| 1 |
33228044 | Binding Studies of AICAR and Human Serum Albumin by Spectroscopic, Theoretical, and Computational Methodologies. | 2020 Nov 19 |
1 |
| 2 |
31431503 | The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 via pyrimidine depletion. | 2019 Oct 18 |
1 |
| 3 |
29773845 | AICAR inhibits NFκB DNA binding independently of AMPK to attenuate LPS-triggered inflammatory responses in human macrophages. | 2018 May 17 |
1 |
| 4 |
30107094 | Preclinical evidence of the enhanced effectiveness of combined rapamycin and AICAR in reducing kidney cancer. | 2018 Nov |
1 |
| 5 |
27847321 | AICAR activates ER stress-dependent apoptosis in gallbladder cancer cells. | 2017 Jan 8 |
2 |
| 6 |
28407446 | Doping control study of AICAR in post-race urine and plasma samples from horses. | 2017 Sep |
2 |
| 7 |
28719670 | Suppressive effect of AMP-activated protein kinase on the epithelial-mesenchymal transition in retinal pigment epithelial cells. | 2017 |
1 |
| 8 |
29032594 | Implementation of AICAR analysis by GC-C-IRMS for anti-doping purposes. | 2017 Nov |
1 |
| 9 |
29247196 | AICAR suppresses TNF-α-induced complement factor B in RPE cells. | 2017 Dec 15 |
1 |
| 10 |
26446934 | New synthetic AICAR derivatives with enhanced AMPK and ACC activation. | 2016 Oct |
1 |
| 11 |
27103440 | AICAR induces AMPK-independent programmed necrosis in prostate cancer cells. | 2016 May 27 |
2 |
| 12 |
27170207 | AICAR Attenuates TNFα-Induced Inappropriate Secretion of Monocyte Chemoattractant Protein-1 and Adiponectin in 3T3-L1 Adipocytes. | 2016 Dec 1 |
1 |
| 13 |
27521792 | Adenosine monophosphate-activated protein kinase attenuates cardiomyocyte hypertrophy through regulation of FOXO3a/MAFbx signaling pathway. | 2016 Sep |
1 |
| 14 |
27562249 | AMPK-independent inhibition of human macrophage ER stress response by AICAR. | 2016 Aug 26 |
1 |
| 15 |
26109067 | Wnt/β-Catenin Mediates AICAR Effect to Increase GATA3 Expression and Inhibit Adipogenesis. | 2015 Aug 7 |
1 |
| 16 |
26286955 | Exercise-mimetic AICAR transiently benefits brain function. | 2015 Jul 30 |
1 |
| 17 |
24760559 | Determination of ¹³C/¹² C ratios of endogenous urinary 5-amino-imidazole-4-carboxamide 1β-D-ribofuranoside (AICAR). | 2014 Jun 15 |
2 |
| 18 |
24778186 | Identification of yeast and human 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAr) transporters. | 2014 Jun 13 |
2 |
| 19 |
24915467 | Rapamycin prevents strong phosphorylation of p53 on serine 46 and attenuates activation of the p53 pathway in A549 lung cancer cells exposed to actinomycin D. | 2014 Jul |
1 |
| 20 |
23018889 | Involvement of Akt2/protein kinase B β (PKBβ) in the 8-Cl-cAMP-induced cancer cell growth inhibition. | 2013 Apr |
1 |
| 21 |
23076989 | Functional analysis of missense mutations of OAT, causing gyrate atrophy of choroid and retina. | 2013 Jan |
1 |
| 22 |
23531513 | AICAR inhibits PPARγ during monocyte differentiation to attenuate inflammatory responses to atherogenic lipids. | 2013 Jun 1 |
1 |
| 23 |
21956774 | Metabolomics of the effect of AMPK activation by AICAR on human umbilical vein endothelial cells. | 2012 Jan |
1 |
| 24 |
22231556 | AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation. | 2012 Jan 8 |
1 |
| 25 |
22554803 | Augmentation of reduced folate carrier-mediated folate/antifolate transport through an antiport mechanism with 5-aminoimidazole-4-carboxamide riboside monophosphate. | 2012 Aug |
1 |
| 26 |
21479175 | An invertebrate hyperglycemic model for the identification of anti-diabetic drugs. | 2011 Mar 30 |
1 |
| 27 |
21795305 | The influence of the BRAF V600E mutation in thyroid cancer cell lines on the anticancer effects of 5-aminoimidazole-4-carboxamide-ribonucleoside. | 2011 Oct |
1 |
| 28 |
21918180 | Pharmacological AMP-kinase activators have compartment-specific effects on cell physiology. | 2011 Dec |
1 |
| 29 |
21945951 | The activation of the p53 pathway by the AMP mimetic AICAR is reduced by inhibitors of the ATM or mTOR kinases. | 2011 Nov-Dec |
1 |
| 30 |
20615388 | AICAR induces cyclooxygenase-2 expression through AMP-activated protein kinase-transforming growth factor-beta-activated kinase 1-p38 mitogen-activated protein kinase signaling pathway. | 2010 Oct 15 |
1 |
| 31 |
20664053 | AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells. | 2010 Oct 21 |
1 |
| 32 |
18473182 | Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5'-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR). | 2009 Jun |
2 |
| 33 |
19144636 | AMP-activated protein kinase is involved in neural stem cell growth suppression and cell cycle arrest by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and glucose deprivation by down-regulating phospho-retinoblastoma protein and cyclin D. | 2009 Mar 6 |
1 |
| 34 |
19190259 | Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status. | 2009 May |
1 |
| 35 |
17945190 | AICAR positively regulate glycogen synthase activity and LDL receptor expression through Raf-1/MEK/p42/44MAPK/p90RSK/GSK-3 signaling cascade. | 2008 Jan 15 |
1 |
| 36 |
18063805 | AMP-activated protein kinase phosphorylates transcription factors of the CREB family. | 2008 Feb |
2 |
| 37 |
18199594 | Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. | 2008 Mar |
1 |
| 38 |
18326758 | Implication of S-adenosylhomocysteine hydrolase in inhibition of TNF-alpha- and IL-1beta-induced expression of inflammatory mediators by AICAR in RPE cells. | 2008 Mar |
1 |
| 39 |
18801732 | AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver. | 2008 Dec 5 |
1 |
| 40 |
18031613 | AICAR inhibits proliferation and induced S-phase arrest, and promotes apoptosis in CaSki cells. | 2007 Dec |
1 |
| 41 |
15860681 | AICAR and hyperosmotic stress increase insulin-stimulated glucose transport. | 2005 Sep |
1 |
| 42 |
15910743 | AICAR suppresses IL-2 expression through inhibition of GSK-3 phosphorylation and NF-AT activation in Jurkat T cells. | 2005 Jul 1 |
1 |
| 43 |
15033479 | AICAR stimulates adiponectin and inhibits cytokines in adipose tissue. | 2004 Apr 9 |
1 |
| 44 |
15328001 | Stimulators of AMP-activated protein kinase inhibit the respiratory burst in human neutrophils. | 2004 Aug 27 |
1 |
| 45 |
15358229 | AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms. | 2004 Aug 13 |
1 |
| 46 |
12791703 | Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells. | 2003 Aug 22 |
1 |
| 47 |
11509501 | Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase. | 2001 Sep |
1 |
| 48 |
11554766 | Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line. | 2001 Sep 21 |
1 |
| 49 |
11016448 | 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes. | 2000 Oct |
2 |
| 50 |
2006182 | Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells. | 1991 Mar 15 |
1 |