Sirolimus

transformation related protein 53, pseudogene ; Mus musculus







18 Article(s)
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1 32738450 p53 haploinsufficiency and increased mTOR signalling define a subset of aggressive hepatocellular carcinoma. 2021 Jan 1
2 33469286 Delivery of Rapamycin by Liposomes Synergistically Enhances the Chemotherapy Effect of 5-Fluorouracil on Colorectal Cancer. 2021 1
3 33508145 mTORC1 promotes mineralization via p53 pathway. 2021 Feb 3
4 34853727 Tubule-specific deletion of LincRNA-p21ameliorates lipotoxic kidney injury. 2021 Dec 3 1
5 35187108 p53 SUMOylation Mediates AOPP-Induced Endothelial Senescence and Apoptosis Evasion. 2021 1
6 29257864 Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways. 2018 Apr 18 1
7 28713484 Moderate Autophagy Inhibits Vascular Smooth Muscle Cell Senescence to Stabilize Progressed Atherosclerotic Plaque via the mTORC1/ULK1/ATG13 Signal Pathway. 2017 1
8 25438952 Rapamycin protects against apoptotic neuronal death and improves neurologic function after traumatic brain injury in mice via modulation of the mTOR-p53-Bax axis. 2015 Mar 2
9 23233735 Dietary immunosuppressants do not enhance UV-induced skin carcinogenesis, and reveal discordance between p53-mutant early clones and carcinomas. 2013 Feb 1
10 23454868 Temporal mTOR inhibition protects Fbxw7-deficient mice from radiation-induced tumor development. 2013 Feb 4
11 22161643 Rapamycin impairs UV induction of mutant-p53 overexpressing cell clusters without affecting tumor onset. 2012 Sep 15 2
12 22559167 Novel synergistic antitumor effects of rapamycin with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model. 2012 May 4 5
13 23123616 Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/- mice. 2012 Oct 2
14 23128359 Rapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency. 2012 Oct 1
15 19435901 Rapamycin prevents early onset of tumorigenesis in an oral-specific K-ras and p53 two-hit carcinogenesis model. 2009 May 15 1
16 15897901 Regulation of the phosphorylation and integrity of protein synthesis initiation factor eIF4GI and the translational repressor 4E-BP1 by p53. 2005 Jul 14 2
17 11309295 p53/p21(CIP1) cooperate in enforcing rapamycin-induced G(1) arrest and determine the cellular response to rapamycin. 2001 Apr 15 2
18 10771484 FRAP DNA-dependent protein kinase mediates a late signal transduced from ultraviolet-induced DNA damage. 2000 May 2