |
| 40 |
25521355 | POR*28 SNP is associated with lipid response to atorvastatin in children and adolescents with familial hypercholesterolemia. | 2014 Dec |
1 |
| 41 |
22809523 | Cytochrome P450 (CYP) enzymes and the development of CYP biosensors. | 2013 Jan 15 |
2 |
| 42 |
23332101 | Aromatic substitution of the FAD-shielding tryptophan reveals its differential role in regulating electron flux in methionine synthase reductase and cytochrome P450 reductase. | 2013 Mar |
2 |
| 43 |
23475681 | P450 oxidoreductase: genotyping, expression, purification of recombinant protein, and activity assessments of wild-type and mutant protein. | 2013 |
2 |
| 44 |
24196959 | Zinc finger nuclease knock-out of NADPH:cytochrome P450 oxidoreductase (POR) in human tumor cell lines demonstrates that hypoxia-activated prodrugs differ in POR dependence. | 2013 Dec 27 |
3 |
| 45 |
24299267 | Kinetic analysis of cytochrome P450 reductase from Artemisia annua reveals accelerated rates of NADH-dependent flavin reduction. | 2013 Dec |
2 |
| 46 |
24362093 | Oxidation of carcinogenic benzo[a]pyrene by human and rat cytochrome P450 1A1 and its influencing by cytochrome b5 - a comparative study. | 2013 |
1 |
| 47 |
22120726 | A novel microplate-based HPLC-fluorescence assay for determination of NADPH-cytochrome P450 reductase activity. | 2012 Sep |
1 |
| 48 |
22123124 | Effect of histidine-tag and R457H and E580Q mutations on catalytic activity of recombinant human cytochrome P450 oxidoreductase. | 2012 |
2 |
| 49 |
22205152 | Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase: implications for increasing the activity against sensitive and multidrug-resistant leukaemia HL60 cells. | 2012 Apr |
1 |
| 50 |
22543241 | The closed and compact domain organization of the 70-kDa human cytochrome P450 reductase in its oxidized state as revealed by NMR. | 2012 Jul 20 |
1 |