Metformin

cyclin D1 ; Homo sapiens







38 Article(s)
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1 35236827 Metformin suppresses the growth of colorectal cancer by targeting INHBA to inhibit TGF-β/PI3K/AKT signaling transduction. 2022 Mar 2 1
2 35264157 Novel sequential therapy with metformin enhances the effects of cisplatin in testicular germ cell tumours via YAP1 signalling. 2022 Mar 9 1
3 33350292 Metformin promotes apoptosis in primary breast cancer cells by downregulation of cyclin D1 and upregulation of P53 through an AMPK-alpha independent mechanism 2021 Apr 30 4
4 33652909 Metformin Increases Survival in Hypopharyngeal Cancer Patients with Diabetes Mellitus: Retrospective Cohort Study and Cell-Based Analysis. 2021 Feb 26 1
5 34235153 Additive Antiproliferative and Antiangiogenic Effects of Metformin and Pemetrexed in a Non-Small-Cell Lung Cancer Xenograft Model. 2021 1
6 31892560 Metformin Inhibits Proliferation and Tumor Growth of QGP-1 Pancreatic Neuroendocrine Tumor Cells by Inducing Cell Cycle Arrest and Apoptosis. 2020 Jan 1
7 31244286 Metformin Modulates Cyclin D1 and P53 Expression to Inhibit Cell Proliferation and to Induce Apoptosis in Cervical Cancer Cell Lines. 2019 Jun 1 2
8 31455378 Metformin targets a YAP1-TEAD4 complex via AMPKα to regulate CCNE1/2 in bladder cancer cells. 2019 Aug 27 2
9 31744691 Metformin inhibits cell proliferation in SKM-1 cells via AMPK-mediated cell cycle arrest. 2019 Dec 1
10 29472557 Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms. 2018 Feb 22 1
11 29693804 Synergistic Growth Inhibitory Effects of Chrysin and Metformin Combination on Breast Cancer Cells through hTERT and Cyclin D1 Suppression 2018 Apr 25 2
12 29920623 Synergistic Anti-proliferative Effects of Metformin and Silibinin Combination on T47D Breast Cancer Cells via hTERT and Cyclin D1 Inhibition. 2018 Dec 1
13 27128966 Metformin induces degradation of cyclin D1 via AMPK/GSK3β axis in ovarian cancer. 2017 Feb 6
14 27305912 Proteomic modulation in breast tumors after metformin exposure: results from a "window of opportunity" trial. 2017 Feb 2
15 28045889 Metformin Induces Growth Inhibition and Cell Cycle Arrest by Upregulating MicroRNA34a in Renal Cancer Cells. 2017 Jan 3 1
16 28440424 Therapeutic potential of the antidiabetic drug metformin in small bowel adenocarcinoma. 2017 Jun 1
17 29871302 [Metformin's effect on 5-fluorouracil,cisplatin,paclitaxel in laryngocarcinoma Hep-2 cells]. 2017 Apr 5 5
18 26986571 Anticancer effect of metformin on estrogen receptor-positive and tamoxifen-resistant breast cancer cell lines. 2016 May 1
19 27779693 Metformin potentiates the anticancer activities of gemcitabine and cisplatin against cholangiocarcinoma cells in vitro and in vivo. 2016 Dec 2
20 25305450 Metformin displays anti-myeloma activity and synergistic effect with dexamethasone in in vitro and in vivo xenograft models. 2015 Jan 28 1
21 25854169 Metformin inhibits thyroid cancer cell growth, migration, and EMT through the mTOR pathway. 2015 Aug 2
22 26196392 Metformin Induced AMPK Activation, G0/G1 Phase Cell Cycle Arrest and the Inhibition of Growth of Esophageal Squamous Cell Carcinomas In Vitro and In Vivo. 2015 2
23 26398221 Antitumor effect of metformin on cholangiocarcinoma: In vitro and in vivo studies. 2015 Dec 1
24 25419360 Metformin inhibits cell growth by upregulating microRNA-26a in renal cancer cells. 2014 1
25 21676631 Metformin inhibits renal cell carcinoma in vitro and in vivo xenograft. 2013 Feb 1
26 22773548 Metformin decreases hepatocellular carcinoma risk in a dose-dependent manner: population-based and in vitro studies. 2013 Apr 1
27 23229592 Antitumor effect of metformin in esophageal cancer: in vitro study. 2013 Feb 1
28 23803693 Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors. 2013 Dec 1
29 24008375 Metformin suppresses hepatocellular carcinoma cell growth through induction of cell cycle G1/G0 phase arrest and p21CIP and p27KIP expression and downregulation of cyclin D1 in vitro and in vivo. 2013 Nov 2
30 24351837 The antidiabetic drug metformin inhibits the proliferation of bladder cancer cells in vitro and in vivo. 2013 Dec 18 2
31 22389381 Metformin inhibits growth and decreases resistance to anoikis in medullary thyroid cancer cells. 2012 Jun 1
32 23151022 In vitro and in vivo anti-tumor effect of metformin as a novel therapeutic agent in human oral squamous cell carcinoma. 2012 Nov 14 2
33 21717584 Metformin induces G1 cell cycle arrest and inhibits cell proliferation in nasopharyngeal carcinoma cells. 2011 Aug 2
34 20813708 [Effects of metformin on proliferation of human colon carcinoma cell line SW-480]. 2010 Aug 3
35 19221498 Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro. 2009 Mar 15 1
36 19440038 Metformin induces unique biological and molecular responses in triple negative breast cancer cells. 2009 Jul 1 1
37 18212742 The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level. 2008 Jun 5 3
38 19046439 Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1. 2008 Dec 1 3