Dinoprostone

phospholipase A2 group IVA ; Homo sapiens







87 Article(s)
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1 35089606 ATF6α promotes prostate cancer progression by enhancing PLA2G4A-mediated arachidonic acid metabolism and protecting tumor cells against ferroptosis. 2022 Apr 1
2 34206390 A Metalloproteinase Induces an Inflammatory Response in Preadipocytes with the Activation of COX Signalling Pathways and Participation of Endogenous Phospholipases A2. 2021 Jun 22 1
3 34246631 Tyrosine phosphatase STEP is a key regulator of glutamate-induced prostaglandin E2 release from neurons. 2021 Aug 3
4 34729107 Anticancer Effects of Helminthostachys zeylanica Ethyl acetate Extracts on Human Gastric Cancer Cells through Downregulation of the TNF-α-activated COX-2-cPLA2-PGE2 Pathway. 2021 3
5 32620771 Cytosolic phospholipase A2-α participates in lipid body formation and PGE2 release in human neutrophils stimulated with an L-amino acid oxidase from Calloselasma rhodostoma venom. 2020 Jul 3 1
6 32879137 Epigenetic regulation of the PGE2 pathway modulates macrophage phenotype in normal and pathologic wound repair. 2020 Sep 3 6
7 33023184 cPLA2α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation. 2020 Oct 2 3
8 33247192 Weak acids induce PGE2 production in human oesophageal cells: novel mechanisms underlying GERD symptoms. 2020 Nov 27 3
9 33255269 A Representative GIIA Phospholipase A2 Activates Preadipocytes to Produce Inflammatory Mediators Implicated in Obesity Development. 2020 Nov 24 1
10 31492557 Annexin10 promotes extrahepatic cholangiocarcinoma metastasis by facilitating EMT via PLA2G4A/PGE2/STAT3 pathway. 2019 Sep 3
11 30122655 Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration. 2018 Sep 12 1
12 28007986 Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy. 2017 Feb 1
13 28188254 Differential Effects of Oxytocin Receptor Antagonists, Atosiban and Nolasiban, on Oxytocin Receptor-Mediated Signaling in Human Amnion and Myometrium. 2017 Apr 1
14 28651842 Sulodexide prevents activation of the PLA2/COX-2/VEGF inflammatory pathway in human retinal endothelial cells by blocking the effect of AGE/RAGE. 2017 Oct 15 1
15 28690034 Interplay of inflammatory gene expression in pericytes following Japanese encephalitis virus infection. 2017 Nov 1
16 27554058 Cytosolic phospholipase A2α increases proliferation and de-differentiation of human renal tubular epithelial cells. 2016 Nov 1
17 27932980 TNF-α-Induced cPLA2 Expression via NADPH Oxidase/Reactive Oxygen Species-Dependent NF-κB Cascade on Human Pulmonary Alveolar Epithelial Cells. 2016 1
18 28042832 R-Flurbiprofen Traps Prostaglandins within Cells by Inhibition of Multidrug Resistance-Associated Protein-4. 2016 Dec 30 1
19 25893499 Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes. 2015 4
20 26081696 Berberine induces apoptosis by suppressing the arachidonic acid metabolic pathway in hepatocellular carcinoma. 2015 Sep 1
21 26183771 Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation. 2015 Nov 2
22 26389963 cAMP-Inhibits Cytoplasmic Phospholipase A₂ and Protects Neurons against Amyloid-β-Induced Synapse Damage. 2015 Sep 16 3
23 24170779 Polarization of the innate immune response by prostaglandin E2: a puzzle of receptors and signals. 2014 Jan 1
24 24363440 Urocortin increased endothelial ICAM1 by cPLA2-dependent NF-κB and PKA pathways in HUVECs. 2014 Feb 3
25 24441870 TNF-α induces cytosolic phospholipase A2 expression via Jak2/PDGFR-dependent Elk-1/p300 activation in human lung epithelial cells. 2014 Mar 15 1
26 23766266 Cathelicidin LL-37 induces angiogenesis via PGE2-EP3 signaling in endothelial cells, in vivo inhibition by aspirin. 2013 Aug 1
27 24101387 The effect of reactive oxygen species on the synthesis of prostanoids from arachidonic acid. 2013 Aug 4
28 24349530 Cytosolic phospholipase A2 regulates TNF-induced production of joint destructive effectors in synoviocytes. 2013 5
29 22227093 Signaling pathways involved in the regulation of TNFα-induced toll-like receptor 2 expression in human gingival fibroblasts. 2012 Mar 1
30 22673578 Group IVA phospholipase A₂ optimizes ovulation and fertilization in rodents through induction of and metabolic coupling with prostaglandin endoperoxide synthase 2. 2012 Sep 1
31 22696602 Flow-induced prostaglandin E2 release regulates Na and K transport in the collecting duct. 2012 Sep 1
32 22831644 The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cells. 2012 Dec 1
33 20850495 Involvement of the epidermal growth factor receptor in Pb²+-induced activation of cPLA₂/COX-2 genes and PGE₂ production in vascular smooth muscle cells. 2011 Jan 11 1
34 21702012 Cytosolic phospholipase A2 induction and prostaglandin E2 release by interleukin-1β via the myeloid differentiation factor 88-dependent pathway and cooperation of p300, Akt, and NF-κB activity in human rheumatoid arthritis synovial fibroblasts. 2011 Oct 1
35 19948080 Ellagic acid inhibits lipopolysaccharide-induced expression of enzymes involved in the synthesis of prostaglandin E2 in human monocytes. 2010 Apr 1
36 20227521 Decrease in expression or activity of cytosolic phospholipase A2alpha increases cyclooxygenase-1 action: A cross-talk between key enzymes in arachidonic acid pathway in prostate cancer cells. 2010 Jul 1
37 20307736 Effect of cytosolic phospholipase A2 on proinflammatory cytokine-induced bone resorptive genes including receptor activator of nuclear factor kappa B ligand in human dental pulp cells. 2010 Apr 1
38 20379791 Alcohol-induced interactive phosphorylation of Src and toll-like receptor regulates the secretion of inflammatory mediators by human astrocytes. 2010 Dec 1
39 20410594 Preventive effects of a kampo medicine, orento on inflammatory responses in lipopolysaccharide treated human gingival fibroblasts. 2010 1
40 19847291 Eicosanoid release is increased by membrane destabilization and CFTR inhibition in Calu-3 cells. 2009 Oct 22 1
41 18029351 Activation of cytosolic phospholipase A2alpha through nitric oxide-induced S-nitrosylation. Involvement of inducible nitric-oxide synthase and cyclooxygenase-2. 2008 Feb 8 1
42 19087588 [Effect of lipopolysaccharide of Porphyromonas gingivalis on prostaglandin E2 biosynthetic pathway in human monocytic cell strain THP-1]. 2008 Aug 1
43 17643350 Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophils. 2007 Sep 3
44 16299051 Regulatory features of interleukin-1beta-mediated prostaglandin E2 synthesis in airway smooth muscle. 2006 Mar 1
45 16458424 Cytoplasmic phospholipase A2 expression in human colon adenocarcinoma is correlated with cyclooxygenase-2 expression and contributes to prostaglandin E2 production. 2006 Nov 18 2
46 16467083 Homeodomain-interacting protein kinase-2 restrains cytosolic phospholipase A2-dependent prostaglandin E2 generation in human colorectal cancer cells. 2006 Feb 1 7
47 16675300 Gene expression of arachidonate cyclooxygenase pathway leading to the delayed synthesis of prostaglandins E2 and F2alpha in response to phorbol 12-myristate 13-acetate and action of these prostanoids during life cycle of adipocytes. 2006 Apr 1
48 16709925 Induction of Fc gammaRIIA expression in myeloid PLB cells during differentiation depends on cytosolic phospholipase A2 activity and is regulated via activation of CREB by PGE2. 2006 Sep 1 1
49 16741257 Polyamine-mediated reduction in human airway epithelial migration in response to wounding is PGE2 dependent through decreases in COX-2 and cPLA2 protein levels. 2006 Oct 1
50 16859643 Differential production of leukotriene B4 or prostaglandin E2 by WKYMVm or serum amyloid A via formyl peptide receptor-like 1. 2006 Sep 28 2