Leukotrienes

phospholipase A2 group IVA ; Homo sapiens







23 Article(s)
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Pub. Year
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1 32331436 The Cytosolic Phospholipase A2α N-terminal C2 Domain Binds and Oligomerizes on Membranes with Positive Curvature. 2020 Apr 22 1
2 32707189 Functional role of phosphatidylcholine-specific phospholipase C in regulating leukotriene synthesis and degranulation in human eosinophils. 2020 Oct 5 5
3 33023184 cPLA2α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation. 2020 Oct 2 1
4 22192589 Pharmacophore-based discovery of a novel cytosolic phospholipase A(2)α inhibitor. 2012 Jan 15 1
5 22378731 Association of PLA2G4A with myocardial infarction is modulated by dietary PUFAs. 2012 Apr 1
6 21247147 Functional characterization of mutations in inherited human cPLA₂ deficiency. 2011 Mar 15 1
7 18451993 Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction. 2008 Jun 1
8 18636547 Regulation of Wnt/beta-catenin pathway by cPLA2alpha and PPARdelta. 2008 Oct 1 1
9 18665843 In vitro allergen challenge of peripheral blood induces differential gene expression in mononuclear cells of asthmatic patients: inhibition of cytosolic phospholipase A2alpha overcomes the asthma-associated response. 2008 Oct 1
10 18801329 Thermodynamic characterization of cytosolic phospholipase A2 alpha inhibitors. 2008 Dec 15 1
11 18829119 Blockade of cytosolic phospholipase A2 alpha prevents experimental autoimmune encephalomyelitis and diminishes development of Th1 and Th17 responses. 2008 Nov 15 2
12 16967052 Effects of pyrrophenone, an inhibitor of group IVA phospholipase A2, on eicosanoid and PAF biosynthesis in human neutrophils. 2006 Oct 1
13 15801331 Impact of a soluble phospholipase A2 inhibitor on inhaled allergen challenge in subjects with asthma. 2005 Feb 1
14 15507318 The role of TFIID, the initiator element and a novel 5' TFIID binding site in the transcriptional control of the TATA-less human cytosolic phospholipase A2-alpha promoter. 2004 Nov 5 2
15 12401196 Role of caspases in TNF-mediated regulation of cPLA(2). 2002 Oct 30 1
16 11404253 CTP:phosphocholine cytidylyltransferase inhibition by ceramide via PKC-alpha, p38 MAPK, cPLA2, and 5-lipoxygenase. 2001 Jul 2
17 10760518 Cytokine-mediated cPLA(2) phosphorylation is regulated by multiple MAPK family members. 2000 Apr 7 1
18 10934206 Tumor necrosis factor-alpha generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade. 2000 Oct 13 1
19 10970711 Increased levels of cytosolic phospholipase A2 in dyslexics. 2000 Jul-Aug 2
20 11080682 Localization and regulation of cytosolic phospholipase A(2). 2000 Oct 31 1
21 10319815 Crystal structure of human cytosolic phospholipase A2 reveals a novel topology and catalytic mechanism. 1999 Apr 30 1
22 9060638 Adenovirus E3-10.4K/14.5K protein complex inhibits tumor necrosis factor-induced translocation of cytosolic phospholipase A2 to membranes. 1997 Apr 1
23 7862535 Identification of a 27 bp 5'-flanking region element responsible for the low level constitutive expression of the human cytosolic phospholipase A2 gene. 1995 Jan 25 2