| 1 |
33326752 | Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability. | 2021 Jan 5 |
2 |
| 2 |
35098008 | Maternal polymorphic loci of rs1979277 serine hydroxymethyl transferase and rs1805087 5-methylenetetrahydrofolate are correlated with the development of fetal growth restriction: A case-control study. | 2021 Dec |
1 |
| 3 |
31713293 | A SHMT1 variant decreases the risk of nonsyndromic cleft lip with or without cleft palate in Chile. | 2020 Jan |
2 |
| 4 |
32142918 | Drosha-independent miR-6778-5p strengthens gastric cancer stem cell stemness via regulation of cytosolic one-carbon folate metabolism. | 2020 May 28 |
1 |
| 5 |
30411815 | Serine hydroxymethyltransferase 1 promoter hypermethylation increases the risk of essential hypertension. | 2019 Mar |
2 |
| 6 |
30867454 | The 5-formyltetrahydrofolate futile cycle reduces pathway stochasticity in an extended hybrid-stochastic model of folate-mediated one-carbon metabolism. | 2019 Mar 13 |
6 |
| 7 |
29474406 | The role of the folate pathway in pancreatic cancer risk. | 2018 |
2 |
| 8 |
29953918 | Identification of three novel loci of ALDH2 Gene for Serum Folate levels in a Male Chinese Population by Genome-Wide Association Study. | 2018 Oct 20 |
1 |
| 9 |
30198140 | Vitamin D and folate: A reciprocal environmental association based on seasonality and genetic disposition. | 2018 Sep |
1 |
| 10 |
30378389 | The folic acid metabolism gene mel-32/Shmt is required for normal cell cycle lengths in Caenorhabditis elegans. | 2018 |
2 |
| 11 |
30500180 | Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties. | 2018 Dec 26 |
1 |
| 12 |
26950450 | Association of SHMT1 gene polymorphisms with the risk of childhood acute lymphoblastic leukemia in a sample of Iranian population. | 2016 Feb 29 |
2 |
| 13 |
27386562 | Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. | 2016 Jun |
1 |
| 14 |
25677305 | Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase. | 2015 Mar |
5 |
| 15 |
26666829 | SHMT1 C1420T polymorphism contributes to the risk of non-Hodgkin lymphoma: evidence from 7309 patients. | 2015 Dec 14 |
2 |
| 16 |
24362509 | DNMT3B C46359T and SHMT1 C1420T polymorphisms in the folate pathway in carcinogenesis of head and neck. | 2014 Feb |
2 |
| 17 |
24559276 | Plasma homocysteine levels and genetic polymorphisms in folate metablism are associated with breast cancer risk in chinese women. | 2014 Feb 21 |
2 |
| 18 |
25066213 | Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk. | 2014 Oct |
2 |
| 19 |
25194438 | Association between cytosolic serine hydroxymethyltransferase (SHMT1) gene polymorphism and cancer risk: a meta-analysis. | 2014 Jul |
1 |
| 20 |
22147344 | Oxidative stress is associated with genetic polymorphisms in one-carbon metabolism in coronary artery disease. | 2013 Nov |
1 |
| 21 |
23421317 | DHFR 19-bp deletion and SHMT C1420T polymorphisms and metabolite concentrations of the folate pathway in individuals with Down syndrome. | 2013 Apr |
6 |
| 22 |
21687976 | Polymorphism C1420T of Serine hydroxymethyltransferase gene on maternal risk for Down syndrome. | 2012 Mar |
4 |
| 23 |
22220685 | Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization. | 2012 Mar |
1 |
| 24 |
21178087 | Polymorphisms in serine hydroxymethyltransferase 1 and methylenetetrahydrofolate reductase interact to increase cardiovascular disease risk in humans. | 2011 Feb |
1 |
| 25 |
21371789 | In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed. | 2011 May |
1 |
| 26 |
19707223 | No association between cSHMT genotypes and the risk of breast cancer in the Nurses' Health Study. | 2010 Jan |
2 |
| 27 |
20386493 | Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate. | 2010 Jun |
1 |
| 28 |
19734144 | A UV-responsive internal ribosome entry site enhances serine hydroxymethyltransferase 1 expression for DNA damage repair. | 2009 Nov 6 |
1 |
| 29 |
17896178 | Polymorphism of cytosolic serine hydroxymethyltransferase, estrogen and breast cancer risk among Chinese women in Taiwan. | 2008 Sep |
2 |
| 30 |
17420066 | Polymorphisms of cytosolic serine hydroxymethyltransferase and risk of lung cancer: a case-control analysis. | 2007 Aug |
1 |
| 31 |
17446168 | Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway. | 2007 Jun 15 |
7 |
| 32 |
17482557 | Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells. | 2007 Jun 1 |
2 |
| 33 |
17702748 | A ferritin-responsive internal ribosome entry site regulates folate metabolism. | 2007 Oct 12 |
2 |
| 34 |
18067453 | Small ubiquitin-like modifier-1 (SUMO-1) modification of thymidylate synthase and dihydrofolate reductase. | 2007 |
2 |
| 35 |
16536979 | [Correlations between serine hydroxymethyltransferase1 C1420T polymorphisms and susceptibilities to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma]. | 2006 Mar |
2 |
| 36 |
17074544 | Polymorphisms in folate metabolizing genes and risk for spontaneous preterm and small-for-gestational age birth. | 2006 Nov |
2 |
| 37 |
15531579 | Mimosine attenuates serine hydroxymethyltransferase transcription by chelating zinc. Implications for inhibition of DNA replication. | 2005 Jan 7 |
1 |
| 38 |
16006999 | Polymorphisms and haplotypes of serine hydroxymethyltransferase and risk of squamous cell carcinoma of the head and neck: a case-control analysis. | 2005 Aug |
2 |
| 39 |
16046727 | Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men. | 2005 Aug |
2 |
| 40 |
15122597 | Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study. | 2004 Jul 1 |
1 |
| 41 |
15170323 | Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism. | 2004 Jun 8 |
2 |
| 42 |
12138190 | A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism. | 2002 Aug |
1 |
| 43 |
12161434 | Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses. | 2002 Oct 11 |
1 |
| 44 |
11305908 | Lack of catalytic activity of a murine mRNA cytoplasmic serine hydroxymethyltransferase splice variant: evidence against alternative splicing as a regulatory mechanism. | 2001 Apr 24 |
2 |
| 45 |
11386852 | Is mutated serine hydroxymethyltransferase (SHMT) involved in the etiology of neural tube defects? | 2001 Jun |
2 |
| 46 |
11516159 | The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by (13)C NMR. | 2001 Sep 1 |
1 |
| 47 |
10766749 | Mimosine is a cell-specific antagonist of folate metabolism. | 2000 Jun 23 |
2 |
| 48 |
8533763 | Haploinsufficiency of cytosolic serine hydroxymethyltransferase in the Smith-Magenis syndrome. | 1995 Dec |
1 |
| 49 |
7520695 | Interaction between glycine decarboxylase, serine hydroxymethyltransferase and tetrahydrofolate polyglutamates in pea leaf mitochondria. | 1994 Aug 15 |
2 |