| 1 |
35397430 | Synthesis and characterization of a new Positron emission tomography probe for orexin 2 receptors neuroimaging. | 2022 Jun |
2 |
| 2 |
33676539 | Protecting P-glycoprotein at the blood-brain barrier from degradation in an Alzheimer's disease mouse model. | 2021 Mar 6 |
1 |
| 3 |
30679998 | Nrf2 overexpression protects against paraquat-induced A549 cell injury primarily by upregulating P-glycoprotein and reducing intracellular paraquat accumulation. | 2019 Feb |
1 |
| 4 |
31305009 | Resistance of t(17;19)-acute lymphoblastic leukemia cell lines to multiagents in induction therapy. | 2019 Sep |
1 |
| 5 |
28707509 | Intestinal absorption of pallidifloside D are limited by P-glycoprotein in mice. | 2018 Jul |
1 |
| 6 |
29986516 | Detection of the Mitochondrial Membrane Potential by the Cationic Dye JC-1 in L1210 Cells with Massive Overexpression of the Plasma Membrane ABCB1 Drug Transporter. | 2018 Jul 7 |
1 |
| 7 |
25264342 | Effects of the inhibition of intestinal P-glycoprotein on aliskiren pharmacokinetics in cynomolgus monkeys. | 2015 Jan |
1 |
| 8 |
26324318 | Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice. | 2015 Sep 1 |
3 |
| 9 |
24280122 | The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram. | 2014 Mar 15 |
2 |
| 10 |
24492412 | Downregulation of CYP3A and P-glycoprotein in the secondary inflammatory response of mice with dextran sulfate sodium-induced colitis and its contribution to cyclosporine A blood concentrations. | 2014 |
2 |
| 11 |
24980806 | Cyclosporin A affects the bioavailability of ginkgolic acids via inhibition of P-gp and BCRP. | 2014 Nov |
2 |
| 12 |
24011632 | Pharmacokinetic and pharmacodynamic study of Gefitinib in a mouse model of non-small-cell lung carcinoma with brain metastasis. | 2013 Nov |
1 |
| 13 |
22644589 | Discrepancies in the P-glycoprotein-mediated transport of (18)F-MPPF: a pharmacokinetic study in mice and non-human primates. | 2012 Sep |
1 |
| 14 |
22768295 | Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter. | 2012 |
1 |
| 15 |
20230790 | A novel in vivo regulatory role of P-glycoprotein in alloimmunity. | 2010 Apr 9 |
3 |
| 16 |
20447559 | In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter. | 2010 May |
1 |
| 17 |
20460505 | The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature. | 2010 Jun 1 |
4 |
| 18 |
18445990 | P-glycoprotein limits the brain penetration of olopatadine hydrochloride, H1-receptor antagonist. | 2008 |
1 |
| 19 |
17204702 | In vivo evaluation of P-glycoprotein modulation of 8 PET radioligands used clinically. | 2007 Jan |
2 |
| 20 |
16384676 | Contributions of intestinal P-glycoprotein and CYP3A to oral bioavailability of cyclosporin A in mice treated with or without dexamethasone. | 2006 Feb 17 |
1 |
| 21 |
16939683 | Site-dependent contributions of P-glycoprotein and CYP3A to cyclosporin A absorption, and effect of dexamethasone in small intestine of mice. | 2006 Oct 16 |
5 |
| 22 |
15802827 | Limited role of P-glycoprotein in the intestinal absorption of cyclosporin A. | 2005 Apr |
5 |
| 23 |
15110893 | Improved penetration of docetaxel into the brain by co-administration of inhibitors of P-glycoprotein. | 2004 May |
2 |
| 24 |
15176436 | Uptake and efflux of quinacrine, a candidate for the treatment of prion diseases, at the blood-brain barrier. | 2004 Apr |
1 |
| 25 |
15638123 | Functional fluo-3/AM assay on P-glycoprotein transport activity in L1210/VCR cells by confocal microscopy. | 2004 Sep |
3 |
| 26 |
23285492 | 11C-Labeled rhodamine-123 | 2004 |
1 |
| 27 |
12673668 | Potentiation of domperidone-induced catalepsy by a P-glycoprotein inhibitor, cyclosporin A. | 2003 Apr |
2 |
| 28 |
12855665 | Increased penetration of paclitaxel into the brain by inhibition of P-Glycoprotein. | 2003 Jul |
1 |
| 29 |
14534356 | Pumping of drugs by P-glycoprotein: a two-step process? | 2003 Dec |
3 |
| 30 |
11739114 | P-gp-induced modulation of regulatory volume increase occurs via PKC in mouse proximal tubule. | 2002 Jan |
1 |
| 31 |
11880334 | Hyperosmotic mannitol activates basolateral NHE in proximal tubule from P-glycoprotein null mice. | 2002 Apr |
1 |
| 32 |
12003193 | Partial circumvention of P-glycoprotein-mediated multidrug resistance by doxorubicin-14-O-hemiadipate. | 2002 Feb |
1 |
| 33 |
12069596 | Real-time monitoring of P-glycoprotein activation in living cells. | 2002 Jun 25 |
2 |
| 34 |
12107549 | Influence of chemosensitizers on resistance mechanisms in daunorubicin-resistant Ehrlich ascites tumour cells. | 2002 Jun |
2 |
| 35 |
12128165 | Altered drug disposition of the platelet activating factor antagonist apafant in mdr1a knockout mice. | 2002 Aug |
1 |
| 36 |
11212278 | In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576. | 2001 Jan 15 |
1 |
| 37 |
11368976 | Cyclosporin A inhibits the extrusion pump function of p-glycoprotein in the inner ear of mice treated with vinblastine and doxorubicin. | 2001 May 18 |
2 |
| 38 |
11489261 | Interactions of 1-methyl-4-phenylpyridinium and other compounds with P-glycoprotein: relevance to toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. | 2001 Aug 10 |
1 |
| 39 |
11718240 | Doxorubicin ototoxicity is induced in mice by combination treatment with cyclosporin A. | 2001 Oct |
5 |
| 40 |
10661503 | Disruption of mdr1a p-glycoprotein gene results in dysfunction of blood-inner ear barrier in mice. | 2000 Jan 3 |
2 |
| 41 |
11741243 | Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene. | 2000 |
1 |
| 42 |
10206323 | Contribution of P-glycoprotein to bunitrolol efflux across blood-brain barrier. | 1999 Mar |
1 |
| 43 |
10220486 | Disposition of ivermectin and cyclosporin A in CF-1 mice deficient in mdr1a P-glycoprotein. | 1999 May |
1 |
| 44 |
9723952 | Complete in vivo reversal of P-glycoprotein pump function in the blood-brain barrier visualized with positron emission tomography. | 1998 Aug |
2 |
| 45 |
9732409 | Saquinavir, an HIV protease inhibitor, is transported by P-glycoprotein. | 1998 Sep |
1 |
| 46 |
8620476 | Expression of P-glycoprotein, encoded by MDR 1 gene, a metabolically active efflux pump in murine mast cells. | 1996 Mar 29 |
1 |
| 47 |
8647944 | P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. | 1996 Jun 1 |
1 |
| 48 |
8949985 | The abamectin derivative ivermectin is a potent P-glycoprotein inhibitor. | 1996 Sep |
5 |
| 49 |
7628053 | Changes in doxorubicin distribution and toxicity in mice pretreated with the cyclosporin analogue SDZ PSC 833. | 1995 |
1 |
| 50 |
8845485 | Cardiotoxicity in the SCID mouse following administration of doxorubicin and cyclosporin A. | 1995 Dec |
1 |