pyrazolanthrone

mitogen-activated protein kinase 14 ; Homo sapiens







67 Article(s)
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1 34199278 Combined Effect of Deoxynivalenol (DON) and Porcine Circovirus Type 2 (Pcv2) on Inflammatory Cytokine mRNA Expression. 2021 Jun 13 1
2 34411914 Tingenone and 22-hydroxytingenone target oxidative stress through downregulation of thioredoxin, leading to DNA double-strand break and JNK/p38-mediated apoptosis in acute myeloid leukemia HL-60 cells. 2021 Oct 1
3 32174780 Suppressive effects of S100A8 and S100A9 on neutrophil apoptosis by cytokine release of human bronchial epithelial cells in asthma. 2020 1
4 30368882 MAPKs and NF-κB-mediated acrylamide-induced neuropathy in rat striatum and human neuroblastoma cells SY5Y. 2019 Mar 1
5 31505769 Echinochrome A Promotes Ex Vivo Expansion of Peripheral Blood-Derived CD34+ Cells, Potentially through Downregulation of ROS Production and Activation of the Src-Lyn-p110δ Pathway. 2019 Sep 9 1
6 29264665 Apigenin reduces the Toll-like receptor-4-dependent activation of NF-κB by suppressing the Akt, mTOR, JNK, and p38-MAPK. 2018 Mar 1
7 29749481 Baicalein induces the apoptosis of HCT116 human colon cancer cells via the upregulation of DEPP/Gadd45a and activation of MAPKs. 2018 Aug 1
8 30003858 The Drug Combination of SB202190 and SP600125 Significantly Inhibit the Growth and Metastasis of Olaparib-resistant Ovarian Cancer Cell. 2018 1
9 30073566 Hyperbaric Oxygen Alleviates the Inflammatory Response Induced by LPS Through Inhibition of NF-κB/MAPKs-CCL2/CXCL1 Signaling Pathway in Cultured Astrocytes. 2018 Dec 1
10 30439377 Induction of functional erythropoietin and erythropoietin receptor gene expression by gamma-aminobutyric acid and piperine in kidney epithelial cells. 2018 Dec 15 1
11 28389245 Thymol inhibits bladder cancer cell proliferation via inducing cell cycle arrest and apoptosis. 2017 Sep 16 1
12 28432555 Rotundarpene inhibits TNF-α-induced activation of the Akt, mTOR, and NF-κB pathways, and the JNK and p38 associated with production of reactive oxygen species. 2017 Oct 1
13 28455228 Brusatol inhibits growth and induces apoptosis in pancreatic cancer cells via JNK/p38 MAPK/NF-κb/Stat3/Bcl-2 signaling pathway. 2017 Jun 10 1
14 28962172 Psoralen stimulates osteoblast proliferation through the activation of nuclear factor-κB-mitogen-activated protein kinase signaling. 2017 Sep 1
15 26497035 Thrombin/Matrix Metalloproteinase-9-Dependent SK-N-SH Cell Migration is Mediated Through a PLC/PKC/MAPKs/NF-κB Cascade. 2016 Nov 1
16 27096061 Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes. 2016 Jan 1
17 27106512 Amentoflavone enhances osteogenesis of human mesenchymal stem cells through JNK and p38 MAPK pathways. 2016 Jul 1
18 27490539 Upregulation of Human ST8Sia VI (α2,8-Sialyltransferase) Gene Expression by Physcion in SK-N-BE(2)-C Human Neuroblastoma Cells. 2016 Aug 2 1
19 27570977 Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways. 2016 2
20 27597132 Genistein induces apoptosis by down-regulating thioredoxin-1 in human hepatocellular carcinoma SNU-449 cells. 2016 Nov 1
21 25446857 Carnosic acid protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro model of Parkinson's disease: involvement of antioxidative enzymes induction. 2015 Jan 5 1
22 25573072 Combination treatment with triptolide and hydroxycamptothecin synergistically enhances apoptosis in A549 lung adenocarcinoma cells through PP2A-regulated ERK, p38 MAPKs and Akt signaling pathways. 2015 Mar 1
23 25611974 Thymoquinone induces caspase-independent, autophagic cell death in CPT-11-resistant lovo colon cancer via mitochondrial dysfunction and activation of JNK and p38. 2015 Feb 11 1
24 25619392 Resveratrol induces apoptosis of human chronic myelogenous leukemia cells in vitro through p38 and JNK-regulated H2AX phosphorylation. 2015 Mar 1
25 25862966 Selective modulation of MAPKs contribute to the anti-proliferative and anti-inflammatory activities of 1,7-dihydroxy-3,4-dimethoxyxanthone in rheumatoid arthritis-derived fibroblast-like synoviocyte MH7A cells. 2015 Jun 20 1
26 26238193 NOV inhibits proliferation while promoting apoptosis and migration in osteosarcoma cell lines through p38/MAPK and JNK/MAPK pathways. 2015 Oct 1
27 26645893 Melatonin Induces Cell Apoptosis in AGS Cells Through the Activation of JNK and P38 MAPK and the Suppression of Nuclear Factor-Kappa B: a Novel Therapeutic Implication for Gastric Cancer. 2015 3
28 26783410 Bufalin Induces Mitochondria-Dependent Apoptosis in Pancreatic and Oral Cancer Cells by Downregulating hTERT Expression via Activation of the JNK/p38 Pathway. 2015 2
29 23172806 Apoptosis induced by para-phenylenediamine involves formation of ROS and activation of p38 and JNK in chang liver cells. 2014 Sep 1
30 24706573 Triggering of p38 MAPK and JNK signaling is important for oleanolic acid-induced apoptosis via the mitochondrial death pathway in hypertrophic scar fibroblasts. 2014 Oct 1
31 24731555 Role of a Janus kinase 2-dependent signaling pathway in platelet activation. 2014 Jun 1
32 24963048 Functional p38 MAPK identified by biomarker profiling of pancreatic cancer restrains growth through JNK inhibition and correlates with improved survival. 2014 Dec 1 2
33 23067223 Anisomycin induces apoptosis of glucocorticoid resistant acute lymphoblastic leukemia CEM-C1 cells via activation of mitogen-activated protein kinases p38 and JNK. 2013 1
34 23211822 Age-related differences in signaling efficiency of human lens cells underpin differential wound healing response rates following cataract surgery. 2013 Jan 14 1
35 23376055 Roles of p38 MAPK and JNK in TGF-β1-induced human alveolar epithelial to mesenchymal transition. 2013 Feb 1
36 23796709 Piperlongumine selectively kills glioblastoma multiforme cells via reactive oxygen species accumulation dependent JNK and p38 activation. 2013 Jul 19 1
37 21946058 Arsenic trioxide inhibits Ewing's sarcoma cell invasiveness by targeting p38(MAPK) and c-Jun N-terminal kinase. 2012 Jan 1
38 22142847 p38 mitogen-activated protein kinase is a key regulator of 5-phenylselenyl- and 5-methylselenyl-methyl-2'-deoxyuridine-induced apoptosis in human HL-60 cells. 2012 Jan 6 1
39 23047827 Triglyceride accumulation in macrophages upregulates paraoxonase 2 (PON2) expression via ROS-mediated JNK/c-Jun signaling pathway activation. 2012 Nov-Dec 1
40 19852986 Corticotropin-releasing hormone attenuates vascular endothelial growth factor release from human HaCaT keratinocytes. 2010 Feb 25 1
41 20096139 ABL-N-induced apoptosis in human breast cancer cells is partially mediated by c-Jun NH2-terminal kinase activation. 2010 2
42 20177146 A pertussis toxin sensitive G-protein-independent pathway is involved in serum amyloid A-induced formyl peptide receptor 2-mediated CCL2 production. 2010 Apr 30 1
43 20380623 Deferoxamine mesylate is toxic for retinal pigment epithelium cells in vitro, and its toxicity is mediated by p38. 2010 Jun 1
44 20607722 Down-regulation of MMP-2 through the p38 MAPK-NF-kappaB-dependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion. 2010 Sep 1
45 19154444 Tachykinin receptor modulation of cyclooxygenase-2 expression in human polymorphonuclear leucocytes. 2009 Feb 1
46 19201463 Tumour necrosis factor alpha stimulates the production of monocyte chemoattractants by extravillous trophoblast cells via differential activation of MAPK pathways. 2009 Apr 1
47 19288033 Trans-Zeatin inhibits UVB-induced matrix metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts. 2009 Apr 1
48 19471112 Cisplatin reduces endothelial cell migration via regulation of type 2-matrix metalloproteinase activity. 2009 1
49 19505051 [The role of redox-dependent signal systems in the regulation of apoptosis under oxidative stress condition]. 2009 1
50 19558546 Bovine glycomacropeptide induces cytokine production in human monocytes through the stimulation of the MAPK and the NF-kappaB signal transduction pathways. 2009 Aug 2