| 1 |
34882257 | Is sleep bruxism related to the levels of enzymes involved in the serotonin synthesis pathway? | 2022 Apr |
2 |
| 2 |
35391733 | Herpes Simplex Virus-1 Induced Serotonin-Associated Metabolic Pathways Correlate With Severity of Virus- and Inflammation-Associated Ocular Disease. | 2022 |
1 |
| 3 |
35473609 | Tryptophan hydroxylase 1 drives glioma progression by modulating the serotonin/L1CAM/NF-κB signaling pathway. | 2022 Apr 26 |
3 |
| 4 |
33466782 | Serotonin in the Pathogenesis of Lymphocytic Colitis. | 2021 Jan 14 |
4 |
| 5 |
33517848 | Fluoxetine-induced hepatic lipid accumulation is linked to elevated serotonin production. | 2021 Sep |
1 |
| 6 |
34065903 | Serotonin Pathway of Tryptophan Metabolism in Small Intestinal Bacterial Overgrowth-A Pilot Study with Patients Diagnosed with Lactulose Hydrogen Breath Test and Treated with Rifaximin. | 2021 May 12 |
2 |
| 7 |
34285037 | Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation. | 2021 Sep |
2 |
| 8 |
34368536 | Comparison of Serotonin-Regulated Calcific Processes in Aortic and Mitral Valvular Interstitial Cells. | 2021 Aug 3 |
1 |
| 9 |
34771469 | TPH1 and 5-HT7 Receptor Overexpression Leading to Gemcitabine-Resistance Requires Non-Canonical Permissive Action of EZH2 in Pancreatic Ductal Adenocarcinoma. | 2021 Oct 22 |
1 |
| 10 |
34772352 | TPH1 gene polymorphism rs211105 is associated with serotonin and tryptophan hydroxylase 1 concentrations in acute pancreatitis patients. | 2021 Nov 12 |
1 |
| 11 |
32752885 | Discovery and biological characterization of a novel scaffold for potent inhibitors of peripheral serotonin synthesis. | 2020 Aug |
4 |
| 12 |
32801896 | Antiproliferative Effects of Telotristat Ethyl in Patients with Neuroendocrine Tumors: The TELEACE Real-World Chart Review Study. | 2020 |
2 |
| 13 |
32967429 | The serotonin reuptake transporter is reduced in the epithelium of active Crohn's disease and ulcerative colitis. | 2020 Dec 1 |
1 |
| 14 |
33215629 | Inhibition of mechanistic target of rapamycin signaling decreases levels of O-GlcNAc transferase and increases serotonin release in the human placenta. | 2020 Dec 11 |
1 |
| 15 |
30468670 | Role of platelet serotonin in innate immune cell recruitment. | 2019 Jan 1 |
1 |
| 16 |
31294376 | Characterization of Serotonin Signaling Components in Patients with Inflammatory Bowel Disease. | 2019 Aug |
1 |
| 17 |
29194046 | Updates on the biology of serotonin and tryptophan hydroxylase. | 2018 Feb |
1 |
| 18 |
29291611 | Gene Expression Profiling and Assessment of Vitamin D and Serotonin Pathway Variations in Patients With Irritable Bowel Syndrome. | 2018 Jan 30 |
1 |
| 19 |
29468941 | The serotonin hypothesis in pulmonary hypertension revisited: targets for novel therapies (2017 Grover Conference Series). | 2018 Apr-Jun |
3 |
| 20 |
29696773 | Complex phenotype of dyskeratosis congenita and mood dysregulation with novel homozygous RTEL1 and TPH1 variants. | 2018 Jun |
1 |
| 21 |
30351987 | Peripartum dietary supplementation of a small-molecule inhibitor of tryptophan hydroxylase 1 compromises infant, but not maternal, bone. | 2018 Dec 1 |
4 |
| 22 |
27866207 | Post-Stroke Fatigue May Be Associated with the Promoter Region of a Monoamine Oxidase A Gene Polymorphism. | 2017 |
1 |
| 23 |
28443016 | Genetics of Aggression in Alzheimer's Disease (AD). | 2017 |
1 |
| 24 |
28751217 | Human placenta expresses both peripheral and neuronal isoform of tryptophan hydroxylase. | 2017 Sep |
2 |
| 25 |
29035515 | Isoform-Specific Substrate Inhibition Mechanism of Human Tryptophan Hydroxylase. | 2017 Nov 21 |
1 |
| 26 |
26710093 | Tryptophan hydroxylase 1 gene polymorphisms alter prefrontal cortex activation during response inhibition. | 2016 Jan |
2 |
| 27 |
27144435 | Androgen suppresses testicular cancer cell growth in vitro and in vivo. | 2016 Jun 7 |
2 |
| 28 |
27497328 | TPH1 A218 allele is associated with suicidal behavior in Turkish population. | 2016 Jul |
1 |
| 29 |
25912293 | Preliminary Transcriptome Analysis in Lymphoblasts from Cluster Headache and Bipolar Disorder Patients Implicates Dysregulation of Circadian and Serotonergic Genes. | 2015 Jul |
1 |
| 30 |
26238767 | Decoy receptor 3 regulates the expression of tryptophan hydroxylase 1 in rheumatoid synovial fibroblasts. | 2015 Oct |
2 |
| 31 |
24903772 | Serotonin-related polymorphisms in TPH1 and HTR5A genes are not associated with escitalopram treatment response in Korean patients with major depression. | 2014 |
1 |
| 32 |
23665899 | Molecular dynamics simulation of tryptophan hydroxylase-1: binding modes and free energy analysis to phenylalanine derivative inhibitors. | 2013 May 10 |
2 |
| 33 |
24092348 | Serotonin transporter and serotonin receptors. | 2013 |
1 |
| 34 |
24265583 | Associations Between Variations in TPH1 , TPH2 and SLC6A4 Genes and Postpartum Depression: A Study in the Jordanian Population. | 2013 Jun |
1 |
| 35 |
22403677 | High fat diet alters lactation outcomes: possible involvement of inflammatory and serotonergic pathways. | 2012 |
2 |
| 36 |
22487062 | Mutations in LRP5 cause primary osteoporosis without features of OI by reducing Wnt signaling activity. | 2012 Apr 10 |
2 |
| 37 |
22754301 | Combined structure-based pharmacophore and 3D-QSAR studies on phenylalanine series compounds as TPH1 inhibitors. | 2012 |
2 |
| 38 |
22819790 | Increased expression of tryptophan-5-hydroxylase 1, but not 2, in brainstem as a result of intrauterine malnutrition. | 2012 Oct |
1 |
| 39 |
23008335 | Tryptophan hydroxylase-1 regulates immune tolerance and inflammation. | 2012 Oct 22 |
2 |
| 40 |
20818612 | Genetic models of serotonin (5-HT) depletion: what do they tell us about the developmental role of 5-HT? | 2011 Oct |
1 |
| 41 |
20945066 | TPH1 is associated with major depressive disorder but not with SSRI/SNRI response in Taiwanese patients. | 2011 Feb |
2 |
| 42 |
21073637 | Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome. | 2011 Mar |
1 |
| 43 |
21508359 | The effect of PTEN on serotonin synthesis and secretion from the carcinoid cell line BON. | 2011 Apr |
2 |
| 44 |
20043001 | Risk-taking behavior in a gambling task associated with variations in the tryptophan hydroxylase 2 gene: relevance to psychiatric disorders. | 2010 Apr |
1 |
| 45 |
20144688 | Common genetic variations in TPH1/TPH2 genes are not associated with schizophrenia in Japanese population. | 2010 Mar 26 |
2 |
| 46 |
20204739 | The serotonin hypothesis of pulmonary hypertension revisited. | 2010 |
2 |
| 47 |
20213726 | Common variants in the TPH1 and TPH2 regions are not associated with persistent ADHD in a combined sample of 1,636 adult cases and 1,923 controls from four European populations. | 2010 Jul |
2 |
| 48 |
20329492 | Tryptophan hydroxylase 1 expression is increased in phenotype-altered canine and human degenerative myxomatous mitral valves. | 2010 Jan |
4 |
| 49 |
20396435 | Association between Serotonin-Related Polymorphisms in 5HT2A, TPH1, TPH2 Genes and Bipolar Disorder in Korean Population. | 2010 Mar |
1 |
| 50 |
20556201 | Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis. | 2010 Apr 14 |
2 |