5,6,7,8-tetrahydrofolic acid

serine hydroxymethyltransferase 1 ; Homo sapiens







21 Article(s)
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Pub. Year
#Total Relationships
1 30522268 Theoretical Evaluation of the Reaction Mechanism of Serine Hydroxymethyltransferase. 2019 Jan 17 4
2 30867454 The 5-formyltetrahydrofolate futile cycle reduces pathway stochasticity in an extended hybrid-stochastic model of folate-mediated one-carbon metabolism. 2019 Mar 13 2
3 31581160 High Expression of Serine Hydroxymethyltransferase 2 Indicates Poor Prognosis of Gastric Cancer Patients. 2019 Oct 3 2
4 29991441 Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes. 2018 Sep 1 2
5 30035852 The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells. 2018 Sep 4
6 30500180 Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties. 2018 Dec 26 2
7 28760597 Human and Plasmodium serine hydroxymethyltransferases differ in rate-limiting steps and pH-dependent substrate inhibition behavior. 2017 Sep 15 4
8 29073064 Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. 2017 Oct 24 2
9 25677305 Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase. 2015 Mar 2
10 24698160 Distinct biochemical properties of human serine hydroxymethyltransferase compared with the Plasmodium enzyme: implications for selective inhibition. 2014 Jun 1
11 22220685 Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization. 2012 Mar 2
12 21371789 In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed. 2011 May 2
13 16980404 Identification and biochemical characterization of serine hydroxymethyl transferase in the hydrogenosome of Trichomonas vaginalis. 2006 Dec 2
14 15170323 Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism. 2004 Jun 8 2
15 12514178 Pyridoxal phosphate inhibits dynamic subunit interchange among serine hydroxymethyltransferase tetramers. 2003 Mar 21 2
16 15044825 Cloning, expression, activity and folding studies of serine hydroxymethyltransferase: a target enzyme for cancer chemotherapy. 2003 2
17 11386852 Is mutated serine hydroxymethyltransferase (SHMT) involved in the etiology of neural tube defects? 2001 Jun 4
18 9753690 The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy. 1998 Sep 15 1
19 8786078 Characterisation of a human serine hydroxymethyltransferase pseudogene and its localisation to 1p32.3-33. 1996 Mar 2
20 1532227 Characterization of the formate (for) locus, which encodes the cytosolic serine hydroxymethyltransferase of Neurospora crassa. 1992 Apr 1
21 6776288 Effect of methionine, glycine and serine on serine hydroxymethyltransferase activity in rat glioma and human neuroblastoma cells. 1980 1