cyanoginosin LR

protein phosphatase 2 phosphatase activator ; Homo sapiens







30 Article(s)
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1 34432352 Pretreatment with metformin prevents microcystin-LR-induced tau hyperphosphorylation via mTOR-dependent PP2A and GSK-3β activation. 2021 Dec 1
2 33038821 Microcystin-LR exposure results in aberrant spindles and induces apoptosis in porcine oocytes. 2020 Dec 1
3 33193609 Synergistic Effect of MC-LR and C-Terminal Truncated HBx on HepG2 Cells and Their Effects on PP2A Mediated Downstream Target of MAPK Signaling Pathway. 2020 3
4 29265921 MicroRNA expression profiling involved in MC-LR-induced hepatotoxicity using high-throughput sequencing analysis. 2018 1
5 29800835 Transformation of microcystin-LR and olefinic compounds by ferrate(VI): Oxidative cleavage of olefinic double bonds as the primary reaction pathway. 2018 Sep 15 2
6 29984889 Alpha4-overexpressing HL7702 cells can counteract microcystin-LR effects on cytoskeletal structure. 2018 Sep 1
7 26784437 HEK293 cells exposed to microcystin-LR show reduced protein phosphatase 2A activity and more stable cytoskeletal structure when overexpressing α4 protein. 2017 Jan 4
8 27352821 Microcystin-LR induces a wide variety of biochemical changes in the A549 human non-small cell lung cancer cell line: Roles for protein phosphatase 2A and its substrates. 2017 Mar 3
9 26506538 Microcystin-LR promotes proliferation by activating Akt/S6K1 pathway and disordering apoptosis and cell cycle associated proteins phosphorylation in HL7702 cells. 2016 Jan 5 2
10 23929704 Alterations of tau and VASP during microcystin-LR-induced cytoskeletal reorganization in a human liver cell line. 2015 Jan 1
11 25922137 The role of PP2A-associated proteins and signal pathways in microcystin-LR toxicity. 2015 Jul 2 1
12 26341421 Different responses of primary normal human hepatocytes and human hepatoma cells toward cyanobacterial hepatotoxin microcystin-LR. 2015 Oct 1
13 23436320 Microcystin-LR induces protein phosphatase 2A alteration in a human liver cell line. 2014 Nov 5
14 22135143 Effect of microcystin-LR on protein phosphatase 2A and its function in human amniotic epithelial cells. 2011 Dec 1
15 19501114 The effect of structural variation in 21 microcystins on their inhibition of PP2A and the effect of replacing cys269 with glycine. 2009 Sep 15 2
16 19940183 Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins. 2009 Nov 25 1
17 18812183 Assessment of protein phosphatase in a re-usable rapid assay format in detecting microcystins and okadaic acid as a precursor to biosensor development. 2008 Dec 1 5
18 17055435 Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins. 2006 Oct 20 1
19 14741332 Microcystin-LR and okadaic acid-induced cellular effects: a dualistic response. 2004 Jan 16 1
20 15294913 Redox regulation of the calcium/calmodulin-dependent protein kinases. 2004 Oct 22 1
21 18429239 Use of protein phosphatase inhibitors. 2003 May 1
22 11377737 Characterization of a novel serine/threonine protein phosphatase (PfPPJ) from the malaria parasite, Plasmodium falciparum. 2001 Jun 1
23 10669024 An ultrasensitive competitive binding assay for the detection of toxins affecting protein phosphatases. 2000 Mar 1
24 10187782 Cyanobacterial PPP family protein phosphatases possess multifunctional capabilities and are resistant to microcystin-LR. 1999 Apr 9 1
25 10222000 A fluorescent microplate assay for microcystin-LR. 1999 May 1 2
26 8602355 Reversible protein phosphorylation modulates nucleotide excision repair of damaged DNA by human cell extracts. 1996 Feb 1 1
27 7702557 Inhibition of specific binding of okadaic acid to protein phosphatase 2A by microcystin-LR, calyculin-A and tautomycin: method of analysis of interactions of tight-binding ligands with target protein. 1995 Mar 15 1
28 8079372 In vitro neutralization of the inhibitory effect of Microcystin-LR to protein phosphatase 2A by antibody against the toxin. 1994 May 1
29 1331983 Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing. 1992 Oct 25 1
30 2171989 Sucrose-phosphate synthase is dephosphorylated by protein phosphatase 2A in spinach leaves. Evidence from the effects of okadaic acid and microcystin. 1990 Sep 17 1