Flavin-Adenine Dinucleotide

⇄

cytochrome p450 oxidoreductase ; Homo sapiens







27 Article(s)
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1 32303637 Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches. 2020 May 29 2
2 31249341 Coupling of Redox and Structural States in Cytochrome P450 Reductase Studied by Molecular Dynamics Simulation. 2019 Jun 27 3
3 31276316 Rational evolution of the cofactor-binding site of cytochrome P450 reductase yields variants with increased activity towards specific cytochrome P450 enzymes. 2019 Nov 2
4 31445894 Short-lived neutral FMN and FAD semiquinones are transient intermediates in cryo-reduced yeast NADPH-cytochrome P450 reductase. 2019 Sep 30 2
5 31749697 Variability in Loss of Multiple Enzyme Activities Due to the Human Genetic Variation P284T Located in the Flexible Hinge Region of NADPH Cytochrome P450 Oxidoreductase. 2019 5
6 29308883 Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer. 2018 Feb 13 2
7 25728647 Electron transfer by human wild-type and A287P mutant P450 oxidoreductase assessed by transient kinetics: functional basis of P450 oxidoreductase deficiency. 2015 May 15 2
8 25832023 Membrane anchor of cytochrome P450 reductase suppresses the uncoupling of cytochrome P450. 2015 1
9 26361974 Kinetic analysis of electron flux in cytochrome P450 reductases reveals differences in rate-determining steps in plant and mammalian enzymes. 2015 Oct 15 2
10 24589657 Proximal FAD histidine residue influences interflavin electron transfer in cytochrome P450 reductase and methionine synthase reductase. 2014 Apr 1 2
11 23332101 Aromatic substitution of the FAD-shielding tryptophan reveals its differential role in regulating electron flux in methionine synthase reductase and cytochrome P450 reductase. 2013 Mar 5
12 21808038 Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency. 2011 Aug 16 1
13 19931102 Plant NADPH-cytochrome P450 oxidoreductases. 2010 Feb 1
14 20188793 Restoration of mutant cytochrome P450 reductase activity by external flavin. 2010 Jun 10 1
15 19483672 Structure of the open conformation of a functional chimeric NADPH cytochrome P450 reductase. 2009 Jul 1
16 18630181 [Antley-Bixler syndrome or POR deficiency?]. 2008 2
17 17505056 Differential inhibition of CYP17A1 and CYP21A2 activities by the P450 oxidoreductase mutant A287P. 2007 Aug 1
18 17635179 Clinical, structural and functional implications of mutations and polymorphisms in human NADPH P450 oxidoreductase. 2007 Aug 1
19 16391466 Decrease in NADPH-cytochrome P450 reductase activity of the human heart, Liver and lungs in the presence of alpha-lipoic acid. 2006 1
20 16998238 Diminished FAD binding in the Y459H and V492E Antley-Bixler syndrome mutants of human cytochrome P450 reductase. 2006 Nov 24 2
21 12779335 Preparation and characterization of a 5'-deazaFAD T491V NADPH-cytochrome P450 reductase. 2003 Jun 10 1
22 11673874 Characterization of hydride transfer to flavin adenine dinucleotide in neuronal nitric oxide synthase reductase domain: geometric relationship between the nicotinamide and isoalloxazine rings. 2001 Nov 1 4
23 9237990 Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes. 1997 Aug 5 3
24 7724541 Crystallization and preliminary x-ray studies of NADPH-cytochrome P450 reductase. 1995 Apr 11 2
25 7513993 Semi-artificial hydroxylating enzymes created by flavins binding to cytochrome P450 2B4 and by bleomycin binding to NADPH-cytochrome P450 reductase. 1994 Apr 29 1
26 1390631 Location of functional centers in the microsomal cytochrome P450 system. 1992 Sep 15 1
27 3099832 Localization of the free radical on the flavin mononucleotide of the air-stable semiquinone state of NADPH-cytochrome P-450 reductase using 31P NMR spectroscopy. 1986 Nov 4 1